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Genetics
Canada
2026
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Genetics and Molecular Biology
Canada
2024

D-Index & Metrics

Genetics

D-Index
162
Citations
104164
World Ranking
92
National Ranking
3

Medicine

D-Index
164
Citations
106884
World Ranking
658
National Ranking
20

Research.com Recognitions

  • 2026 - Research.com Genetics in Canada Leader Award
  • 2025 - Research.com Genetics in Canada Leader Award
  • 2024 - Research.com Genetics in Canada Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Canada Leader Award
  • 2023 - Research.com Genetics in Canada Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Canada Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Canada Leader Award
  • 2016 - Fellow of the Royal Society of Canada Academy of Science

Overview

Guy A. Rouleau is affiliated with the Montreal Neurological Institute and Hospital in Canada. Their research spans multiple fields, primarily within medicine and biochemistry, genetics, and molecular biology. The focus of their work includes genetics, neurology, molecular biology, cellular and molecular neuroscience, and psychiatry and mental health.

The scientist's main topics of study touch on several areas:

  • Genetics and Neurodevelopmental Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Neurogenetic and Muscular Disorders Research
  • Neurological diseases and metabolism
  • Amyotrophic Lateral Sclerosis Research
  • Bipolar Disorder and Treatment
  • Hereditary Neurological Disorders

Guy A. Rouleau has contributed to numerous research papers, including recent notable publications such as:

  • Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors, 2020, Nature Genetics
  • Evolution of immune genes is associated with the Black Death, 2022, Nature
  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome, 2021, Nature Communications
  • Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets, 2021, JAMA Neurology
  • Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic, 2022, The Journal of Experimental Medicine

The scientist frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Journal of the Neurological Sciences
  • Movement Disorders
  • Neurology

Guy A. Rouleau collaborates regularly with a number of co-authors, including:

  • Patrick A. Dion
  • Ziv Gan-Or
  • Dan Spiegelman
  • Jay P. Ross
  • Mehrdad A. Estiar

Recognition of their work includes being named a Fellow of the Royal Society of Canada in 2016 by the Academy of Science.

Best Publications

  • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

    T. J. Kwiatkowski;D. A. Bosco;D. A. Bosco;A. L. LeClerc;A. L. LeClerc;E. Tamrazian

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

    Olivier Delattre;Jessica Zucman;Béatrice Plougastel;Chantal Desmaze

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

    Edor Kabashi;Paul N Valdmanis;Patrick Dion;Dan Spiegelman

  • Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

    Guy A. Rouleau;Philippe Merel;Mohini Lutchman;Marc Sanson;Marc Sanson

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2

    Stefan M. Pulst;Alex Nechiporuk;Alex Nechiporuk;Tamilla Nechiporuk;Tamilla Nechiporuk;Suzana Gispert

  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

    Elizabeth T. Cirulli;Brittany N Lasseigne;Slave Petrovski;Peter C Sapp

  • Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy

    Brais B;Bouchard Jp;Xie Yg;Rochefort Dl

  • A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

    Shinji Hadano;Collette K. Hand;Hitoshi Osuga;Yoshiko Yanagisawa

  • Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy

    Patrick Cossette;Lidong Liu;Katéri Brisebois;Haiheng Dong;Haiheng Dong

  • Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

    Juliane Winkelmann;Barbara Schormair;Peter Lichtner;Stephan Ripke

  • A genome-wide linkage and association scan reveals novel loci for autism

    Lauren A. Weiss;Lauren A. Weiss;Dan E. Arking;Mark J. Daly;Mark J. Daly;Aravinda Chakravarti

  • Risk Factors for Suicide Completion in Major Depression: A Case-Control Study of Impulsive and Aggressive Behaviors in Men

    Alexandre Dumais;A. D. Lesage;Martin Alda;Guy Rouleau

  • Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

    B. R. Seizinger;G. A. Rouleau;L. J. Ozelius;A. H. Lane

  • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

    Colm O'Dushlaine;Lizzy Rossin;Phil H. Lee;Laramie Duncan;Laramie Duncan

Frequent Co-Authors

Patrick A. Dion
Patrick A. Dion Montreal Neurological Institute and Hospital
Ziv Gan-Or
Ziv Gan-Or McGill University
Gustavo Turecki
Gustavo Turecki Douglas Mental Health University Institute
Martin Alda
Martin Alda Dalhousie University
Ridha Joober
Ridha Joober Douglas Mental Health University Institute
Bernard Brais
Bernard Brais Montreal Neurological Institute and Hospital
Fadi F. Hamdan
Fadi F. Hamdan University of Montreal
Jacques L. Michaud
Jacques L. Michaud University of Montreal
Sven Cichon
Sven Cichon University of Basel
Jacques Montplaisir
Jacques Montplaisir University of Montreal

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