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Chemistry

D-Index
113
Citations
51078
World Ranking
703
National Ranking
288

Research.com Recognitions

  • 2014 - Member of the National Academy of Sciences
  • 2014 - Fellow, National Academy of Inventors
  • 2010 - Fellow of the American Academy of Arts and Sciences
  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1993 - Fellow of Alfred P. Sloan Foundation

Overview

Samuel H. Gellman is affiliated with the University of Wisconsin-Madison in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with additional significant contributions in the fields of medicine, molecular biology, organic chemistry, epidemiology, infectious diseases, and immunology.

The scientist's work covers topics including:

  • Chemical Synthesis and Analysis
  • Receptor Mechanisms and Signaling
  • Respiratory Viral Infections Research
  • Neuropeptides and Animal Physiology
  • Antimicrobial Peptides and Activities
  • SARS-CoV-2 and COVID-19 Research
  • Click Chemistry and Applications

Frequent publication venues for Samuel H. Gellman comprise:

  • Journal of the American Chemical Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • The Cambridge Structural Database
  • Organic Letters

Some of their recent publications include:

  • Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets, 2021, published in Science
  • Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis, 2022, published in Journal of the American Chemical Society
  • Foldamer Catalysis, 2020, published in Journal of the American Chemical Society
  • Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain, 2020, published in mBio
  • Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation, 2021, published in Science Signaling

They have collaborated frequently with a group of coauthors including Anne Moscona, Matteo Porotto, Victor K. Outlaw, Thomas J. Gardella, and Brian P. Cary.

Samuel H. Gellman has been recognized with several honors, including:

  • Fellow, National Academy of Inventors (2014)
  • Member of the National Academy of Sciences (2014)
  • Fellow of the American Academy of Arts and Sciences (2010)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2005)
  • Fellow of Alfred P. Sloan Foundation (1993)

Best Publications

  • Crystal structure of the β2 adrenergic receptor-Gs protein complex.

    Søren G. F. Rasmussen;Brian T. DeVree;Yaozhong Zou;Andrew C. Kruse

  • Foldamers: A Manifesto

    Samuel H. Gellman

  • beta-Peptides: from structure to function.

    Richard P. Cheng;Samuel H. Gellman;William F. DeGrado

  • Structure of a nanobody-stabilized active state of the β2 adrenoceptor

    Søren G F Rasmussen;Hee Jung Choi;Juan Jose Fung;Els Pardon

  • β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers

    Daniel H. Appella;Laurie A. Christianson;Isabella L. Karle;and Douglas R. Powell

  • Structure and function of an irreversible agonist-β2 adrenoceptor complex

    Daniel M. Rosenbaum;Cheng Zhang;Joseph A. Lyons;Joseph A. Lyons;Ralph Holl

  • Non-haemolytic β-amino-acid oligomers

    Emilie A. Porter;Xifang Wang;Hee-Seung Lee;Bernard Weisblum

  • Residue-based control of helix shape in beta-peptide oligomers.

    Daniel H. Appella;Laurie A. Christianson;Daniel A. Klein;Douglas R. Powell

  • Foldamers with Heterogeneous Backbones

    W. Seth Horne;Samuel H. Gellman

  • Conformation-directing effects of a single intramolecular amide-amide hydrogen bond: variable-temperature NMR and IR studies on a homologous diamide series

    Samuel H. Gellman;Gregory P. Dado;Gui Bai Liang;Bruce R. Adams

  • Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

    Pil Seok Chae;Søren G F Rasmussen;Rohini R. Rana;Kamil Gotfryd

  • Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides.

    Emilie A. Porter;Bernard Weisblum;Samuel H. Gellman

  • Mimicry of antimicrobial host-defense peptides by random copolymers.

    Brendan P. Mowery;Sarah E. Lee;Denis A. Kissounko;Raquel F. Epand

  • Intramolecular nitrene carbon-hydrogen insertions mediated by transition-metal complexes as nitrogen analogs of cytochrome P-450 reactions

    Ronald Breslow;Samuel H. Gellman

  • Minimal model systems for β-sheet secondary structure in proteins

    Samuel H Gellman

  • Rules for Antiparallel β-Sheet Design: d-Pro-Gly Is Superior to l-Asn-Gly for β-Hairpin Nucleation1

    Heather E. Stanger;Samuel H. Gellman

  • Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency.

    Tami L. Raguse;Emilie A. Porter;Bernard Weisblum;Samuel H. Gellman

  • Intramolecular Hydrogen Bonding in Derivatives of .beta.-Alanine and .gamma.-Amino Butyric Acid; Model Studies for the Folding of Unnatural Polypeptide Backbones

    Gregory P. Dado;Samuel H. Gellman

  • Tosylamidation of cyclohexane by a cytochrome P-450 model

    Ronald Breslow;Samuel H. Gellman

  • Cytoplasmic and Nuclear Delivery of a TAT-derived Peptide and a β-Peptide after Endocytic Uptake into HeLa Cells

    Terra B. Potocky;Anant K. Menon;Samuel H. Gellman

  • Stereochemical Requirements for β-Hairpin Formation: Model Studies with Four-Residue Peptides and Depsipeptides

    Tasir S. Haque;Jennifer C. Little;Samuel H. Gellman

Frequent Co-Authors

Ilia A. Guzei
Ilia A. Guzei University of Wisconsin–Madison
Bernard Weisblum
Bernard Weisblum University of Wisconsin–Madison
Shannon S. Stahl
Shannon S. Stahl University of Wisconsin–Madison
Nicholas L. Abbott
Nicholas L. Abbott Cornell University
Timothy S. Zwier
Timothy S. Zwier Purdue University West Lafayette
Erinna F. Lee
Erinna F. Lee La Trobe University
Brian K. Kobilka
Brian K. Kobilka Stanford University
W. Douglas Fairlie
W. Douglas Fairlie La Trobe University
Anne Moscona
Anne Moscona Columbia University
Paul B. Savage
Paul B. Savage Brigham Young University

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