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Neuroscience

D-Index
37
Citations
5406
World Ranking
8811
National Ranking
3729

Overview

Rueben A. Gonzales is affiliated with The University of Texas at Austin in the United States. Their primary field of research is Neuroscience, with a focus on Cellular and Molecular Neuroscience as well as related subfields such as Biomedical Engineering, Cognitive Neuroscience, Molecular Biology, and Pathology and Forensic Medicine.

The scientist's recent papers cover a range of topics primarily centered on neuropharmacology and neurobiological mechanisms related to alcohol use and neurotransmitter functions. Notable publications include:

  • "The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder" (2022, Biological Psychiatry)
  • "Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review" (2020, Pharmacology & Therapeutics)
  • "SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopaminergic neurotransmission under physiological conditions" (2023, Metallomics)
  • "Ethanol produces multiple electrophysiological effects on ventral tegmental area neurons in freely moving rats" (2020, Addiction Biology)
  • "Parametric study of a microdialysis probe and study of depletion effect using ethanol as a test analyte" (2022, Biochemical and Biophysical Research Communications)

Frequent coauthors in Gonzales's work include Tse-Ang Lee, Tanya Hutter, Roberto U. Cofresí, Donita L. Robinson, and Shannon L. Zandy. This collaboration network indicates interdisciplinary research contributions combining expertise in neuroscience, chemistry, and pharmacology.

Scientific dissemination often occurs in venues such as UNC Libraries, Alcohol, Biological Psychiatry, Pharmacology & Therapeutics, and Metallomics. Gonzales has published multiple times in UNC Libraries and Alcohol, suggesting a sustained engagement with neuropharmacology and addiction-related topics within these outlets.

Main research topics covered by Gonzales include:

  • Neuroscience and Neuropharmacology Research
  • Neurotransmitter Receptor Influence on Behavior
  • Memory and Neural Mechanisms
  • Microfluidic and Capillary Electrophoresis Applications
  • Alcohol Consumption and Health Effects
  • Alcoholism and Thiamine Deficiency
  • Stress Responses and Cortisol

Their work spans cellular and molecular investigations into the neural mechanisms underlying behavior and substance use disorders, with a specific emphasis on how neurotransmitter systems and molecular transporters affect neurobiological functions. Applications of microfluidic technologies and electrophoresis also feature prominently, reflecting a methodological diversity in addressing complex biological questions.

Best Publications

  • Suppression of Ethanol-Reinforced Behavior by Naltrexone Is Associated with Attenuation of the Ethanol-Induced Increase in Dialysate Dopamine Levels in the Nucleus Accumbens

    Rueben A. Gonzales;Friedbert Weiss

  • The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement.

    Rueben A. Gonzales;Martin O. Job;William M. Doyon

  • Characterization of the cholinergic stimulation of phosphoinositide hydrolysis in rat brain slices

    R. A. Gonzales;F. T. Crews

  • Ethanol Inhibition of N-Methyl-D-Aspartate-Stimulated Endogenous Dopamine Release from Rat Striatal Slices: Reversal by Glycine

    John J. Woodward;Rueben A. Gonzales

  • Ethanol-induced increases in dopamine extracellular concentration in rat nucleus accumbens are accounted for by increased release and not uptake inhibition.

    Hyeon Joo Yim;Rueben A Gonzales

  • Dopamine activity in the nucleus accumbens during consummatory phases of oral ethanol self-administration.

    William M. Doyon;Jennifer L. York;Laurea M. Diaz;Herman H. Samson

  • DARPP-32 and regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens.

    R. E. Maldve;T. A. Zhang;K. Ferrani-Kile;S. S. Schreiber

  • N-methyl-D-aspartate mediated responses decrease with age in Fischer 344 rat brain

    Rueben A. Gonzales;Laurie M. Brown;Thomas W. Jones;Robert D. Trent

  • Comparison of local and systemic ethanol effects on extracellular dopamine concentration in rat nucleus accumbens by microdialysis.

    Hyeon Joo Yim;Timothy J Schallert;Patrick K. Randall;Rueben A Gonzales

  • Ethanol inhibits N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat cortical slices.

    R A Gonzales;J J Woodward

  • Repeated Ethanol Intoxication Induces Behavioral Sensitization in the Absence of a Sensitized Accumbens Dopamine Response in C57BL/6J and DBA/2J Mice

    Agustin Zapata;Rueben A Gonzales;Toni S Shippenberg

  • Cholinergic- and adrenergic-stimulated inositide hydrolysis in brain: interaction, regional distribution, and coupling mechanisms.

    Rueben A Gonzales;Fulton T. Crews

  • Disparity between tonic and phasic ethanol-induced dopamine increases in the nucleus accumbens of rats

    Donita L. Robinson;Donita L. Robinson;Elaina C. Howard;Scott McConnell;Rueben A. Gonzales

  • Effect of operant self-administration of 10% ethanol plus 10% sucrose on dopamine and ethanol concentrations in the nucleus accumbens.

    William M. Doyon;Sheneil K. Anders;Vorani S. Ramachandra;Cristine L. Czachowski

  • Dissociation Between the Time Course of Ethanol and Extracellular Dopamine Concentrations in the Nucleus Accumbens After a Single Intraperitoneal Injection

    Hyeon Joo Yim;Donita L. Robinson;Martha L. White;Jason N. Jaworski

  • GABAergic transmission modulates ethanol excitation of ventral tegmental area dopamine neurons.

    Jonathan W. Theile;Hitoshi Morikawa;Rueben A. Gonzales;Richard A. Morrisett

  • Effects of ethanol on stimulated inositol phospholipid hydrolysis in rat brain.

    R. A. Gonzales;C. Theiss;F. T. Crews

  • The shell of the nucleus accumbens has a higher dopamine response compared with the core after non-contingent intravenous ethanol administration.

    E. C. Howard;C. J. Schier;J. S. Wetzel;Christine L Duvauchelle

  • Receptor-gated ion channels may be selective CNS targets for ethanol.

    Unknown

  • κ-Opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration

    William M. Doyon;Elaina C. Howard;Toni S. Shippenberg;Rueben A. Gonzales

  • Effect of gender and estrous cycle on the pharmacokinetics of ethanol in the rat brain.

    Donita L. Robinson;Lane J. Brunner;Rueben A. Gonzales

Frequent Co-Authors

Timothy J Schallert
Timothy J Schallert The University of Texas at Austin
Richard A. Morrisett
Richard A. Morrisett The University of Texas at Austin
Patrick K. Randall
Patrick K. Randall Medical University of South Carolina
Marie H. Monfils
Marie H. Monfils The University of Texas at Austin
W. Todd Maddox
W. Todd Maddox The University of Texas at Austin
John J. Woodward
John J. Woodward Medical University of South Carolina
Colin Sumners
Colin Sumners University of Florida
George R. Uhl
George R. Uhl University of Maryland, Baltimore
Allen A. Fienberg
Allen A. Fienberg Rockefeller University
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute

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