What is he best known for?
The fields of study he is best known for:
John A. Barranger focuses on Molecular biology, Glucocerebrosidase, Biochemistry, Pathology and Gene.
John A. Barranger has researched Molecular biology in several fields, including Mutation, Glucosylceramidase, Complementary DNA, Viral vector and Fibroblast.
While the research belongs to areas of Viral vector, John A. Barranger spends his time largely on the problem of Bone marrow, intersecting his research to questions surrounding Genetic enhancement, Virology, Haematopoiesis and Transplantation.
His research in Glucocerebrosidase intersects with topics in Hepatosplenomegaly, Allele and Neuraminidase.
In general Biochemistry, his work in Glucocerebroside, Intracellular and Extracellular is often linked to Lymphocyte activating factor and Latex beads linking many areas of study.
In his study, which falls under the umbrella issue of Pathology, Hyperdiploidy and Cytokine genes is strongly linked to Immunology.
His most cited work include:
- Fabry disease, an under-recognized multisystemic disorder: expert recommendations for diagnosis, management, and enzyme replacement therapy. (570 citations)
- A mutation in the human glucocerebrosidase gene in neuronopathic Gaucher's disease. (266 citations)
- Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. (234 citations)
What are the main themes of his work throughout his whole career to date?
John A. Barranger mainly investigates Glucocerebrosidase, Biochemistry, Molecular biology, Enzyme and Disease.
His Glucocerebrosidase research is multidisciplinary, incorporating perspectives in Phenotype, Fibroblast and Gaucher's disease.
The Molecular biology study combines topics in areas such as Cell culture, Complementary DNA, Genetic enhancement and Antibody, Monoclonal antibody.
He studied Enzyme and Chromatography that intersect with Gel electrophoresis.
John A. Barranger has included themes like Clinical trial and Bioinformatics in his Disease study.
His work carried out in the field of Enzyme replacement therapy brings together such families of science as Endocrinology and Pediatrics.
He most often published in these fields:
- Glucocerebrosidase (35.39%)
- Biochemistry (33.15%)
- Molecular biology (29.78%)
What were the highlights of his more recent work (between 2001-2014)?
- Disease (17.98%)
- Enzyme replacement therapy (8.99%)
- Fabry disease (4.49%)
In recent papers he was focusing on the following fields of study:
His main research concerns Disease, Enzyme replacement therapy, Fabry disease, Pediatrics and Genetic enhancement.
His work deals with themes such as Psychotherapist, Clinical trial, Immunology and Intensive care medicine, which intersect with Disease.
His studies deal with areas such as Gastroenterology and Endocrinology as well as Enzyme replacement therapy.
His study in Pediatrics is interdisciplinary in nature, drawing from both Metachromatic leukodystrophy, Surgery, Vascular disease and Type 1 Gaucher Disease.
Within one scientific family, he focuses on topics pertaining to Transduction under Genetic enhancement, and may sometimes address concerns connected to Molecular biology, Cancer research, Cd34 cells, Clonogenic assay and CD34.
His Glucocerebrosidase study results in a more complete grasp of Biochemistry.
Between 2001 and 2014, his most popular works were:
- Fabry disease, an under-recognized multisystemic disorder: expert recommendations for diagnosis, management, and enzyme replacement therapy. (570 citations)
- Improvement of bone disease by imiglucerase (Cerezyme) therapy in patients with skeletal manifestations of type 1 Gaucher disease: results of a 48-month longitudinal cohort study. (95 citations)
- Imiglucerase (Cerezyme) improves quality of life in patients with skeletal manifestations of Gaucher disease. (81 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Internal medicine
His primary areas of investigation include Enzyme replacement therapy, Imiglucerase, Disease, Internal medicine and Genetic enhancement.
He has researched Enzyme replacement therapy in several fields, including Surgery and Pediatrics.
In the subject of general Disease, his work in Fabry disease is often linked to Correlation, thereby combining diverse domains of study.
His research integrates issues of Gastroenterology and Endocrinology in his study of Internal medicine.
His Genetic enhancement research also works with subjects such as
- Neuropathology, which have a strong connection to Substrate reduction therapy,
- Glucocerebrosidase most often made with reference to Kupffer cell.
His Glucocerebrosidase research integrates issues from Adenoviridae, Viral vector and Gaucher's disease.
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