What is he best known for?
The fields of study he is best known for:
- Receptor
- G protein-coupled receptor
- Biochemistry
His main research concerns Receptor, Allosteric regulation, G protein-coupled receptor, Pharmacology and Functional selectivity.
His Receptor research is multidisciplinary, incorporating perspectives in Endocrinology and Signal transduction.
The study incorporates disciplines such as Biophysics, Muscarinic acetylcholine receptor, Stereochemistry and Binding site in addition to Allosteric regulation.
His G protein-coupled receptor study combines topics from a wide range of disciplines, such as Protein structure, Structural biology, Computational biology and Drug discovery.
In general Pharmacology, his work in Clinical pharmacology, Catalytic receptors and Drug classification is often linked to Ligand linking many areas of study.
Arthur Christopoulos works mostly in the field of Functional selectivity, limiting it down to topics relating to Calcium signaling and, in certain cases, Signalling, as a part of the same area of interest.
His most cited work include:
- Fitting models to biological data using linear and nonlinear regression : a practical guide to curve fitting (1590 citations)
- Functional Selectivity and Classical Concepts of Quantitative Pharmacology (907 citations)
- Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders (800 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Receptor, Allosteric regulation, G protein-coupled receptor, Muscarinic acetylcholine receptor and Pharmacology.
His Receptor research focuses on Cell biology and how it relates to Peptide.
His Allosteric regulation research includes themes of Biophysics, Stereochemistry and Cooperativity.
His work is dedicated to discovering how G protein-coupled receptor, Computational biology are connected with Bioinformatics and other disciplines.
Arthur Christopoulos has researched Muscarinic acetylcholine receptor in several fields, including Carbachol, Acetylcholine and Acetylcholine receptor.
His study looks at the intersection of Pharmacology and topics like Muscarinic acetylcholine receptor M1 with Muscarinic acetylcholine receptor M4.
He most often published in these fields:
- Receptor (50.37%)
- Allosteric regulation (46.21%)
- G protein-coupled receptor (34.23%)
What were the highlights of his more recent work (between 2016-2021)?
- Receptor (50.37%)
- G protein-coupled receptor (34.23%)
- Allosteric regulation (46.21%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Receptor, G protein-coupled receptor, Allosteric regulation, Agonist and Muscarinic acetylcholine receptor.
His study in Receptor is interdisciplinary in nature, drawing from both Biophysics, Pharmacology, Peptide and Cell biology.
His G protein-coupled receptor research also works with subjects such as
- Computational biology and related Bioinformatics and Virtual screening,
- Drug discovery and related Small molecule.
His work in the fields of Allosteric regulation, such as Allosteric modulator, overlaps with other areas such as Endogenous agonist.
He combines subjects such as Extracellular and Structure–activity relationship with his study of Agonist.
His Muscarinic acetylcholine receptor research includes themes of Subtype selectivity, Acetylcholine, Acetylcholine receptor and Rational design.
Between 2016 and 2021, his most popular works were:
- THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors (495 citations)
- Phase-plate cryo-EM structure of a class B GPCR–G-protein complex (277 citations)
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors (270 citations)
In his most recent research, the most cited papers focused on:
- Receptor
- G protein-coupled receptor
- Amino acid
His primary scientific interests are in G protein-coupled receptor, Receptor, Functional selectivity, Pharmacology and Agonist.
The various areas that Arthur Christopoulos examines in his G protein-coupled receptor study include Structural biology, G protein, Computational biology, Allosteric regulation and Drug discovery.
He interconnects Protein structure, Biophysics and Function, Cell biology in the investigation of issues within Receptor.
His Functional selectivity research includes elements of Arrestin, Drug development, Calcium signaling, Drug action and Neuroscience.
Partial agonist and Inverse agonist is closely connected to Adenosine receptor in his research, which is encompassed under the umbrella topic of Pharmacology.
The study incorporates disciplines such as Caveolae and Dynamin in addition to Agonist.
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