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Biology and Biochemistry

D-Index
63
Citations
11623
World Ranking
10414
National Ranking
4520

Overview

Walter M. Holleran is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a focus on molecular biology as a significant subfield. Additional areas of study include microbiology and pulmonary and respiratory medicine.

The scientist's work explores various topics related to cellular and molecular mechanisms, including sphingolipid metabolism and signaling, antimicrobial peptides and activities, photodynamic therapy research studies, lipid membrane structure and behavior, and glycosylation and glycoproteins research.

Among the recent publications attributed to Holleran are:

  • Sphingosine-1-Phosphate-Cathelicidin Axis Plays a Pivotal Role in the Development of Cutaneous Squamous Cell Carcinoma (2024), Journal of Investigative Dermatology
  • Sphingolipid Activator Proteins Are Required for Epidermal Permeability Barrier Formation (2021), UNC Libraries

These works indicate an ongoing research interest in lipid signaling pathways and skin biology.

Collaborations have occurred with several researchers frequently coauthoring papers, including Kyungho Park, Kyong-Oh Shin, Young-Il Kim, Anna L. Nielsen-Scott, and C. Mainzer.

Publication venues associated with Holleran's work include the Journal of Investigative Dermatology and UNC Libraries, highlighting contributions both to peer-reviewed journals and academic repositories.

Best Publications

  • Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.

    W M Holleran;E I Ginns;G K Menon;J U Grundmann

  • Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function.

    Walter M. Holleran;I Yutaka Takagi;Gopinathan K. Menon;I Gunter Legler

  • Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing

    T Mauro;W M Holleran;S Grayson;W N Gao

  • Epidermal sphingolipids: Metabolism, function, and roles in skin disorders

    Walter M. Holleran;Walter M. Holleran;Yutaka Takagi;Yoshikazu Uchida

  • Barrier function regulates epidermal lipid and DNA synthesis

    E. Proksch;W.M. Holleran;G.K. Menon;P.M. Elias

  • A Homolog of Drosophila grainy head Is Essential for Epidermal Integrity in Mice

    Stephen B. Ting;Jacinta Caddy;Nikki Hislop;Tomasz Wilanowski

  • Infection and Inflammation Induce LDL Oxidation In Vivo

    Riaz A. Memon;Ilona Staprans;Mustafa Noor;Walter M. Holleran

  • Regulation of epidermal sphingolipid synthesis by permeability barrier function.

    WM Holleran;KR Feingold;MQ Man;WN Gao

  • Loss of functional ELOVL4 depletes very long-chain fatty acids (≥C28) and the unique ω-O-acylceramides in skin leading to neonatal death

    Vidyullatha Vasireddy;Yoshikazu Uchida;Norman Salem;Soo Yeon Kim

  • Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation.

    W M Holleran;M Q Man;W N Gao;G K Menon

  • Epidermal sphingomyelins are precursors for selected stratum corneum ceramides

    Yoshikazu Uchida;Mariko Hara;Hiroyuki Nishio;Ellen Sidransky

  • NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging.

    Martin J. Behne;Jamie W. Meyer;Kerry M. Hanson;Nicholas P. Barry

  • Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.

    Mao-Qiang Man;Yutaka Hatano;Seung H. Lee;Mona Man

  • Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism

    Peter M. Elias;Mary L. Williams;Walter M. Holleran;Yan J. Jiang

  • Low Molecular Weight Inhibitors in Corneal Ulcerationa

    Richard E. Galardy;Marie E. Cassabonne;Carlanne Giese;James H. Gilbert

  • UVB-Induced Alterations in Permeability Barrier Function: Roles for Epidermal Hyperproliferation and Thymocyte-Mediated Response

    Akinori Haratake;Yoshikazu Uchida;Yoshikazu Uchida;Matthias Schmuth;Matthias Schmuth;Osamu Tanno

  • Omega-Hydroxyceramides are Required for Corneocyte Lipid Envelope (CLE) Formation and Normal Epidermal Permeability Barrier Function

    Martin Behne;Yoshikazu Uchida;Taisuke Seki;Paul Ortiz de Montellano

  • Endotoxin and cytokines increase hepatic sphingolipid biosynthesis and produce lipoproteins enriched in ceramides and sphingomyelin

    Riaz A. Memon;Walter M. Holleran;Arthur H. Moser;Taisuke Seki

  • Omega-O-acylceramide, a lipid essential for mammalian survival.

    Yoshikazu Uchida;Walter M. Holleran

  • Permeability Barrier Disorder in Niemann–Pick Disease: Sphingomyelin–Ceramide Processing Required for Normal Barrier Homeostasis

    Matthias Schmuth;Mao-Qiang Man;Florian Weber;WenNi Gao

Frequent Co-Authors

Peter M. Elias
Peter M. Elias University of California, San Francisco
Yoshikazu Uchida
Yoshikazu Uchida University of California, San Francisco
Kenneth R. Feingold
Kenneth R. Feingold University of California, San Francisco
Theodora M. Mauro
Theodora M. Mauro University of California, San Francisco
Debra Crumrine
Debra Crumrine University of California, San Francisco
Gopinathan K. Menon
Gopinathan K. Menon California Academy of Sciences
Matthias Schmuth
Matthias Schmuth Innsbruck Medical University
Carl Grunfeld
Carl Grunfeld University of California, San Francisco
Ellen Sidransky
Ellen Sidransky National Institutes of Health
Edward I. Ginns
Edward I. Ginns University of Massachusetts Chan Medical School

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