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Meindert Danhof

Meindert Danhof

D-Index & Metrics

Medicine

D-Index
82
Citations
23210
World Ranking
16193
National Ranking
612

Overview

Meindert Danhof is affiliated with Leiden University in the Netherlands and has contributed to the field of medicine, particularly in genetics, pharmacology, epidemiology, infectious diseases, and clinical biochemistry. Their research spans several interconnected topics including myeloproliferative neoplasms, chronic lymphocytic leukemia, Pneumocystis jirovecii pneumonia detection and treatment, tuberculosis research and epidemiology, drug-induced adverse reactions, antibiotics pharmacokinetics and efficacy, and metabolism and genetic disorders.

Recent publications by Meindert Danhof include:

  • In memoriam Lambertus ("Bert") A. Peletier 29 March 1937-16 December 2023: Furthering quantitative pharmacology through applied mathematics, 2024, CPT Pharmacometrics & Systems Pharmacology

Meindert Danhof has collaborated with co-authors such as:

  • Martin Marinov
  • Diego González
  • Sajid Melvin George
  • Asma Ahmed
  • S. Keeney

Their work has been published in various journals, including:

  • Clinical Lymphoma Myeloma & Leukemia
  • CPT Pharmacometrics & Systems Pharmacology
  • American Journal of Respiratory and Critical Care Medicine
  • Pharmaceutical Research
  • Transplantation

Meindert Danhof's contributions to medicine focus on the following fields of study:

  • Genetics
  • Pharmacology
  • Epidemiology
  • Infectious Diseases
  • Clinical Biochemistry

Main research topics covered include:

  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Tuberculosis Research and Epidemiology
  • Drug-Induced Adverse Reactions
  • Antibiotics Pharmacokinetics and Efficacy
  • Metabolism and Genetic Disorders

Best Publications

  • Buprenorphine induces ceiling in respiratory depression but not in analgesia

    A. Dahan;A. Yassen;R. Romberg;E. Sarton

  • Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats

    A Dahan;A Yassen;H Bijl;R Romberg

  • Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research.

    Meindert Danhof;Elizabeth C.M. de Lange;Oscar E. Della Pasqua;Bart A. Ploeger

  • Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain.

    Elizabeth C.M. de Lange;Meindert Danhof

  • Therapeutic drug monitoring in saliva.

    M. Danhof;D. D. Breimer

  • Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling: Biophase Distribution, Receptor Theory, and Dynamical Systems Analysis

    Meindert Danhof;Joost de Jongh;Elizabeth C M De Lange;Oscar Della Pasqua

  • Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood–brain barrier

    de Lange Ec;Danhof M;de Boer Ag;Breimer Dd

  • The role of population PK–PD modelling in paediatric clinical research

    Roosmarijn F. W. De Cock;Chiara Piana;Elke H. J. Krekels;Elke H. J. Krekels;Meindert Danhof

  • Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite α-hydroxymidazolam in healthy volunteers

    Jaap W Mandona;Bert Tuk;Alfred L van Steveninck;Douwe D Breimer

  • Markers of disease severity in chronic obstructive pulmonary disease.

    Luigi G. Franciosi;Clive P. Page;Bartolome R. Celli;Mario Cazzola

  • Extensions to the Visual Predictive Check to facilitate model performance evaluation

    Teun M. Post;Jan I. Freijer;Bart A. Ploeger;Meindert Danhof

  • Rate of increase in the plasma concentration of nifedipine as a major determinant of its hemodynamic effects in humans

    C H Kleinbloesem;C H Kleinbloesem;P Van Brummelen;P Van Brummelen;M Danhof;M Danhof;H Faber;H Faber

  • Variability in nifedipine pharmacokinetics and dynamics: A new oxidation polymorphism in man

    C.H. Kleinbloesem;P. van Brummelen;H. Faber;M. Danhof

  • Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling—A New Classification of Biomarkers

    Meindert Danhof;Gunnar Alvan;Svein G. Dahl;Jochen Kuhlmann

  • Electroencephalogram Effect Measures and Relationships Between Pharmacokinetics and Pharmacodynamics of Centrally Acting Drugs

    Jaap W. Mandema;Meindert Danhof

  • Clinical pharmacokinetics of pioglitazone

    D. A. Eckland;M. Danhof

  • Assay of antipyrine and its primary metabolites in plasma, saliva and urine by high-performance liquid chromatography and some preliminary results in man.

    M. Danhof;E. de Groot-van der Vis;D.D. Breimer

  • Explaining variability in tacrolimus pharmacokinetics to optimize early exposure in adult kidney transplant recipients.

    Rogier R Press;Bart A Ploeger;Jan den Hartigh;Tahar van der Straaten

  • Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs.

    J. B. M. M. Van Bree;A. G. De Boer;M. Danhof;L. A. Ginsel

  • A Mechanism-based Disease Progression Model for Comparison of Long-term Effects of Pioglitazone, Metformin and Gliclazide on Disease Processes Underlying Type 2 Diabetes Mellitus

    Willem de Winter;Joost DeJongh;Teun Post;Bart Ploeger

Frequent Co-Authors

Douwe D. Breimer
Douwe D. Breimer Leiden University
Dick Tibboel
Dick Tibboel Erasmus University Rotterdam
Adriaan P. IJzerman
Adriaan P. IJzerman Leiden University
Joke A. Bouwstra
Joke A. Bouwstra Leiden University
Albert Dahan
Albert Dahan Leiden University Medical Center
Lambertus A. Peletier
Lambertus A. Peletier Leiden University
Geny M. M. Groothuis
Geny M. M. Groothuis University of Groningen
Johan W. Mouton
Johan W. Mouton Radboud University Medical Center
Menno R. Kruk
Menno R. Kruk Leiden University
Amin Rostami-Hodjegan
Amin Rostami-Hodjegan University of Manchester

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