D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 74 Citations 19,028 215 World Ranking 3507 National Ranking 1802

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

His primary areas of study are Protein tyrosine phosphatase, Signal transduction, SH2 domain, Cell biology and Phosphorylation. He interconnects Phosphatase, Molecular biology and Proto-oncogene tyrosine-protein kinase Src in the investigation of issues within Protein tyrosine phosphatase. The study incorporates disciplines such as Mutant, Cellular differentiation and STAT1 in addition to Molecular biology.

His Signal transduction research is multidisciplinary, relying on both Carcinogenesis and Cancer research. The various areas that Gen-Sheng Feng examines in his Cancer research study include TLR4, STAT3, Leukemia, PTEN and PTPN11. His Cell biology research is multidisciplinary, incorporating elements of Epidermal growth factor and Biomedical engineering.

His most cited work include:

  • Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism. (910 citations)
  • SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases (568 citations)
  • Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4 (466 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Protein tyrosine phosphatase, Cancer research, Signal transduction and Molecular biology are his primary areas of study. His study in Cell biology is interdisciplinary in nature, drawing from both Cellular differentiation and Fibroblast growth factor. His Protein tyrosine phosphatase research integrates issues from Phosphatase and Proto-oncogene tyrosine-protein kinase Src.

Gen-Sheng Feng has included themes like Protein kinase B, Carcinogenesis, Leukemia, PTEN and PTPN11 in his Cancer research study. His Molecular biology research incorporates elements of Mitogen-activated protein kinase and Mutant. Gen-Sheng Feng interconnects Tyrosine and Kinase in the investigation of issues within Phosphorylation.

He most often published in these fields:

  • Cell biology (44.10%)
  • Protein tyrosine phosphatase (45.41%)
  • Cancer research (28.82%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (28.82%)
  • Cell biology (44.10%)
  • Internal medicine (19.21%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Cell biology, Internal medicine, Immunology and Liver cancer. His Cancer research study integrates concerns from other disciplines, such as Tumor progression, Protein kinase B, Wnt signaling pathway and PTEN. His Protein tyrosine phosphatase and Proto-oncogene tyrosine-protein kinase Src study are his primary interests in Cell biology.

His Protein tyrosine phosphatase study improves the overall literature in Tyrosine. His Internal medicine research focuses on Endocrinology and how it relates to Estrogen receptor and Inflammation. His Immunology research integrates issues from Carcinogenesis, Knockout mouse, PTPN11 and Steatohepatitis.

Between 2015 and 2021, his most popular works were:

  • Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting (342 citations)
  • PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression. (66 citations)
  • Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis (45 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Gen-Sheng Feng mainly focuses on Cell biology, Cancer research, Immunology, Inflammation and Homeostasis. His work on Stem cell as part of general Cell biology study is frequently linked to Bile Salt Export Pump, therefore connecting diverse disciplines of science. Gen-Sheng Feng has researched Cancer research in several fields, including Proteasome and Glucocorticoid.

In general Immunology, his work in FOXP3, Granzyme B and CD8 is often linked to Granzyme linking many areas of study. His Inflammation study combines topics from a wide range of disciplines, such as Tumor necrosis factor alpha, Enhancer, Gene expression, Arthritis and Glucocorticoid receptor. The concepts of his Homeostasis study are interwoven with issues in Systemic autoimmunity, Autoimmunity, Knockout mouse and Competitive fitness.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism.

Milton W. Taylor;Gensheng Feng.
The FASEB Journal (1991)

1440 Citations

SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases

Gen-Sheng Feng;Chi-Chung Hui;T. Pawson.
Science (1993)

783 Citations

Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4

Luc E. M. Marengère;Paul Waterhouse;Gordon S. Duncan;Hans-Willi Mittrücker.
Science (1996)

611 Citations

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp‐2

Tracy M. Saxton;Tracy M. Saxton;Mark J Henkemeyer;Mark J Henkemeyer;Stéphan Gasca;Stéphan Gasca;Randy Shen.
The EMBO Journal (1997)

531 Citations

Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion

De Hua Yu;Cheng-Kui Qu;Octavian Henegariu;Xiaolan Lu.
Journal of Biological Chemistry (1998)

489 Citations

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp.

M. R. Kuhne;T. Pawson;G. E. Lienhard;Gen-Sheng Feng.
Journal of Biological Chemistry (1993)

489 Citations

Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

Xuanyi Ma;Xin Qu;Wei Zhu;Yi-Shuan Li.
Proceedings of the National Academy of Sciences of the United States of America (2016)

445 Citations

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway.

Min You;De-Hua Yu;Gen-Sheng Feng.
Molecular and Cellular Biology (1999)

435 Citations

Shp-2 Tyrosine Phosphatase: Signaling One Cell or Many

Gen-Sheng Feng.
Experimental Cell Research (1999)

354 Citations

Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.

Emilie A. Bard-Chapeau;Emilie A. Bard-Chapeau;Shuangwei Li;Jin Ding;Sharon S. Zhang.
Cancer Cell (2011)

319 Citations

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