Gen-Sheng Feng

Overview

Best Publications

• Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism.

  Milton W. Taylor;Gensheng Feng

  1561
  Citations

• SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

  Gen-Sheng Feng;Chi-Chung Hui;Tony Pawson

  835
  Citations

• Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

  Xuanyi Ma;Xin Qu;Wei Zhu;Yi-Shuan Li

  797
  Citations

• Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4

  Luc E. M. Marengère;Paul Waterhouse;Gordon S. Duncan;Hans-Willi Mittrücker

  676
  Citations

• Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp‐2

  Tracy M. Saxton;Mark J Henkemeyer;Mark J Henkemeyer;Stéphan Gasca;Stéphan Gasca;Randy Shen

  570
  Citations

• Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion

  De Hua Yu;Cheng-Kui Qu;Octavian Henegariu;Xiaolan Lu

  516
  Citations

• The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp.

  M. R. Kuhne;T. Pawson;G. E. Lienhard;Gen-Sheng Feng

  489
  Citations

• Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway.

  Min You;De-Hua Yu;Gen-Sheng Feng

  482
  Citations

• PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase

  Rebecca J. Chan;Gen Sheng Feng;Gen Sheng Feng

  380
  Citations

• Shp-2 Tyrosine Phosphatase: Signaling One Cell or Many

  Gen-Sheng Feng

  373
  Citations

• Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.

  Emilie A. Bard-Chapeau;Emilie A. Bard-Chapeau;Shuangwei Li;Jin Ding;Sharon S. Zhang

  363
  Citations

• Molecular Mechanism for the Shp-2 Tyrosine Phosphatase Function in Promoting Growth Factor Stimulation of Erk Activity

  Zhong-Qing Shi;De-Hua Yu;Morag Park;Mark Marshall

  296
  Citations

• Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice.

  M. Kozlowski;I. Mlinaric-Rascan;Gen-Sheng Feng;R. Shen

  286
  Citations

• SHP-2 Phosphatase Negatively Regulates the TRIF Adaptor Protein-Dependent Type I Interferon and Proinflammatory Cytokine Production

  Huazhang An;Wei Zhao;Jin Hou;Yan Zhang

  282
  Citations

• Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism

  Eric E. Zhang;Emilie Chapeau;Kazuki Hagihara;Gen-Sheng Feng

  279
  Citations

• The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp

  A. Kazlauskas;Gen-Sheng Feng;T. Pawson;M. Valius

  277
  Citations

• Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice.

  Liang Li;Lei Chen;Liang Hu;Yuan Liu

  269
  Citations

• Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction

  Gen-Sheng Feng;Tony Pawson

  258
  Citations

• Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2.

  Götz von Wichert;Beatrice Haimovich;Gen‐Sheng Feng;Michael P. Sheetz

  257
  Citations

• Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma

  Longyi Zheng;Wen Yang;Fuquan Wu;Chao Wang

  256
  Citations