World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
77
Citations
25282
World Ranking
1336
National Ranking
91

Overview

Jürgen Scheller is affiliated with Heinrich Heine University Düsseldorf in Germany. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a substantial focus on immunology, oncology, epidemiology, molecular biology, and physiology.

The scientist's work extensively covers several main research topics including:

  • Cytokine Signaling Pathways and Interactions
  • Immune Cell Function and Interaction
  • Monoclonal and Polyclonal Antibodies Research
  • Toxin Mechanisms and Immunotoxins
  • CAR-T cell therapy research
  • Interferon and Immune Responses
  • Sirtuins and Resveratrol in Medicine

Jürgen Scheller has published research in various scientific venues, frequently contributing to the Journal of Biological Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Cells, Communications Biology, and FEBS Journal.

Frequent coauthors with whom Scheller has collaborated include:

  • Doreen M. Floß
  • Jens M. Moll
  • Julia Ettich
  • Kristina Behnke
  • Puyan Rafii

Recent publications by Jürgen Scheller illustrate their focus on immunological pathways, inflammation, and cytokine signaling. Notable papers include:

  • "Targeting IL-6 trans-signalling: past, present and future prospects" (2023), published in Nature Reviews. Immunology
  • "Lactate and IL6 define separable paths of inflammatory metabolic adaptation" (2021), published in Science Advances
  • "IL-12 and IL-23-Close Relatives with Structural Homologies but Distinct Immunological Functions" (2020), published in Cells
  • "IL-6 in the infarcted heart is preferentially formed by fibroblasts and modulated by purinergic signaling" (2023), published in Journal of Clinical Investigation
  • "Exclusive inhibition of IL-6 trans-signaling by soluble gp130FlyRFc" (2021), published in Cytokine X

Best Publications

  • The pro- and anti-inflammatory properties of the cytokine interleukin-6

    Jürgen Scheller;Athena Chalaris;Dirk Schmidt-Arras;Stefan Rose-John

  • IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

    Sergei Grivennikov;Eliad Karin;Janos Terzic;Janos Terzic;Daniel Mucida

  • Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.

    Stefan Rose‐John;Jürgen Scheller;Greg Elson;Simon A. Jones

  • Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

    Simon Arnett Jones;Jürgen Scheller;Stefan Rose-John

  • ADAM17: a molecular switch to control inflammation and tissue regeneration

    Jürgen Scheller;Athena Chalaris;Christoph Garbers;Stefan Rose-John

  • Production of spider silk proteins in tobacco and potato

    Jürgen Scheller;Karl-Heinz Gührs;Frank Grosse;Udo Conrad

  • The IL-6/sIL-6R complex as a novel target for therapeutic approaches.

    Stefan Rose-John;Georg H Waetzig;Jürgen Scheller;Joachim Grötzinger

  • G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation

    Christian Sina;Olga Gavrilova;Matti Förster;Andreas Till

  • Plasticity and cross-talk of interleukin 6-type cytokines.

    Christoph Garbers;Heike M. Hermanns;Fred Schaper;Gerhard Müller-Newen

  • Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

    Athena Chalaris;Björn Rabe;Krzysztof Paliga;Hans Lange

  • Interleukin-6 and its receptor: from bench to bedside.

    Jürgen Scheller;Stefan Rose-John

  • IL-6 transsignaling: the in vivo consequences.

    Simon A Jones;Peter J Richards;Jürgen Scheller;Stefan Rose-John

  • The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.

    Athena Chalaris;Christoph Garbers;Björn Rabe;Stefan Rose-John

  • Interleukin-6: from basic biology to selective blockade of pro-inflammatory activities.

    Jürgen Scheller;Christoph Garbers;Stefan Rose-John

  • Transgenic blockade of interleukin 6 transsignaling abrogates inflammation

    Bjorn Rabe;Athena Chalaris;Ulrike May;Georg H. Waetzig

  • Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

    Athena Chalaris;Nina Adam;Christian Sina;Philip Rosenstiel

  • Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination

    Rohit Prakash;Dominik Satory;Eloïse Dray;Almas Papusha

  • Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain

    Iain L. Campbell;Maria Erta;Sue Ling Lim;Ricardo Frausto

  • Cutting Edge: Trans-Signaling via the Soluble IL-6R Abrogates the Induction of FoxP3 in Naive CD4+CD25− T Cells

    Sabine Dominitzki;Massimo C. Fantini;Clemens Neufert;Alexei Nikolaev

  • Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.

    Satoshi Matsumoto;Taeko Hara;Keiichi Mitsuyama;Mayuko Yamamoto

  • Elastin-like polypeptides revolutionize recombinant protein expression and their biomedical application.

    Doreen M. Floss;Kai Schallau;Stefan Rose-John;Udo Conrad

Frequent Co-Authors

Stefan Rose-John
Stefan Rose-John Kiel University
Joachim Grötzinger
Joachim Grötzinger Kiel University
Udo Conrad
Udo Conrad Institute of Plant Genetics and Crop Plant Research
Simon Arnett Jones
Simon Arnett Jones Cardiff University
Philipp A. Lang
Philipp A. Lang Heinrich Heine University Düsseldorf
Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Philip Rosenstiel
Philip Rosenstiel Kiel University
Sergei A. Nedospasov
Sergei A. Nedospasov Lomonosov Moscow State University
Klaus Pfeffer
Klaus Pfeffer Heinrich Heine University Düsseldorf
Iain L. Campbell
Iain L. Campbell University of Sydney

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Microbiology opens multiple career opportunities, especially when combined with health information management and medical coding skills. For graduates interested in the intersection of healthcare and technology, exploring health information management jobs salary can provide insight into rewarding career paths. These roles often require specialized knowledge available through online health information management programs cahiim accredited, ensuring quality education accredited by the Commission on Accreditation for Health Informatics and Information Management Education (CAHIIM).

For those seeking quicker certification routes, accredited fast medical billing and coding certificate online programs offer accelerated pathways to enter the healthcare administration field. These certifications complement a microbiology background by providing practical administrative skills in healthcare settings.

Moreover, the rise of digital learning has expanded access to medical education, including various medical programs online that allow students to pursue advanced healthcare degrees flexibly. Combining a microbiology degree with such online credentials can enhance employability and open doors in laboratory management, clinical research, and health informatics.

Best Scientists Citing Jürgen Scheller

Trending Scientists