D-Index & Metrics Best Publications
Joachim Grötzinger

Joachim Grötzinger

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 67 Citations 13,210 210 World Ranking 3671 National Ranking 281

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Joachim Grötzinger mainly investigates Cell biology, Glycoprotein 130, Molecular biology, Signal transduction and Biochemistry. His biological study spans a wide range of topics, including Interleukin-17 receptor, Leukemia inhibitory factor receptor, Ligand, Receptor complex and Ciliary neurotrophic factor. His Glycoprotein 130 study combines topics from a wide range of disciplines, such as Common gamma chain, Protein subunit, Receptor, Interleukin-3 receptor and Interleukin-6 receptor.

His Molecular biology research is multidisciplinary, incorporating elements of Polymerase, Carcinogenesis, Alpha chain, STAT3 and Interleukin 10. He works mostly in the field of Signal transduction, limiting it down to topics relating to Interleukin 6 and, in certain cases, In vivo. His work in the fields of Biochemistry, such as Peptide sequence, Binding protein and Escherichia coli, overlaps with other areas such as Mycobacterium bovis.

His most cited work include:

  • A bioactive designer cytokine for human hematopoietic progenitor cell expansion (470 citations)
  • Structural basis of calcification inhibition by α2-HS glycoprotein/fetuin-A - Formation of colloidal calciprotein particles (367 citations)
  • The IL-6/sIL-6R complex as a novel target for therapeutic approaches. (285 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Glycoprotein 130, Cell biology, Molecular biology and Receptor are his primary areas of study. His Glycoprotein 130 study integrates concerns from other disciplines, such as Interleukin-6 receptor, Cytokine receptor and Fusion protein. In his study, Transmembrane protein is inextricably linked to Disintegrin, which falls within the broad field of Cell biology.

His study in Molecular biology is interdisciplinary in nature, drawing from both Antibody, Monoclonal antibody and Receptor complex. His Receptor research incorporates themes from Epitope, Stereochemistry and Cytokine. His work deals with themes such as Interleukin and Protein subunit, which intersect with Signal transduction.

He most often published in these fields:

  • Biochemistry (28.30%)
  • Glycoprotein 130 (27.55%)
  • Cell biology (23.40%)

What were the highlights of his more recent work (between 2013-2020)?

  • Cell biology (23.40%)
  • Molecular biology (23.40%)
  • Disintegrin (5.28%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Molecular biology, Disintegrin, Biochemistry and Metalloproteinase. His research in Cell biology is mostly concerned with Signal transduction. His studies in Molecular biology integrate themes in fields like Myocyte, Histone acetyltransferase, Interleukin-6 receptor and Receptor complex.

The Biochemistry study combines topics in areas such as Aptamer and Interleukin-6 receptor binding. Joachim Grötzinger interconnects Glycoprotein 130, Phosphorylation and Stereochemistry in the investigation of issues within Receptor. His Glycoprotein 130 research is within the category of Interleukin 6.

Between 2013 and 2020, his most popular works were:

  • Phosphatidylserine exposure is required for ADAM17 sheddase function (82 citations)
  • Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation. (50 citations)
  • Proteolytic Cleavage Governs Interleukin-11 Trans-signaling (50 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His main research concerns Cell biology, ADAM17 Protein, Sheddase, Metalloproteinase and Disintegrin. His research integrates issues of Serine, Proteases, Cell membrane, Interleukin-6 receptor and Signal transduction in his study of ADAM17 Protein. His studies deal with areas such as Cleavage, Immunology, Neutrophil elastase, Fusion protein and Interleukin as well as Signal transduction.

