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Adriaan P. IJzerman

Adriaan P. IJzerman

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Chemistry
Netherlands
2025
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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
32410
World Ranking
2670
National Ranking
66

Chemistry

D-Index
87
Citations
32062
World Ranking
2374
National Ranking
56

Adriaan P. IJzerman publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Adriaan P. IJzerman sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 535 publications — 90th percentile

90% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Adriaan P. IJzerman D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Adriaan P. IJzerman sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 87 D-Index — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Chemistry in Netherlands Leader Award
  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2022 - Research.com Chemistry in Netherlands Leader Award

Overview

Adriaan P. IJzerman is affiliated with Leiden University in the Netherlands, with a primary focus on biochemistry, genetics, and molecular biology. Their research spans various subfields including molecular biology, cellular and molecular neuroscience, physiology, computational theory and mathematics, and oncology.

The scientist's work prominently addresses receptor mechanisms and signaling, particularly adenosine and purinergic signaling. Their research also encompasses computational drug discovery methods, pharmacological receptor mechanisms and effects, neuropeptides and animal physiology, monoclonal and polyclonal antibodies research, and drug transport and resistance mechanisms.

Adriaan P. IJzerman has contributed to multiple recent publications. Notable papers include:

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors (2021, British Journal of Pharmacology)
  • The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors (2023, British Journal of Pharmacology)
  • The Concise Guide to PHARMACOLOGY 2023/24: Ion channels (2023, British Journal of Pharmacology)
  • International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update (2022, Pharmacological Reviews)
  • DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology (2021, Journal of Cheminformatics)

Frequent co-authors collaborating with IJzerman include Laura H. Heitman, Gerard J. P. van Westen, Willem Jespers, Marina Gorostiola González, and Daan van der Es. These collaborations illustrate a network of researchers working closely on related pharmacological topics.

The scientist's research has been published across several well-known venues, with recurrent contributions to the following:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • Biochemical Pharmacology
  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of Cheminformatics
  • British Journal of Pharmacology

Adriaan P. IJzerman's work integrates experimental and computational approaches, bridging molecular insights with pharmacological applications. This interdisciplinary profile is supported by publications addressing both receptor biology and advanced computational methods for drug discovery.

Best Publications

  • International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors

    Bertil B. Fredholm;Adriaan P. IJzerman;Kenneth A. Jacobson;Karl-Norbert Klotz

  • The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist.

    Veli-Pekka Jaakola;Mark T. Griffith;Michael A. Hanson;Vadim Cherezov

  • International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update

    Bertil B. Fredholm;Adriaan P. IJzerman;Kenneth A. Jacobson;Joel Linden

  • Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

    Wei Liu;Eugene Chun;Aaron A. Thompson;Pavel Chubukov

  • Small molecule absorption by PDMS in the context of drug response bioassays

    B.J. van Meer;H. de Vries;K.S.A. Firth;J. van Weerd

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Role of ceramide 1 in the molecular organization of the stratum corneum lipids

    J.A. Bouwstra;G.S. Gooris;F.E.R. Dubbelaar;A.M. Weerheim

  • Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set

    Eelke B. Lenselink;Niels ten Dijke;Brandon Bongers;George Papadatos;George Papadatos

  • Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

    Yi Zheng;Ling Qin;Natalia V. Ortiz Zacarías;Henk de Vries

  • Recent developments in constitutive receptor activity and inverse agonism, and their potential for GPCR drug discovery

    Richard A. Bond;Ad P. IJzerman

  • Structure-Based Discovery of Novel Chemotypes for Adenosine A2A Receptor Antagonists

    Vsevolod Katritch;Vsevolod Katritch;Veli-Pekka Jaakola;Veli-Pekka Jaakola;J. Robert Lane;Judy Lin

  • Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation

    M.C. Peeters;G.J.P. van Westen;Q. Li;A.P. IJzerman

  • Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor

    Kerstin Wieland;Helene M. Zuurmond;Cornelius Krasel;Ad P. Ijzerman

  • Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase.

    B.E. Crack;C.E. Pollard;M.W. Beukers;S.M. Roberts

  • Inverse agonism at G protein‐coupled receptors: (patho)physiological relevance and implications for drug discovery

    Rianne A F De Ligt;Angeliki P Kourounakis;Ad P IJzerman

  • International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)

    Stefan Offermanns;Steven L. Colletti;Timothy W. Lovenberg;Graeme Semple

  • New, non-adenosine, high-potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine.

    Margot W Beukers;Lisa C W Chang;Jacobien K von Frijtag Drabbe Künzel;Thea Mulder-Krieger

  • A Binding Site Model and Structure-Activity Relationships for the Rat A3 Adenosine Receptor

    P J van Galen;A H van Bergen;C Gallo-Rodriguez;N Melman

  • Functional efficacy of adenosine A2A receptor agonists is positively correlated to their receptor residence time

    Dong Guo;Thea Mulder-Krieger;Adriaan P IJzerman;Laura H Heitman

  • Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

    Doris A. Schuetz;Wilhelmus Egbertus Arnout de Witte;Yin Cheong Wong;Bernhard Knasmueller

  • Allosteric modulation of G-protein-coupled receptors

    Ad P IJzerman;Ineke van Wijngaarden;Willem Soudijn

Frequent Co-Authors

Johannes Brussee
Johannes Brussee Leiden University
Meindert Danhof
Meindert Danhof Leiden University
Kenneth A. Jacobson
Kenneth A. Jacobson National Institutes of Health
Andreas Bender
Andreas Bender University of Cambridge
Zhan-Guo Gao
Zhan-Guo Gao National Institutes of Health
Christa E. Müller
Christa E. Müller University of Bonn
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Pier Andrea Borea
Pier Andrea Borea University of Ferrara
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center

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