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Chemistry

D-Index
59
Citations
12802
World Ranking
10110
National Ranking
2813

Research.com Recognitions

  • 2013 - Fellow of the American Chemical Society
  • 1996 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Gunda I. Georg is affiliated with the University of Minnesota in the United States. Their research spans multiple fields including history and philosophy of science, molecular biology, genetics, oncology, and public health, environmental and occupational health.

Their recent scholarly contributions include these papers:

  • Artificial Intelligence in Drug Discovery: Into the Great Wide Open, 2020, Journal of Medicinal Chemistry
  • The Na+ and K+ transport system of sperm (ATP1A4) is essential for male fertility and an attractive target for male contraception, 2020, Biology of Reproduction
  • Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding, 2023, Nature Communications
  • Retinoic acid receptor antagonists for male contraception: current status, 2020, Biology of Reproduction
  • TSSK3, a novel target for male contraception, is required for spermiogenesis, 2021, Molecular Reproduction and Development

Key topics covered in their body of work include:

  • Academic Writing and Publishing
  • Cancer-related Molecular Pathways
  • Health Sciences Research and Education
  • Estrogen and related hormone effects
  • Sperm and Testicular Function
  • Retinoids in leukemia and cellular processes
  • Reproductive Biology and Fertility

Frequent co-authors with whom Georg has collaborated include:

  • Shaomeng Wang
  • Craig W. Lindsley
  • Cynthia J. Burrows
  • Shu Wang
  • Hyun Jae Kim

Publications tend to appear in specialized journals with multiple contributions to:

  • Journal of Medicinal Chemistry
  • ACS Medicinal Chemistry Letters
  • Biology of Reproduction
  • Cancer Research
  • ChemMedChem

Georg has been recognized by professional societies, including being named a Fellow of the American Chemical Society in 2013 and a Fellow of the American Association for the Advancement of Science (AAAS) in 1996. These honors indicate professional recognition within the scientific community.

Best Publications

  • The Ecstasy and Agony of Assay Interference Compounds

    Courtney Aldrich;Carolyn Bertozzi;Gunda I. Georg;Laura Kiessling

  • A convenient method for the efficient removal of ruthenium byproducts generated during olefin metathesis reactions.

    Yu Mi Ahn;Kyoung Lang Yang;Gunda I. Georg

  • A Preclinical Evaluation of Minnelide as a Therapeutic Agent Against Pancreatic Cancer

    Rohit Chugh;Veena Sangwan;Satish P. Patil;Vikas Dudeja

  • Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R,3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-.beta.-lactams through chiral ester enolate-imine cyclocondensation

    Iwao Ojima;Ivan Habus;Mangzhu Zhao;Gunda I. Georg

  • Mild and selective hydrozirconation of amides to aldehydes using Cp2Zr(H)Cl: scope and mechanistic insight.

    Jared T. Spletstoser;Jonathan M. White;and Ashok Rao Tunoori;Gunda I. Georg

  • Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors.

    Stuart W.J. Ember;Jin Yi Zhu;Sanne H. Olesen;Mathew P. Martin

  • Taxane Anticancer Agents Basic Science and Current Status

    Gunda I. Georg;Thomas T. Chen;Iwao Ojima;Dolatrai M. Vyas

  • Discovery of a Potential Allosteric Ligand Binding Site in CDK2.

    Stephane Betzi;Riazul Alam;Mathew Martin;Donna J. Lubbers

  • Hydrophobic collapse of taxol and taxotere solution conformations in mixtures of water and organic solvent

    D. G. Vander Velde;G. I. Georg;G. L. Grunewald;C. W. Gunn

  • Palladium(II)-catalyzed direct arylation of enaminones using organotrifluoroborates.

    Haibo Ge;Micah J. Niphakis;Gunda I. Georg

  • A Novel and Expeditious Reduction of Tertiary Amides to Aldehydes Using Cp2Zr(H)Cl

    Jonathan M. White;and Ashok Rao Tunoori;Gunda I. Georg

  • Synthesis of biologically active taxol analogues with modified phenylisoserine side chains.

    Gunda I. Georg;Zacharia S. Cheruvallath;Richard H. Himes;Magdalena R. Mejillano

  • Cyclin-dependent kinase inhibitor dinaciclib interacts with the acetyl-lysine recognition site of bromodomains.

    Mathew P. Martin;Sanne H. Olesen;Gunda I. Georg;Ernst Schönbrunn

  • Asymmetric synthesis of (1′R,3R,4R)-4-acetoxy-3-(1′-((tert-butyldimethylsilyl)oxy)ethyl)-2- azetidinone and other 3-(1′-Hydroxyethyl)-2-azetidinones from (S)-(+)-Ethyl 3-hydroxybutanoate: Formal total synthesis of (+)-thienamycin

    Gunda I. Georg;Joydeep Kant;Harpal S. Gill

  • Epothilone and paclitaxel: unexpected differences in promoting the assembly and stabilization of yeast microtubules.

    Claudia J. Bode;Mohan L. Gupta;Emily A. Reiff;Kathy A. Suprenant

  • Water-soluble medicaments of hindered phenols

    Stella Valentino J;Zygmunt Jan J;Georg Ingrid Gunda;Safadi Muhammed S

  • The cryptophycins: their synthesis and anticancer activity.

    MariJean Eggen;Gunda I. Georg

  • Polymer-bound triphenylphosphine as traceless reagent for mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols and alcohols

    Ashok Rao Tunoori;Dinah Dutta;Gunda I. Georg

  • Gamendazole, an Orally Active Indazole Carboxylic Acid Male Contraceptive Agent, Targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and Stimulates Il1a Transcription in Rat Sertoli Cells

    Joseph S. Tash;Ramappa Chakrasali;Sudhakar R. Jakkaraj;Jennifer Hughes

  • β-Amyloid-Induced Neurodegeneration and Protection by Structurally Diverse Microtubule-Stabilizing Agents

    Mary L. Michaelis;Sabah Ansar;Yingxue Chen;Emily R Reiff

  • Novel prodrug approach for tertiary amines: synthesis and preliminary evaluation of N-phosphonooxymethyl prodrugs.

    Jeffrey P. Krise;Jan Zygmunt;Gunda I. Georg;Valentino J. Stella

  • Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action

    Suzanne B. Buck;Sam F. Victory;Richard H. Himes;Gunda I. Georg

Frequent Co-Authors

Dennis C. Liotta
Dennis C. Liotta Emory University
Alanna Schepartz
Alanna Schepartz University of California, Berkeley
Craig W. Lindsley
Craig W. Lindsley Vanderbilt University
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Kenneth M. Merz
Kenneth M. Merz Michigan State University
Prashant V. Kamat
Prashant V. Kamat University of Notre Dame
Marc A. Hillmyer
Marc A. Hillmyer University of Minnesota
Vincent M. Rotello
Vincent M. Rotello University of Massachusetts Amherst
Gregory D. Scholes
Gregory D. Scholes Princeton University

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