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Joachim Grötzinger

Joachim Grötzinger

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
16578
World Ranking
4891
National Ranking
364

Overview

Joachim Grötzinger is currently affiliated with Kiel University in Germany. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with specific work in Immunology, Oncology, Radiology, Nuclear Medicine and Imaging, Pathology and Forensic Medicine, and Microbiology.

The scientist's research addresses several main topics, including:

  • Cytokine Signaling Pathways and Interactions
  • Immune Response and Inflammation
  • Monoclonal and Polyclonal Antibodies Research
  • Psoriasis: Treatment and Pathogenesis
  • Immune Cell Function and Interaction
  • Antimicrobial Peptides and Activities
  • Polydiacetylene-based materials and applications

Grötzinger has published in numerous scientific journals, with frequent appearances in the following venues:

  • Journal of Biological Chemistry
  • PLoS ONE
  • Biochimica et Biophysica Acta (BBA) - Biomembranes
  • iScience
  • European Journal of Human Genetics

Among recent publications are:

  • "Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells," 2020, PLoS ONE
  • "Influence of disulfide bonds in human beta defensin-3 on its strain specific activity against Gram-negative bacteria," 2020, Biochimica et Biophysica Acta (BBA) - Biomembranes
  • "A single aromatic residue in sgp130Fc/olamkicept allows the discrimination between interleukin-6 and interleukin-11 trans-signaling," 2021, iScience
  • "Deciphering site 3 interactions of interleukin 12 and interleukin 23 with their cognate murine and human receptors," 2020, Journal of Biological Chemistry
  • "Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction," 2021, Journal of Biological Chemistry

Grötzinger has collaborated with several frequent co-authors, including:

  • Christoph Garbers
  • Juliane Lokau
  • Yvonne Garbers
  • Alessandra Esch
  • Jens M. Moll

Best Publications

  • Structural basis of calcification inhibition by α2-HS glycoprotein/fetuin-A - Formation of colloidal calciprotein particles

    Alexander Heiss;Alexander DuChesne;Bernd Denecke;Joachim Grötzinger

  • A bioactive designer cytokine for human hematopoietic progenitor cell expansion

    Martina Fischer;Jutta Goldschmitt;Christian Peschel;Just P. G. Brakenhoff

  • The IL-6/sIL-6R complex as a novel target for therapeutic approaches.

    Stefan Rose-John;Georg H Waetzig;Jürgen Scheller;Joachim Grötzinger

  • Plasticity and cross-talk of interleukin 6-type cytokines.

    Christoph Garbers;Heike M. Hermanns;Fred Schaper;Gerhard Müller-Newen

  • Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

    Erwan Mortier;Agnès Quéméner;Agnès Quéméner;Patricia Vusio;Inken Lorenzen

  • Differential Activation of Acute Phase Response Factor/Stat3 and Stat1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130 II. Src HOMOLOGY SH2 DOMAINS DEFINE THE SPECIFICITY OF STAT FACTOR ACTIVATION

    Ulrike Hemmann;Claudia Gerhartz;Birgit Heesel;Jürgen Sasse

  • Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine.

    Anne Schenzer;Thomas Friedrich;Michael Pusch;Paul Saftig

  • Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.

    Thomas C.G. Bosch;René Augustin;Friederike Anton-Erxleben;Sebastian Fraune

  • The Nucleotide-Binding Oligomerization Domain-Like Receptor NLRC5 Is Involved in IFN-Dependent Antiviral Immune Responses

    Sven Kuenzel;Andreas Till;Michael Winkler;Robert Häsler

  • A role for IL-27p28 as an antagonist of gp130-mediated signaling

    Jason S. Stumhofer;Elia D. Tait;William J. Quinn Iii;Nancy Hosken

  • Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

    Sunke Himpel;Pascal Panzer;Klaus Eirmbter;Hanna Czajkowska

  • PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation

    Mei Yu;Sabine Schreek;Christa Cerni;Chantal Schamberger

  • Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2‐Hydroxy Ketones

    Hans Iding;Thomas Dünnwald;Lasse Greiner;Andreas Liese

  • Signaling of Human Ciliary Neurotrophic Factor (CNTF) Revisited THE INTERLEUKIN-6 RECEPTOR CAN SERVE AS AN α-RECEPTOR FOR CNTF

    Björn Schuster;Marina Kovaleva;Yi Sun;Petra Regenhard

  • Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice

    Martin Roderfeld;Ralf Weiskirchen;Sandra Wagner;Marie-Luise Berres

  • The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes

    Joachim Grotzinger;Günther Kurapkat;Axel Wollmer;Michael Kalai

  • Inhibition of Classic Signaling Is a Novel Function of Soluble Glycoprotein 130 (sgp130), Which Is Controlled by the Ratio of Interleukin 6 and Soluble Interleukin 6 Receptor

    Christoph Garbers;Wolfgang Thaiss;Gareth W. Jones;Georg H. Waetzig

  • Phosphatidylserine exposure is required for ADAM17 sheddase function

    Anselm Sommer;Felix Kordowski;Joscha Büch;Thorsten Maretzky

  • Refinement of the Binding Site and Mode of Action of the Anticonvulsant Retigabine on KCNQ K+ Channels

    Wienke Lange;Jan Geissendörfer;Anne Schenzer;Joachim Grötzinger

  • T Cell Recognition of Desmoglein 3 Peptides in Patients with Pemphigus Vulgaris and Healthy Individuals

    Christian M. Veldman;Kerstin L. Gebhard;Wolfgang Uter;Ralf Wassmuth

Frequent Co-Authors

Stefan Rose-John
Stefan Rose-John Kiel University
Jürgen Scheller
Jürgen Scheller Heinrich Heine University Düsseldorf
Matthias Leippe
Matthias Leippe Kiel University
Peter C. Heinrich
Peter C. Heinrich University of Freiburg
Gerhard Müller-Newen
Gerhard Müller-Newen RWTH Aachen University
Yannick Jacques
Yannick Jacques University of Nantes
Frank D. Sönnichsen
Frank D. Sönnichsen Kiel University
Martina Pohl
Martina Pohl Forschungszentrum Jülich
Wiebke Arlt
Wiebke Arlt University of Birmingham
Georg Thaller
Georg Thaller Kiel University

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