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Biology and Biochemistry

D-Index
59
Citations
12096
World Ranking
12569
National Ranking
231

Overview

Genevieve Laureys is affiliated with Ghent University Hospital in Belgium and has contributed extensively to research in medicine, with a particular focus on biochemistry, genetics, and molecular biology. Their publications cover a wide range of topics, primarily within neurology, cancer research, molecular biology, oncology, and pediatrics, perinatology, and child health.

Their research emphasizes the study and treatment of neuroblastoma, cancer genomics and diagnostics, and cancer therapeutics and mechanisms. Additional areas of work include lung cancer research, cancer-related hypoxia and metabolism, renal cancers, and the quality of life for childhood cancer survivors.

Frequent co-authors collaborating with Genevieve Laureys include:

  • Ruth Ladenstein
  • Victoria Castel
  • Cormac Owens
  • Gudrun Schleiermacher
  • Bram De Wilde

Genevieve Laureys has published in several scientific venues, with multiple contributions to:

  • Journal of Clinical Oncology
  • European Journal of Pediatrics
  • Cancers
  • Journal of Hepatology
  • Epigenetics

Key recent papers authored or co-authored by Genevieve Laureys include:

  • Investigation of the Role of Dinutuximab Beta-Based Immunotherapy in the SIOPEN High-Risk Neuroblastoma 1 Trial (HR-NBL1), 2020, Cancers
  • Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications, 2020, Journal of Hepatology
  • Influence of Surgical Excision on the Survival of Patients With Stage 4 High-Risk Neuroblastoma: A Report From the HR-NBL1/SIOPEN Study, 2020, Journal of Clinical Oncology
  • Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1), 2021, Journal of Clinical Oncology
  • The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review, 2020, European Journal of Pediatrics

Best Publications

  • Identification of ALK as a major familial neuroblastoma predisposition gene

    Yaël P. Mossé;Marci Laudenslager;Luca Longo;Kristina A. Cole

  • Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

    N Bown;S Cotterill;M Lastowska;S O'Neill

  • Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma.

    H.N. Caron;P. van Sluis;J. de Kraker;J.P.M. Bökkerink

  • Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial

    Ruth Ladenstein;Ruth Ladenstein;Ulrike Pötschger;Andrew D J Pearson;Penelope Brock

  • Interleukin 2 with anti-GD2 antibody ch14.18/CHO (dinutuximab beta) in patients with high-risk neuroblastoma (HR-NBL1/SIOPEN): a multicentre, randomised, phase 3 trial

    Ruth Ladenstein;Ulrike Pötschger;Dominique Valteau-Couanet;Roberto Luksch

  • Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

    Sara De Brouwer;Katleen De Preter;Candy Kumps;Piotr Zabrocki

  • Identification of Biologically Active Chemokine Isoforms from Ascitic Fluid and Elevated Levels of CCL18/Pulmonary and Activation-regulated Chemokine in Ovarian Carcinoma

    Evemie Schutyser;Sofie Struyf;Paul Proost;Ghislain Opdenakker

  • ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma.

    Pascale De Paepe;Mathijs Baens;Mathijs Baens;Han van Krieken;Han van Krieken;Bruno Verhasselt;Bruno Verhasselt

  • I;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines

    N Van Roy;G Laureys;N C Cheng;P Willem

  • Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

    Joëlle Vermeulen;Katleen De Preter;Arlene Naranjo;Liesbeth Vercruysse

  • Unequivocal Delineation of Clinicogenetic Subgroups and Development of a New Model for Improved Outcome Prediction in Neuroblastoma

    Jo Vandesompele;Michael Baudis;Katleen De Preter;Nadine Van Roy

  • Quantification of MYCN, DDX1, and NAG Gene Copy Number in Neuroblastoma Using a Real-Time Quantitative PCR Assay

    Katleen De Preter;Frank Speleman;Valérie Combaret;John Lunec

  • Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization

    Jo Vandesompele;Nadine Van Roy;Mireille Van Gele;Geneviève Laureys

  • An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours

    P. Mestdagh;Erik Fredlund;Erik Fredlund;F. Pattyn;A. Rihani

  • Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification

    D. Plantaz;J. Vandesompele;N. Van Roy;M. Łastowska

  • Evidence for two tumour suppressor loci on chromosomal bands 1p35–36 involved in neuroblastoma: one probably imprinted, another associated with N-myc amplification

    Huib Caron;Martine Peter;Peter van Sluis;Frank Speleman

  • Randomized Trial of Prophylactic Granulocyte Colony-Stimulating Factor During Rapid COJEC Induction in Pediatric Patients With High-Risk Neuroblastoma: The European HR-NBL1/SIOPEN Study

    Ruth Ladenstein;Domonique Valteau-Couanet;Penelope Brock;Isaac Yaniv

  • The expression and role of CXC chemokines in colorectal cancer.

    Hannelien Verbeke;Sofie Struyf;Geneviève Laureys;Jozef Van Damme

  • MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors

    P Mestdagh;E Fredlund;F Pattyn;J H Schulte

  • Treatment of localised resectable neuroblastoma. Results of the LNESG1 study by the SIOP Europe Neuroblastoma Group.

    B De Bernardi;V Mosseri;H Rubie;V Castel

Frequent Co-Authors

Franki Speleman
Franki Speleman Ghent University
Jo Vandesompele
Jo Vandesompele Ghent University
Katleen De Preter
Katleen De Preter Ghent University
Nadine Van Roy
Nadine Van Roy Ghent University
Rogier Versteeg
Rogier Versteeg University of Amsterdam
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin
Anne De Paepe
Anne De Paepe Ghent University Hospital
Peter F. Ambros
Peter F. Ambros St Anna Children's Hospital
Ghislain Opdenakker
Ghislain Opdenakker Rega Institute for Medical Research
Andrew D.J. Pearson
Andrew D.J. Pearson Royal Marsden NHS Foundation Trust

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