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Immunology

D-Index
65
Citations
23783
World Ranking
2803
National Ranking
1324

Overview

Catherine C. Hedrick is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research primarily spans the fields of immunology and microbiology, with significant contributions to medicine. The scientist's work focuses on several subfields including immunology, molecular biology, oncology, infectious diseases, and neurology.

The research topics covered by Hedrick feature diverse aspects of immune system function and pathology. Key areas include:

  • Immune cells in cancer
  • Atherosclerosis and cardiovascular diseases
  • Immune cell function and interaction
  • Single-cell and spatial transcriptomics
  • Neutrophil, myeloperoxidase and oxidative mechanisms
  • T-cell and B-cell immunology
  • CAR-T cell therapy research

Their recent publications highlight a focus on both cancer immunology and cardiovascular diseases. Notable papers include:

  • Neutrophils in cancer: heterogeneous and multifaceted (2021), Nature Reviews Immunology
  • Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas (2020), Circulation Research
  • Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment (2021), Nature Communications
  • M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer (2020), Journal for ImmunoTherapy of Cancer
  • Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B 100-Reactive CD4 + T-Regulatory Cells (2020), Circulation

Frequent collaborators in Hedrick's work include:

  • Klaus Ley
  • Coleen A. McNamara
  • Ahmad Alimadadi
  • Huy Q. Dinh
  • Yanal Ghosheh

The scientist has published extensively in several academic venues, with repeated contributions to:

  • The Journal of Immunology (13 publications)
  • Cancer Research (8 publications)
  • Journal of Leukocyte Biology (6 publications)
  • Circulation (5 publications)
  • Frontiers in Immunology (5 publications)

In addition to journal articles, Hedrick has contributed to academic books. One such publication is titled Atherosclerosis, published by Springer Science+Business Media in 2022.

Best Publications

  • Understanding the tumor immune microenvironment (TIME) for effective therapy.

    Mikhail Binnewies;Edward W. Roberts;Kelly Kersten;Vincent Chan

  • Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal.

    Leo M. Carlin;Efstathios G. Stamatiades;Cedric Auffray;Richard N. Hanna

  • The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes.

    Richard N Hanna;Leo M Carlin;Harper G Hubbeling;Dominika Nackiewicz

  • Neutrophils in cancer: heterogeneous and multifaceted.

    Catherine C. Hedrick;Ilaria Malanchi

  • Monocyte and Macrophage Dynamics During Atherogenesis

    Klaus Ley;Yury I. Miller;Catherine C. Hedrick

  • Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium

    Ingo Hilgendorf;Louisa M.S. Gerhardt;Timothy C. Tan;Carla Winter

  • Monocyte heterogeneity and functions in cancer

    Claire E. Olingy;Huy Q. Dinh;Catherine C. Hedrick

  • Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry

    Holger Winkels;Erik Ehinger;Melanie Vassallo;Konrad Buscher

  • Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

    Xuchu Que;Ming Yow Hung;Ming Yow Hung;Calvin Yeang;Ayelet Gonen

  • NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

    Richard N. Hanna;Iftach Shaked;Harper G. Hubbeling;Jennifer A. Punt

  • Patrolling monocytes control tumor metastasis to the lung

    Richard N. Hanna;Caglar Cekic;Duygu Sag;Robert Tacke

  • Neutrophils: New insights and open questions

    Klaus Ley;Klaus Ley;Hal M. Hoffman;Paul Kubes;Marco A. Cassatella

  • Nonclassical Monocytes in Health and Disease

    Prakash Babu Narasimhan;Paola Marcovecchio;Anouk A.J. Hamers;Catherine C. Hedrick

  • Nonclassical Patrolling Monocyte Function in the Vasculature

    Graham Thomas;Robert Tacke;Catherine C. Hedrick;Richard N. Hanna

  • Role for Peroxisome Proliferator-Activated Receptor α in Oxidized Phospholipid–Induced Synthesis of Monocyte Chemotactic Protein-1 and Interleukin-8 by Endothelial Cells

    Hans Lee;Weibin Shi;Peter Tontonoz;Peter Tontonoz;Shirley Wang

  • Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas.

    Alma Zernecke;Holger Winkels;Clément Cochain;Jesse W. Williams

  • Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages

    Jeniter E. Hughes;Suseela Srinivasan;Kevin R. Lynch;Richard L. Proia

  • IL-10–producing NKT10 cells are a distinct regulatory invariant NKT cell subset

    Duygu Sag;Petra Krause;Catherine C. Hedrick;Mitchell Kronenberg

  • Overexpression of apolipoprotein AII in transgenic mice converts high density lipoproteins to proinflammatory particles.

    L W Castellani;M Navab;B J Van Lenten;C C Hedrick

  • The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity

    Duygu Sag;Caglar Cekic;Runpei Wu;Joel Linden

  • Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow.

    Yanfang Peipei Zhu;Lindsey Padgett;Huy Q. Dinh;Paola Marcovecchio

Frequent Co-Authors

Klaus Ley
Klaus Ley Augusta University
Pandurangan Vijayanand
Pandurangan Vijayanand La Jolla Institute For Allergy & Immunology
Christopher K. Glass
Christopher K. Glass University of California, San Diego
John S. Parks
John S. Parks Wake Forest University
Jerry L. Nadler
Jerry L. Nadler New York Medical College
Christian H. Ottensmeier
Christian H. Ottensmeier University of Southampton
Christoph J. Binder
Christoph J. Binder Medical University of Vienna
Yury I. Miller
Yury I. Miller University of California, San Diego
Michael J. Thomas
Michael J. Thomas Medical College of Wisconsin
Judith A. Berliner
Judith A. Berliner University of California, Los Angeles

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