His Disintegrin study is concerned with the larger field of Biochemistry. His research in Biochemistry intersects with topics in Aptamer and Interleukin-6 receptor binding. His research in Downregulation and upregulation focuses on subjects like Cell, which are connected to Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structural basis of calcification inhibition by α2-HS glycoprotein/fetuin-A - Formation of colloidal calciprotein particles

Alexander Heiss;Alexander DuChesne;Bernd Denecke;Joachim Grötzinger.
Journal of Biological Chemistry (2003)

557 Citations

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

Martina Fischer;Jutta Goldschmitt;Christian Peschel;Just P. G. Brakenhoff.
Nature Biotechnology (1997)

499 Citations

The IL-6/sIL-6R complex as a novel target for therapeutic approaches.

Stefan Rose-John;Georg H Waetzig;Jürgen Scheller;Joachim Grötzinger.
Expert Opinion on Therapeutic Targets (2007)

434 Citations

Differential Activation of Acute Phase Response Factor/Stat3 and Stat1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 II. Src HOMOLOGY SH2 DOMAINS DEFINE THE SPECIFICITY OF STAT FACTOR ACTIVATION

Ulrike Hemmann;Claudia Gerhartz;Birgit Heesel;Jürgen Sasse.
Journal of Biological Chemistry (1996)

389 Citations

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

Erwan Mortier;Erwan Mortier;Agnès Quéméner;Agnès Quéméner;Patricia Vusio;Inken Lorenzen.
Journal of Biological Chemistry (2006)

350 Citations

Plasticity and cross-talk of interleukin 6-type cytokines.

Christoph Garbers;Heike M. Hermanns;Fred Schaper;Gerhard Müller-Newen.
Cytokine & Growth Factor Reviews (2012)

283 Citations

Molecular Determinants of KCNQ (Kv7) K+ Channel Sensitivity to the Anticonvulsant Retigabine

Anne Schenzer;Thomas Friedrich;Michael Pusch;Paul Saftig.
The Journal of Neuroscience (2005)

269 Citations

Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.

Thomas C.G. Bosch;René Augustin;Friederike Anton-Erxleben;Sebastian Fraune.
Developmental and Comparative Immunology (2009)

226 Citations

The Nucleotide-Binding Oligomerization Domain-Like Receptor NLRC5 Is Involved in IFN-Dependent Antiviral Immune Responses

Sven Kuenzel;Andreas Till;Michael Winkler;Robert Häsler.
Journal of Immunology (2010)

220 Citations

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

Sunke Himpel;Pascal Panzer;Klaus Eirmbter;Hanna Czajkowska.
Biochemical Journal (2001)

193 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Joachim Grötzinger

Stefan Rose-John

Stefan Rose-John

Kiel University

Publications: 281

Jürgen Scheller

Jürgen Scheller

Heinrich Heine University Düsseldorf

Publications: 84

Martina Pohl

Martina Pohl

Forschungszentrum Jülich

Publications: 61

Peter C. Heinrich

Peter C. Heinrich

University of Freiburg

Publications: 60

Thomas C. G. Bosch

Thomas C. G. Bosch

Kiel University

Publications: 39

Fred Schaper

Fred Schaper

Otto-von-Guericke University Magdeburg

Publications: 36

Gerhard Müller-Newen

Gerhard Müller-Newen

RWTH Aachen University

Publications: 35

Iris Behrmann

Iris Behrmann

University of Luxembourg

Publications: 33

Bernhard Lüscher

Bernhard Lüscher

RWTH Aachen University

Publications: 31

Simon Arnett Jones

Simon Arnett Jones

Cardiff University

Publications: 29

Matthias Leippe

Matthias Leippe

Kiel University

Publications: 24

Michael Müller

Michael Müller

Forschungszentrum Jülich

Publications: 24

Jean-François Gauchat

Jean-François Gauchat

University of Geneva

Publications: 19

Matthias Ernst

Matthias Ernst

La Trobe University

Publications: 19

Makoto Kuro-o

Makoto Kuro-o

Jichi Medical University

Publications: 17

Jörg Köhl

Jörg Köhl

University of Lübeck

Publications: 17

Something went wrong. Please try again later.