World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
27380
World Ranking
3656
National Ranking
1821

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ellen Sidransky is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology with significant contributions in physiology, cell biology, molecular biology, neurology, and organic chemistry.

The scientist's work extensively covers topics related to lysosomal storage disorders research, cellular transport and secretion, and Parkinson's disease mechanisms and treatments. Other areas of focus include carbohydrate chemistry and synthesis, CRISPR and genetic engineering, autophagy in disease and therapy, and genomics and rare diseases.

Frequent coauthors in their publications include:

  • Grisel Lopez
  • Nahid Tayebi
  • Emory Ryan
  • Yu Chen
  • Ellen Hertz

Publications have appeared most frequently in venues such as:

  • Molecular Genetics and Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Movement Disorders
  • American Journal of Medical Genetics Part A
  • Neurology

Recent papers authored or co-authored by Ellen Sidransky include:

  • Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture, 2021, Nature Genetics
  • Lysosomal dysfunction in neurodegeneration: emerging concepts and methods, 2022, Trends in Neurosciences
  • The definition of neuronopathic Gaucher disease, 2020, Journal of Inherited Metabolic Disease
  • Diagnosing neuronopathic Gaucher disease: New considerations and challenges in assigning Gaucher phenotypes, 2021, Molecular Genetics and Metabolism
  • The natural history of type 2 Gaucher disease in the 21st century, 2020, Neurology

Sidransky has been recognized as a member of the Association of American Physicians. Their scientific contributions are characterized by a focus on lysosomal and neurological disorders, as well as the genetic and cellular mechanisms underlying these diseases.

Best Publications

  • Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

    Ellen Sidransky;Michael A. Nalls;Jan O. Aasly;Judith Aharon-Peretz

  • Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

    Joseph R. Mazzulli;You Hai Xu;You Hai Xu;Ying Sun;Ying Sun;Adam L. Knight

  • Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA).

    Kathleen S. Hruska;Mary E. LaMarca;C. Ronald Scott;Ellen Sidransky

  • The link between the GBA gene and parkinsonism

    Ellen Sidransky;Grisel Lopez

  • Gaucher disease: complexity in a “simple” disorder

    Ellen Sidransky

  • A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies

    Michael A. Nalls;Raquel Duran;Grisel Lopez;Marzena Kurzawa-Akanbi

  • Neuropathology provides clues to the pathophysiology of Gaucher disease

    Kondi Wong;Ellen Sidransky;Ajay Verma;Tonghui Mixon

  • Glucocerebrosidase mutations in subjects with parkinsonism

    Alicia Lwin;Eduard Orvisky;Ozlem Goker-Alpan;Mary E LaMarca

  • Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.

    Karen E Murphy;Karen E Murphy;Amanda M Gysbers;Sarah K Abbott;Sarah K Abbott;Nahid Tayebi

  • Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

    Ruth Chia;Marya S. Sabir;Sara Bandres-Ciga

  • Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy.

    Suzanne Lesage;Valérie Drouet;Elisa Majounie;Vincent Deramecourt

  • Parkinsonism among Gaucher disease carriers.

    O Goker-Alpan;R Schiffmann;M E LaMarca;R L Nussbaum

  • Analysis and classification of 304 mutant alleles in patients with type 1 and type 3 Gaucher disease.

    Vuk Koprivica;Deborah L Stone;Joseph K. Park;Megan Callahan

  • Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

    A. Beilina;I. N. Rudenko;A. Kaganovich;L. Civiero

  • Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.

    W M Holleran;E I Ginns;G K Menon;J U Grundmann

  • Gaucher disease with parkinsonian manifestations: does glucocerebrosidase deficiency contribute to a vulnerability to parkinsonism?

    N. Tayebi;Jamie M Walker;B. Stubblefield;E. Orvisky

  • Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene.

    V. L. J. Tybulewicz;V. L. J. Tybulewicz;M. L. Tremblay;M. L. Tremblay;LaMarca;R. Willemsen

  • Glucocerebrosidase mutations are an important risk factor for Lewy body disorders

    O. Goker-Alpan;B. I. Giasson;M. J. Eblan;J. Nguyen

  • Glucocerebrosidase gene mutations in patients with type 2 Gaucher disease.

    Deborah L. Stone;Nahid Tayebi;Eduard Orvisky;Barbara Stubblefield

  • Glucocerebrosidase Gene Mutations: A Risk Factor for Lewy Body Disorders

    Ignacio F. Mata;Ali Samii;Seth H. Schneer;John W. Roberts

Frequent Co-Authors

Edward I. Ginns
Edward I. Ginns University of Massachusetts Chan Medical School
Christopher P. Austin
Christopher P. Austin National Institutes of Health
Wei Zheng
Wei Zheng National Institutes of Health
Brian M. Martin
Brian M. Martin National Institutes of Health
Raphael Schiffmann
Raphael Schiffmann Baylor University
Judith L. Rapoport
Judith L. Rapoport National Institutes of Health
Andrew B. Singleton
Andrew B. Singleton National Institutes of Health
Jose Bras
Jose Bras Van Andel Institute
Alexis Brice
Alexis Brice Institut du Cerveau
Dena G. Hernandez
Dena G. Hernandez National Institutes of Health

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