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Immunology

D-Index
74
Citations
37354
World Ranking
2021
National Ranking
18

Overview

Lai Guan Ng is affiliated with the Shanghai Immune Therapy Institute in China and conducts research mainly in the fields of immunology, microbiology, medicine, and molecular biology. Their work spans several specialized subfields including immunology, molecular biology, oncology, epidemiology, and cancer research.

The scientist's research covers a range of topics primarily focused on immune cells and their functions, including:

  • Immune cells in cancer
  • Neutrophil, myeloperoxidase and oxidative mechanisms
  • Immune response and inflammation
  • Single-cell and spatial transcriptomics
  • Immune cell function and interaction
  • Immunotherapy and immune responses
  • Neuroinflammation and neurodegeneration mechanisms

Lai Guan Ng has published extensively in several high-profile scientific journals. The frequent venues for their publications include:

  • Nature
  • Immunity
  • Cell
  • hLife
  • Science Immunology

Some notable recent papers illustrating the scope and focus of their research are:

  • "Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19," 2020, published in Cell
  • "A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart," 2020, published in Cell
  • "Co-option of Neutrophil Fates by Tissue Environments," 2020, published in Cell
  • "Deciphering human macrophage development at single-cell resolution," 2020, published in Nature
  • "Patients with COVID-19: in the dark-NETs of neutrophils," 2021, published in Cell Death and Differentiation

The scientist collaborates frequently with a group of co-authors showing multiple joint publications. Frequent co-authors include:

  • Immanuel Kwok
  • Florent Ginhoux
  • Yingrou Tan
  • Andrés Hidalgo
  • Jinmiao Chen

Best Publications

  • Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

    Florent Ginhoux;Florent Ginhoux;Melanie Greter;Marylene Leboeuf;Sayan Nandi

  • The gut microbiota influences blood-brain barrier permeability in mice

    Viorica Braniste;Maha Al-Asmakh;Czeslawa Kowal;Farhana Anuar

  • C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

    Guillaume Hoeffel;Jinmiao Chen;Yonit Lavin;Donovan Low

  • Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

    Svetoslav Chakarov;Hwee Ying Lim;Leonard Tan;Sheau Yng Lim

  • IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

    Andreas Schlitzer;Naomi McGovern;Pearline Teo;Teresa Zelante

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

    Guillaume Hoeffel;Yilin Wang;Melanie Greter;Peter See

  • Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19.

    Aymeric Silvin;Nicolas Chapuis;Garett Dunsmore;Anne-Gaëlle Goubet

  • Heterogeneity of neutrophils

    Lai Guan Ng;Renato Ostuni;Andrés Hidalgo;Andrés Hidalgo

  • Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells.

    Zhaoyuan Liu;Yaqi Gu;Svetoslav Chakarov;Camille Bleriot

  • Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions.

    Maximilien Evrard;Immanuel W.H. Kwok;Immanuel W.H. Kwok;Shu Zhen Chong;Karen W.W. Teng

  • A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

    José A. Nicolás-Ávila;Ana V. Lechuga-Vieco;Lorena Esteban-Martínez;María Sánchez-Díaz

  • B Cell-Activating Factor Belonging to the TNF Family (BAFF)-R Is the Principal BAFF Receptor Facilitating BAFF Costimulation of Circulating T and B Cells

    Lai Guan Ng;Andrew P. R. Sutherland;Rebecca Newton;Fang Qian

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

    Unknown

  • Co-option of Neutrophil Fates by Tissue Environments.

    Iván Ballesteros;Andrea Rubio-Ponce;Marco Genua;Eleonora Lusito

  • Deciphering human macrophage development at single-cell resolution

    Zhilei Bian;Yandong Gong;Tao Huang;Christopher Z. W. Lee;Christopher Z. W. Lee

  • A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

    Jose M Adrover;Carlos del Fresno;Georgiana Crainiciuc;Maria Isabel Cuartero

  • Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

    Hwee Ying Lim;Sheau Yng Lim;Chek Kun Tan;Chung Hwee Thiam

  • Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

    Kazuyuki Takata;Kazuyuki Takata;Tatsuya Kozaki;Christopher Zhe Wei Lee;Morgane Sonia Thion

  • B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.

    Svetlana Shulga-Morskaya;Max Dobles;Meghan E. Walsh;Lai Guan Ng

  • Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection

    Arby Abtin;Rohit Jain;Andrew J Mitchell;Ben Roediger

  • Cutaneous immunosurveillance by self-renewing dermal γδ T cells

    Nital Sumaria;Ben Roediger;Lai Guan Ng;Jim Qin

  • DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling

    Orna Tal;Hwee Ying Lim;Irina Gurevich;Idan Milo

Frequent Co-Authors

Wolfgang Weninger
Wolfgang Weninger Medical University of Vienna
Florent Ginhoux
Florent Ginhoux Agency for Science, Technology and Research
Bin Liu
Bin Liu National University of Singapore
Ben Zhong Tang
Ben Zhong Tang Chinese University of Hong Kong, Shenzhen
Laurent Rénia
Laurent Rénia Nanyang Technological University
Benoit Malleret
Benoit Malleret National University of Singapore
Michael Poidinger
Michael Poidinger Murdoch Children's Research Institute
Andrés Hidalgo
Andrés Hidalgo Yale University
Anis Larbi
Anis Larbi Agency for Science, Technology and Research
Evan W. Newell
Evan W. Newell Fred Hutchinson Cancer Research Center

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