World's Best Scientists 2026 revealed!

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Genetics

D-Index
57
Citations
10815
World Ranking
3424
National Ranking
1482

Overview

Edward I. Ginns is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research work spans multiple fields, primarily focused on Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, they have contributed to subfields including Physiology, Public Health, Environmental and Occupational Health, Genetics, Pediatrics, Perinatology and Child Health, and Cell Biology.

The scientist's research topics encompass several specialized areas. These include Genetic and Kidney Cyst Diseases, Lysosomal Storage Disorders Research, Mosquito-borne diseases and control, Fetal and Pediatric Neurological Disorders, Microtubule and mitosis dynamics, Autophagy in Disease and Therapy, and Calcium signaling and nucleotide metabolism.

Edward I. Ginns has published in several academic venues, with a notable concentration in the journal Molecular Genetics and Metabolism. Their frequent publication venues are as follows:

  • Molecular Genetics and Metabolism
  • The American Journal of Human Genetics
  • Scientific Reports

Their recent works include four articles published between 2020 and 2021, reflecting their active engagement in current biomedical research. These papers are:

  • "Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy," 2020, The American Journal of Human Genetics
  • "Gaucher disease and SARS-CoV-2 infection: Emerging management challenges," 2020, Molecular Genetics and Metabolism
  • "Gaucher disease in the COVID-19 pandemic environment: The good, the bad and the unknown," 2021, Molecular Genetics and Metabolism
  • "Multi-omic analyses in Abyssinian cats with primary renal amyloid deposits," 2021, Scientific Reports
  • "COVID-19 patient impact: A survey of the Gaucher community involving patients, caregivers and family members based in the US to determine impact of the pandemic," 2021, Molecular Genetics and Metabolism

Throughout their work, Edward I. Ginns has collaborated with several researchers repeatedly. Their frequent coauthors include:

  • Ellen Sidransky
  • Leslie A. Lyons
  • Reuben M. Buckley
  • Paulo C. Alves
  • Gregory S. Barsh

Best Publications

  • Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the old order amish

    John R. Kelsoe;Edward I. Ginns;Janice A. Egeland;Daniela S. Gerhard

  • Vasopressin V1b receptor knockout reduces aggressive behavior in male mice.

    S. R. Wersinger;Edward I. Ginns;A-M O'Carroll;S. J. Lolait

  • Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis.

    Themis R. Kyriakides;Yu Hong Zhu;Lynne T. Smith;Steven D. Bain

  • A mutation in the human glucocerebrosidase gene in neuronopathic Gaucher's disease.

    Shoji Tsuji;Prabhakara V. Choudary;Brian M. Martin;Barbara K. Stubblefield

  • Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.

    W M Holleran;E I Ginns;G K Menon;J U Grundmann

  • Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition.

    W. Scott Young;Emily Shepard;Janet Amico;Lothar Hennighausen

  • Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene.

    V. L. J. Tybulewicz;V. L. J. Tybulewicz;M. L. Tremblay;M. L. Tremblay;LaMarca;R. Willemsen

  • Molecular Determinants of Dysregulated GABAergic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia

    Nikolaos Mellios;Hsien-Sung Huang;Stephen P. Baker;Marzena Galdzicka

  • Lack of an association between a dopamine-4 receptor polymorphism and attention-deficit/hyperactivity disorder: genetic and brain morphometric analyses.

    F X Castellanos;E Lau;N Tayebi;P Lee

  • Glucosylsphingosine accumulation in tissues from patients with Gaucher disease: correlation with phenotype and genotype.

    Eduard Orvisky;Joseph K Park;Mary E LaMarca;Edward I Ginns

  • Genetic heterogeneity in type 1 Gaucher disease: multiple genotypes in Ashkenazic and non-Ashkenazic individuals.

    Shoji Tsuji;Brian M. Martin;John A. Barranger;Barbara K. Stubblefield

  • Prolonged ethanol inhalation decreases gamma-aminobutyric acidA receptor alpha subunit mRNAs in the rat cerebral cortex.

    P Montpied;A L Morrow;J W Karanian;E I Ginns

  • Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs.

    Karen L. O'Malley;Michael J. Anhalt;Brian M. Martin;John R. Kelsoe

  • CD4 receptor binding peptides that block HIV infectivity cause human monocyte chemotaxis. Relationship to vasoactive intestinal polypeptide.

    Michael R. Ruff;Brian M. Martin;Edward I. Ginns;William L. Farrar

  • A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish.

    Edward I. Ginns;Jurg Ott;Janice A. Egeland;Cleona R. Allen

  • Gaucher disease in the neonate: a distinct Gaucher phenotype is analogous to a mouse model created by targeted disruption of the glucocerebrosidase gene.

    Ellen Sidransky;David M Sherer;Edward I Ginns

  • A canine chromosome 7 locus confers compulsive disorder susceptibility.

    N. H. Dodman;E. K. Karlsson;E. K. Karlsson;A. Moon-Fanelli;M. Galdzicka

  • Bone-marrow transplantation in severe Gaucher's disease.

    Joel M. Rappeport;Edward I. Ginns

  • Identification of Three Additional Genes Contiguous to the Glucocerebrosidase Locus on Chromosome 1q21: Implications for Gaucher Disease

    Suzanne L. Winfield;Nahid Tayebi;Brian M. Martin;Edward I. Ginns

  • Isolation, Characterization, and Proteolysis of Human Prosaposin, the Precursor of Saposins (Sphingolipid Activator Proteins)

    M. Hiraiwa;J.S. Obrien;Y. Kishimoto;M. Galdzicka

Frequent Co-Authors

Ellen Sidransky
Ellen Sidransky National Institutes of Health
Brian M. Martin
Brian M. Martin National Institutes of Health
John A. Barranger
John A. Barranger University of Pittsburgh
Judith L. Rapoport
Judith L. Rapoport National Institutes of Health
J. M. Tager
J. M. Tager University of Amsterdam
Roscoe O. Brady
Roscoe O. Brady Beth Israel Deaconess Medical Center
Arnold J. J. Reuser
Arnold J. J. Reuser Erasmus University Rotterdam
Shoji Tsuji
Shoji Tsuji University of Tokyo
Walter M. Holleran
Walter M. Holleran University of California, San Francisco
Rob Willemsen
Rob Willemsen Erasmus University Rotterdam

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