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Immunology
Singapore
2026

D-Index & Metrics

Immunology

D-Index
140
Citations
97946
World Ranking
160
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Immunology in Singapore Leader Award
  • 2025 - Research.com Immunology in Singapore Leader Award
  • 2022 - Research.com Immunology in Singapore Leader Award

Overview

Florent Ginhoux is affiliated with the Agency for Science, Technology and Research in Singapore. Their research spans several fields primarily within the life sciences, focusing on immunology, microbiology, and molecular biology. The scientist has an extensive publication record across various specialized subfields, including immunology, molecular biology, neurology, oncology, and physiology.

The scientific work concentrates on topics such as immune cells in cancer, neuroinflammation and neurodegeneration mechanisms, immune cell function and interaction, immunotherapy and immune responses, single-cell and spatial transcriptomics, T-cell and B-cell immunology, and immune responses and vaccinations.

Florent Ginhoux has contributed to numerous scientific papers published in prominent venues. Some recent examples include:

  • "Microglia states and nomenclature: A field at its crossroads" (2022, Neuron)
  • "Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer" (2022, Nature Communications)
  • "A single-cell and spatially resolved atlas of human breast cancers" (2021, Nature Genetics)
  • "Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19" (2020, Cell)
  • "Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma" (2020, Cell)

Frequent co-authors who have collaborated extensively with Florent Ginhoux include:

  • Zhaoyuan Liu
  • Charles-Antoine Dutertre
  • Camille Blériot
  • Aymeric Silvin
  • Jerry Kok Yen Chan

Their publications have appeared repeatedly in a set of well-known scientific venues. The most common are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Cell
  • Nature Communications
  • Nature Immunology

Florent Ginhoux's research areas focus on understanding immune system behavior and its role in cancer and neurological diseases, employing techniques such as single-cell and spatial transcriptomics. This work integrates multiple disciplines to explore cellular interactions in health and disease on a molecular and cellular level.

Best Publications

  • Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

    Florent Ginhoux;Florent Ginhoux;Melanie Greter;Marylene Leboeuf;Sayan Nandi

  • Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

    Marie Vétizou;Marie Vétizou;Marie Vétizou;Jonathan M. Pitt;Jonathan M. Pitt;Jonathan M. Pitt;Romain Daillère;Romain Daillère;Romain Daillère;Patricia Lepage

  • Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

    Daigo Hashimoto;Andrew Chow;Andrew Chow;Clara Noizat;Clara Noizat;Pearline Teo

  • Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.

    Timothy R. Hammond;Timothy R. Hammond;Timothy R. Hammond;Connor Dufort;Lasse Dissing-Olesen;Lasse Dissing-Olesen;Lasse Dissing-Olesen;Stefanie Giera;Stefanie Giera

  • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

    Sophie Viaud;Sophie Viaud;Fabiana Saccheri;Grégoire Mignot;Takahiro Yamazaki

  • Monocytes and macrophages: developmental pathways and tissue homeostasis

    Florent Ginhoux;Steffen Jung

  • Microglia states and nomenclature: A field at its crossroads

    Unknown

  • Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny

    Martin Guilliams;Florent Ginhoux;Claudia Jakubzick;Shalin H. Naik

  • Tissue-Resident Macrophage Ontogeny and Homeostasis.

    Florent Ginhoux;Florent Ginhoux;Martin Guilliams

  • Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

    Diego Adhemar Jaitin;Lorenz Adlung;Christoph A. Thaiss;Assaf Weiner

  • Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

    Hélène Salmon;Juliana Idoyaga;Adeeb Rahman;Marylène Leboeuf

  • Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Franziska Paul;Yaâara Arkin;Amir Giladi;Diego Adhemar Jaitin

  • C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

    Guillaume Hoeffel;Jinmiao Chen;Yonit Lavin;Donovan Low

  • Origin and differentiation of microglia.

    Florent Ginhoux;Shawn Lim;Guillaume Hoeffel;Donovan Low

  • Origin of the lamina propria dendritic cell network.

    Milena Bogunovic;Florent Ginhoux;Julie Helft;Limin Shang

  • Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells

    Miriam Merad;Florent Ginhoux;Matthew Collin;Matthew Collin

  • Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

    Svetoslav Chakarov;Hwee Ying Lim;Leonard Tan;Sheau Yng Lim

  • IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

    Andreas Schlitzer;Naomi McGovern;Pearline Teo;Teresa Zelante

  • Minimal Differentiation of Classical Monocytes as They Survey Steady-State Tissues and Transport Antigen to Lymph Nodes

    Claudia Jakubzick;Claudia Jakubzick;Emmanuel L. Gautier;Sophie L. Gibbings;Dorothy K. Sojka

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Langerhans cells arise from monocytes in vivo

    Florent Ginhoux;Frank Tacke;Veronique Angeli;Milena Bogunovic

  • Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

    Guillaume Hoeffel;Yilin Wang;Melanie Greter;Peter See

  • The origin and development of nonlymphoid tissue CD103+ DCs

    Florent Ginhoux;Kang Liu;Julie Helft;Milena Bogunovic

Frequent Co-Authors

Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Andreas Schlitzer
Andreas Schlitzer University of Bonn
Matthew Collin
Matthew Collin Newcastle University
Lai Guan Ng
Lai Guan Ng Westlake University
Charles-Antoine Dutertre
Charles-Antoine Dutertre Institut Gustave Roussy
Muzlifah Haniffa
Muzlifah Haniffa Newcastle University
Michael Poidinger
Michael Poidinger Murdoch Children's Research Institute
Evan W. Newell
Evan W. Newell Fred Hutchinson Cancer Research Center
Anis Larbi
Anis Larbi Agency for Science, Technology and Research
Benoit Malleret
Benoit Malleret National University of Singapore

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