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Joke A. Bouwstra

Joke A. Bouwstra

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Chemistry
Netherlands
2025

D-Index & Metrics

Chemistry

D-Index
97
Citations
30239
World Ranking
1484
National Ranking
35

Research.com Recognitions

  • 2025 - Research.com Chemistry in Netherlands Leader Award
  • 2022 - Research.com Chemistry in Netherlands Leader Award

Overview

Joke A. Bouwstra is a researcher affiliated with Leiden University in the Netherlands, focusing on several areas within medicine and pharmaceutical sciences. Their research spans key fields such as Medicine, Pharmacology, Toxicology and Pharmaceutics, and Biochemistry, Genetics and Molecular Biology. Bouwstra's work prominently intersects with subfields including Pharmaceutical Science, Dermatology, Molecular Biology, Immunology, and Biomaterials.

The scientist has concentrated on main topics like Advancements in Transdermal Drug Delivery, Dermatology and Skin Diseases, Lipid Membrane Structure and Behavior, Allergic Rhinitis and Sensitization, Sphingolipid Metabolism and Signaling, Immunotherapy and Immune Responses, and Psoriasis: Treatment and Pathogenesis.

Recent publications by Joke A. Bouwstra reflect their ongoing research interests. Notable papers include:

  • The skin barrier: An extraordinary interface with an exceptional lipid organization, 2023, Progress in Lipid Research
  • Human skin equivalents: Impaired barrier function in relation to the lipid and protein properties of the stratum corneum, 2021, Advanced Drug Delivery Reviews

Other frequently cited papers in related research fields include works authored by different teams, such as "Glucocerebrosidase: Functions in and Beyond the Lysosome," 2020, Journal of Clinical Medicine, and "One Peptide for Them All: Gold Nanoparticles of Different Sizes Are Stabilized by a Common Peptide Amphiphile," 2020, ACS Nano.

Joke A. Bouwstra collaborates regularly with several researchers including Andreea Nădăban, Jannik Rousel, Gerrit S. Gooris, Robert Rißmann, and Martijn B. A. van Doorn, who have co-authored multiple publications together.

Research outputs by Bouwstra have been published frequently in venues such as Experimental Dermatology, Langmuir, Journal of Investigative Dermatology, Journal of Lipid Research, and European Journal of Pharmaceutical Sciences.

Best Publications

  • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers

    Claus-Michael Lehr;Joke A. Bouwstra;Etienne H. Schacht;Hans E. Junginger

  • Structure of the skin barrier and its modulation by vesicular formulations.

    Joke A Bouwstra;P Loan Honeywell-Nguyen;Gert S Gooris;Maria Ponec

  • The skin barrier in healthy and diseased state.

    Joke A. Bouwstra;Maria Ponec

  • Structural Investigations of Human Stratum Corneum by Small-Angle X-Ray Scattering

    Joke A Bouwstra;Joke A Bouwstra;Gert S Gooris;Gert S Gooris;Joop A van der Spek;Joop A van der Spek;Wim Bras;Wim Bras

  • The important role of stratum corneum lipids for the cutaneous barrier function

    J. van Smeden;M. Janssens;G.S. Gooris;J.A. Bouwstra

  • Vesicles as a tool for transdermal and dermal delivery

    P. Loan Honeywell-Nguyen;Joke A. Bouwstra

  • Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations

    T Marjukka Suhonen;Joke A. Bouwstra;Arto Urtti

  • Water distribution and related morphology in human stratum corneum at different hydration levels

    Joke A. Bouwstra;Anko de Graaff;Gert S. Gooris;Jaap Nijsse

  • Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients.

    Jeroen van Smeden;Joke A Bouwstra

  • The Formation of Competent Barrier Lipids in Reconstructed Human Epidermis Requires the Presence of Vitamin C

    Maria Ponec;Arij Weerheim;Johanna Kempenaar;Aat Mulder

  • Role of ceramide 1 in the molecular organization of the stratum corneum lipids

    J.A. Bouwstra;G.S. Gooris;F.E.R. Dubbelaar;A.M. Weerheim

  • Skin structure and mode of action of vesicles.

    J.A Bouwstra;P.L Honeywell-Nguyen

  • The lipid organisation in the skin barrier.

    J. A. Bouwstra;F. E. R. Dubbelaar;G. S. Gooris;M. Ponec

  • Structure of human stratum corneum as a function of temperature and hydration: A wide-angle X-ray diffraction study

    J.A. Bouwstra;G.S. Gooris;M.A.Salomons-de Vries;J.A. van der Spek

  • Aberrant lipid organization in stratum corneum of patients with atopic dermatitis and lamellar ichthyosis.

    Gonneke S.K. Pilgram;Debby C.J. Vissers;Hans van der Meulen;Henk K. Koerten

  • The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients.

    Jeroen van Smeden;Michelle Janssens;Edward C. J. Kaye;Peter J. Caspers

  • Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin.

    FJ Verbaan;SM Bal;DJ van den Berg;Whh Groenink

  • Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements.

    Benedicte A.I van den Bergh;Philip W Wertz;Hans E Junginger;Joke A Bouwstra

  • Phase behavior of isolated skin lipids

    J A Bouwstra;G S Gooris;K Cheng;A Weerheim

  • LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery

    Jeroen van Smeden;Louise Hoppel;Rob van der Heijden;Thomas Hankemeier

  • The skin barrier in healthy and diseased state

    J.A. Bouwstra;G.S. Gooris;D. Groen;M. Ponec

Frequent Co-Authors

Wim Jiskoot
Wim Jiskoot Leiden University
Maria Ponec
Maria Ponec Leiden University
Hans E. Junginger
Hans E. Junginger National University of Singapore
Gideon F.A. Kersten
Gideon F.A. Kersten Leiden University
Meindert Danhof
Meindert Danhof Leiden University
Wim E. Hennink
Wim E. Hennink Utrecht University
Cwj Cees Oomens
Cwj Cees Oomens Eindhoven University of Technology
Alexander Kros
Alexander Kros Leiden University
Wim Bras
Wim Bras Oak Ridge National Laboratory
Alain Hovnanian
Alain Hovnanian Imagine Institute for Genetic Diseases

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