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D-Index & Metrics

Chemistry

D-Index
63
Citations
11249
World Ranking
8628
National Ranking
2468

Biology and Biochemistry

D-Index
64
Citations
11355
World Ranking
9894
National Ranking
4333

Research.com Recognitions

  • 2014 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Academy of Arts and Sciences
  • 2010 - Fellow of the American Chemical Society
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Alanna Schepartz is affiliated with the University of California, Berkeley, in the United States. Their research spans multiple fields within biochemistry, genetics, and molecular biology, with a prolific output focusing primarily on molecular biology. They have contributed significantly to subfields such as history and philosophy of science, cell biology, genetics, and biophysics.

The body of work also extensively addresses key topics including academic writing and publishing, RNA and protein synthesis mechanisms, RNA modifications and cancer, chemical synthesis and analysis, RNA research and splicing, RNA interference and gene delivery, and advanced fluorescence microscopy techniques.

Frequent collaborators in Schepartz's research include Scott J. Miller, Cynthia J. Burrows, Shu Wang, Hyun Jae Kim, and Gerald J. Meyer.

Schepartz's recent papers demonstrate a range of topics and interdisciplinary approaches:

  • Structure of the bacterial ribosome at 2 Å resolution, 2020, eLife
  • Extremely Bright, Near-IR Emitting Spontaneously Blinking Fluorophores Enable Ratiometric Multicolor Nanoscopy in Live Cells, 2021, ACS Central Science
  • Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons, 2021, ACS Chemical Biology
  • Bioorthogonal, Fluorogenic Targeting of Voltage-Sensitive Fluorophores for Visualizing Membrane Potential Dynamics in Cellular Organelles, 2022, Journal of the American Chemical Society
  • Long-term super-resolution inner mitochondrial membrane imaging with a lipid probe, 2023, Nature Chemical Biology

Key publication venues where Schepartz has frequently published include bioRxiv (Cold Spring Harbor Laboratory), ACS Central Science, Biochemistry, Journal of the American Chemical Society, and Nature Chemistry.

The scientist has received multiple recognitions, including membership in the National Academy of Sciences in 2014. Other honors include fellowships with the American Academy of Arts and Sciences, the American Chemical Society, the American Association for the Advancement of Science (AAAS), and the Alfred P. Sloan Foundation.

Best Publications

  • Helical beta-peptide inhibitors of the p53-hDM2 interaction.

    Joshua A. Kritzer;James D. Lear;Michael E. Hodsdon;Alanna Schepartz

  • The Ecstasy and Agony of Assay Interference Compounds

    Courtney Aldrich;Carolyn Bertozzi;Gunda I. Georg;Laura Kiessling

  • High-Resolution Structure of a β-Peptide Bundle

    Douglas S. Daniels;E. James Petersson;Jade X. Qiu;Alanna S. Schepartz

  • β-Peptides as inhibitors of protein–protein interactions

    Joshua A. Kritzer;Olen M. Stephens;Danielle A. Guarracino;Samuel K. Reznik

  • Inhibiting HIV Fusion with a β-Peptide Foldamer

    Olen M. Stephens;Sunghwan Kim;Brett D. Welch;Michael E. Hodsdon

  • Two-colour live-cell nanoscale imaging of intracellular targets

    Francesca Bottanelli;Emil B. Kromann;Edward S. Allgeyer;Roman S. Erdmann

  • Selective recognition of protein tetraserine motifs with a cell-permeable, pro-fluorescent bis-boronic acid.

    Tiffany L. Halo;Jacob Appelbaum;Elissa M. Hobert;Daniel M. Balkin

  • Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax

    Anne M. Baranger;C. Rodgers Palmer;Mary Kay Hamm;Holli A. Giebler

  • Long time-lapse nanoscopy with spontaneously blinking membrane probes

    Hideo Takakura;Yongdeng Zhang;Roman S Erdmann;Alexander D Thompson

  • Arginine Topology Controls Escape of Minimally Cationic Proteins from Early Endosomes to the Cytoplasm

    Jacob S. Appelbaum;Jonathan R. LaRochelle;Betsy A. Smith;Daniel M. Balkin

  • Conformation-dependent cleavage of staphylococcal nuclease with a disulfide-linked iron chelate

    Mario R. Ermacora;Jose M. Delfino;Bernard Cuenoud;Alanna Schepartz

  • Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH

    Nathan W Luedtke;Rachel J Dexter;Daniel B Fried;Alanna Schepartz

  • Altered specificity of DNA-binding proteins with transition metal dimerization domains

    Bernard Cuenoud;Alanna Schepartz

  • Super-resolution imaging of the Golgi in live cells with a bioorthogonal ceramide probe.

    Roman S. Erdmann;Hideo Takakura;Alexander D. Thompson;Felix Rivera-Molina

  • Highly Specific DNA Recognition by a Designed Miniature Protein

    Neal J. Zondlo;Alanna Schepartz

  • Labeling Strategies Matter for Super-Resolution Microscopy: A Comparison between HaloTags and SNAP-tags.

    Roman S. Erdmann;Stephanie Wood Baguley;Jennifer H. Richens;Rebecca F. Wissner

  • Sophistication of foldamer form and function in vitro and in vivo.

    Arjel D Bautista;Cody J Craig;Elizabeth A Harker;Alanna Schepartz

  • Helix macrodipole control of β3-peptide 14-helix stability in water

    Scott A. Hart;Adilah B. F. Bahadoor;Erin E. Matthews;Xiaoyan J. Qiu

  • Site-Specific Cleavage of the Protein Calmodulin Using a Trifluoperazine-Based Affinity Reagent

    Alanna Schepartz;Bernard Cuenoud

  • Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif.

    Douglas S. Daniels;Alanna Schepartz

  • Design and Evolution of a Miniature Bcl-2 Binding Protein.

    Jason W. Chin;Alanna Schepartz

Frequent Co-Authors

Gunda I. Georg
Gunda I. Georg University of Minnesota
Scott J. Miller
Scott J. Miller Yale University
Dennis C. Liotta
Dennis C. Liotta Emory University
Craig W. Lindsley
Craig W. Lindsley Vanderbilt University
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
William L. Jorgensen
William L. Jorgensen Yale University
Kenneth M. Merz
Kenneth M. Merz Michigan State University
Jonathan V. Sweedler
Jonathan V. Sweedler University of Illinois at Urbana-Champaign
Paul S. Weiss
Paul S. Weiss University of California, Los Angeles

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