D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 61 Citations 19,203 157 World Ranking 5116 National Ranking 369

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cytokine
  • Immune system

Jürgen Scheller mainly focuses on Cell biology, Cytokine, Immunology, Interleukin 6 and Inflammation. His studies deal with areas such as Transgene, Receptor, Molecular biology, Fusion protein and Cytotoxic T cell as well as Cell biology. His research combines Signal transduction and Cytokine.

Jürgen Scheller mostly deals with Immune system in his studies of Immunology. He is involved in the study of Interleukin 6 that focuses on Glycoprotein 130 in particular. As a member of one scientific family, Jürgen Scheller mostly works in the field of Inflammation, focusing on Tumor necrosis factor alpha and, on occasion, Intestinal mucosa, Pathology, Proinflammatory cytokine and Ectodomain.

His most cited work include:

  • The pro- and anti-inflammatory properties of the cytokine interleukin-6 (1767 citations)
  • IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer (1523 citations)
  • Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. (548 citations)

What are the main themes of his work throughout his whole career to date?

Jürgen Scheller spends much of his time researching Cell biology, Glycoprotein 130, Receptor, Interleukin 6 and Signal transduction. His studies in Cell biology integrate themes in fields like T cell and Fusion protein. His Receptor research includes themes of Molecular biology, Endocrinology and Cytokine.

The study incorporates disciplines such as Tumor necrosis factor alpha and In vivo in addition to Cytokine. His research in Interleukin 6 intersects with topics in Proinflammatory cytokine, Interleukin and Cancer research. As a part of the same scientific family, Jürgen Scheller mostly works in the field of Signal transduction, focusing on Internal medicine and, on occasion, Cardiology.

He most often published in these fields:

  • Cell biology (44.83%)
  • Glycoprotein 130 (33.00%)
  • Receptor (32.02%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (44.83%)
  • Receptor (32.02%)
  • Signal transduction (30.54%)

In recent papers he was focusing on the following fields of study:

Jürgen Scheller mainly investigates Cell biology, Receptor, Signal transduction, Cytokine and Glycoprotein 130. Jürgen Scheller has researched Cell biology in several fields, including Interleukin and Fusion protein. His Receptor research includes themes of Interleukin 6, Molecular biology and Green fluorescent protein.

Jürgen Scheller combines subjects such as Interleukin 12 and Cancer research with his study of Signal transduction. His Cytokine study combines topics from a wide range of disciplines, such as Ciliary neurotrophic factor and Immune system. The study incorporates disciplines such as Phenocopy, Transfection, Interleukin-6 receptor, Regeneration and Penetrance in addition to Glycoprotein 130.

Between 2015 and 2021, his most popular works were:

  • Synthetic cytokine receptors transmit biological signals using artificial ligands. (75 citations)
  • The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling (54 citations)
  • SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy. (53 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cytokine
  • Immune system

His primary areas of investigation include Cell biology, Signal transduction, Interleukin, Cytokine and Glycoprotein 130. His studies in Cell biology integrate themes in fields like Proinflammatory cytokine, Cancer research and Hepatic stellate cell. His Signal transduction research includes elements of Receptor, Ectodomain and Fusion protein.

His Interleukin study incorporates themes from Carcinogenesis, PI3K/AKT/mTOR pathway, Ischemia and MAPK/ERK pathway. His Cytokine research incorporates elements of Extracellular, Tenascin C, 5'-nucleotidase and Matricellular protein. Interleukin 6 covers he research in Glycoprotein 130.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The pro- and anti-inflammatory properties of the cytokine interleukin-6

Jürgen Scheller;Athena Chalaris;Dirk Schmidt-Arras;Stefan Rose-John.
Biochimica et Biophysica Acta (2011)

2729 Citations

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei Grivennikov;Eliad Karin;Janos Terzic;Janos Terzic;Daniel Mucida.
Cancer Cell (2009)

2011 Citations

Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.

Stefan Rose‐John;Jürgen Scheller;Greg Elson;Simon A. Jones.
Journal of Leukocyte Biology (2006)

763 Citations

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

Simon Arnett Jones;Jürgen Scheller;Stefan Rose-John.
Journal of Clinical Investigation (2011)

648 Citations

ADAM17: a molecular switch to control inflammation and tissue regeneration

Jürgen Scheller;Athena Chalaris;Christoph Garbers;Stefan Rose-John.
Trends in Immunology (2011)

464 Citations

The IL-6/sIL-6R complex as a novel target for therapeutic approaches.

Stefan Rose-John;Georg H Waetzig;Jürgen Scheller;Joachim Grötzinger.
Expert Opinion on Therapeutic Targets (2007)

434 Citations

Production of spider silk proteins in tobacco and potato

Jürgen Scheller;Karl-Heinz Gührs;Frank Grosse;Udo Conrad.
Nature Biotechnology (2001)

419 Citations

G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation

Christian Sina;Olga Gavrilova;Matti Förster;Andreas Till.
Journal of Immunology (2009)

391 Citations

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

Athena Chalaris;Björn Rabe;Krzysztof Paliga;Hans Lange.
Blood (2007)

368 Citations

IL-6 transsignaling: the in vivo consequences.

Simon A Jones;Peter J Richards;Jürgen Scheller;Stefan Rose-John.
Journal of Interferon and Cytokine Research (2005)

361 Citations

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