World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
78
Citations
27275
World Ranking
1258
National Ranking
560

Overview

Evan W. Newell is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research spans multiple disciplines, primarily focusing on Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these broader fields, Newell's work often touches on Immunology, Oncology, Molecular Biology, Infectious Diseases, and Public Health, Environmental and Occupational Health.

The scientist's research delves into several specific topics, including:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Single-cell and spatial transcriptomics
  • T-cell and B-cell Immunology
  • Immune cells in cancer

Newell has contributed to the scientific literature through multiple publications in key venues such as bioRxiv (Cold Spring Harbor Laboratory), Regular and Young Investigator Award Abstracts, Blood, The Journal of Immunology, and Zenodo (CERN European Organization for Nuclear Research).

Notable recent papers authored or co-authored by Newell include:

  • Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans, 2020, Nature Immunology
  • SARS-CoV-2-specific CD8+ T cell responses in convalescent COVID-19 individuals, 2021, Journal of Clinical Investigation
  • Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor, 2020, Immunity
  • Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety, 2022, Cancer Discovery
  • A subset of Kupffer cells regulates metabolism through the expression of CD36, 2021, Immunity

Frequent co-authors who have collaborated extensively with Newell include M. Juliana McElrath, Heeju Ryu, Yannick Simoni, Shamin Li, and Stephen C. De Rosa.

Best Publications

  • Dimensionality reduction for visualizing single-cell data using UMAP.

    Etienne Becht;Leland McInnes;John Healy;Charles-Antoine Dutertre

  • Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

    Yannick Simoni;Etienne Becht;Michael Fehlings;Chiew Yee Loh

  • Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species.

    Martin Guilliams;Martin Guilliams;Charles-Antoine Dutertre;Charles-Antoine Dutertre;Charlotte L. Scott;Naomi McGovern

  • Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions.

    Maximilien Evrard;Immanuel W.H. Kwok;Immanuel W.H. Kwok;Shu Zhen Chong;Karen W.W. Teng

  • Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8+ T Cell Phenotypes

    Evan W. Newell;Natalia Sigal;Sean C. Bendall;Garry P. Nolan

  • Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow

    Andreas Schlitzer;V Sivakamasundari;Jinmiao Chen;Hermi Rizal Bin Sumatoh

  • TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity

    Johannes B. Huppa;Markus Axmann;Manuel A. Mörtelmaier;Manuel A. Mörtelmaier;Manuel A. Mörtelmaier;Björn F. Lillemeier;Björn F. Lillemeier

  • Mapping the human DC lineage through the integration of high-dimensional techniques

    Peter See;Charles-Antoine Dutertre;Charles-Antoine Dutertre;Jinmiao Chen;Patrick Günther

  • Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

    Charles Antoine Dutertre;Charles Antoine Dutertre;Etienne Becht;Sergio Erdal Irac;Sergio Erdal Irac;Ahad Khalilnezhad;Ahad Khalilnezhad

  • Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

    Yannick Simoni;Michael Fehlings;Henrik N. Kløverpris;Naomi McGovern

  • High-dimensional analysis of the murine myeloid cell system.

    Burkhard Becher;Andreas Schlitzer;Jinmiao Chen;Florian Mair

  • High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

    Matthew M. Gubin;Ekaterina Esaulova;Ekaterina Esaulova;Jeffrey P. Ward;Olga N. Malkova

  • A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory.

    Leo Swadling;Stefania Capone;Richard D. Antrobus;Anthony Brown

  • Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

    Kazuyuki Takata;Kazuyuki Takata;Tatsuya Kozaki;Christopher Zhe Wei Lee;Morgane Sonia Thion

  • Cytofkit: A Bioconductor Package for an Integrated Mass Cytometry Data Analysis Pipeline.

    Hao Chen;Mai Chan Lau;Michael Thomas Wong;Evan W. Newell

  • Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

    Marco Lepore;Artem Kalinicenko;Alessia Colone;Bhairav Paleja

  • Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

    Wong Yu;Ning Jiang;Peter J.R. Ebert;Brian A. Kidd

  • CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages

    Joannah R. Fergusson;Kira E. Smith;Vicki M. Fleming;Neil Rajoriya

  • Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

    Bertram Bengsch;Takuya Ohtani;Omar Khan;Manu Setty

  • Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.

    Giovanni Galletti;Gabriele De Simone;Emilia M C Mazza;Simone Puccio

  • Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization

    Evan W Newell;Natalia Sigal;Nitya Nair;Brian A Kidd

Frequent Co-Authors

Mark M. Davis
Mark M. Davis Stanford University
Florent Ginhoux
Florent Ginhoux Agency for Science, Technology and Research
Michael G. Fehlings
Michael G. Fehlings University of Toronto
Charles-Antoine Dutertre
Charles-Antoine Dutertre Institut Gustave Roussy
Anis Larbi
Anis Larbi Agency for Science, Technology and Research
Antonio Bertoletti
Antonio Bertoletti Duke NUS Graduate Medical School
Michael Poidinger
Michael Poidinger Murdoch Children's Research Institute
Andreas Schlitzer
Andreas Schlitzer University of Bonn
Lai Guan Ng
Lai Guan Ng Westlake University
Benoit Malleret
Benoit Malleret National University of Singapore

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