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D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
55831
World Ranking
6096
National Ranking
434

Overview

Florian R. Greten is affiliated with Goethe University Frankfurt in Germany. Their research primarily focuses on the intersecting fields of medicine and biochemistry, genetics, and molecular biology, with an emphasis on oncology, immunology, and cancer research.

Their work addresses several core areas within cancer biology, including cancer immunotherapy and biomarkers, the role of immune cells in cancer, and cancer cell metastasis. Additional topics of interest encompass immune cell function and interaction, ferroptosis and cancer prognosis, genetic factors in colorectal cancer, and cancer genomics and diagnostics.

Frequent collaborators in their research include Henner F. Farin, Marina Pešić, Kilian B. Kennel, Adele M. Nicolas, and Mohammed H. Mosa. This network of coauthors supports a substantial body of work contributing to understanding cancer biology and immunology.

Publications by Florian R. Greten have appeared repeatedly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Reviews. Cancer, Cancer Cell, Gut, and Cancer Research. These outlets reflect a focus on both emerging research and well-established journals in cancer and immunology fields.

Recent scientific papers authored or coauthored by Florian R. Greten include:

  • A framework for advancing our understanding of cancer-associated fibroblasts, 2020, Nature Reviews. Cancer
  • The inflammatory pathogenesis of colorectal cancer, 2021, Nature Reviews. Immunology
  • Fructose stimulated de novo lipogenesis is promoted by inflammation, 2020, Nature Metabolism
  • Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer, 2022, Cancer Cell
  • Inflammation: the incubator of the tumor microenvironment, 2022, Trends in Cancer

Best Publications

  • Immunity, Inflammation, and Cancer

    Sergei I. Grivennikov;Florian R. Greten;Michael Karin

  • NF-kappaB: linking inflammation and immunity to cancer development and progression.

    Michael Karin;Florian R. Greten

  • A framework for advancing our understanding of cancer-associated fibroblasts

    Erik Sahai;Igor Astsaturov;Edna Cukierman;David G. DeNardo

  • Inflammation and Cancer: Triggers, Mechanisms, and Consequences.

    Florian R. Greten;Florian R. Greten;Sergei I. Grivennikov

  • NF-κB in cancer: from innocent bystander to major culprit

    Michael Karin;Yixue Cao;Florian R. Greten;Zhi-Wei Li

  • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.

    Florian R. Greten;Lars Eckmann;Tim F. Greten;Jin Mo Park

  • IKK-beta links inflammation to obesity-induced insulin resistance.

    Melek C. Arkan;Andrea L. Hevener;Florian R. Greten;Shin Maeda

  • Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

    Uwe Senftleben;Yixue Cao;Gutian Xiao;Florian R. Greten

  • Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

    Sarah Schwitalla;Alexander A. Fingerle;Patrizia Cammareri;Tim Nebelsiek

  • gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

    Julia Bollrath;Toby J Phesse;Vivian A von Burstin;Tracy Putoczki

  • NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

    Florian R. Greten;Florian R. Greten;Melek C. Arkan;Melek C. Arkan;Julia Bollrath;Li-Chung Hsu

  • IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

    Matjaz Rokavec;Meryem Gülfem Öner;Huihui Li;Rene Jackstadt

  • The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion.

    Lee Wei Chen;Laurence Egan;Zhi Wei Li;Florian R. Greten

  • Macrophage Apoptosis by Anthrax Lethal Factor Through p38 MAP Kinase Inhibition

    Jin Mo Park;Florian R. Greten;Zhi-Wei Li;Michael Karin

  • Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

    Colby Zaph;Amy E. Troy;Betsy C. Taylor;Lisa D. Berman-Booty

  • IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development

    Yixue Cao;Giuseppina Bonizzi;Tiffany N. Seagroves;Florian R. Greten

  • The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer

    Florian R. Greten;Michael Karin

  • High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity

    Manon D. Schulz;Çiğdem Atay;Jessica Heringer;Franziska K. Romrig

  • IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

    Julia Bollrath;Florian R. Greten

  • The inflammatory pathogenesis of colorectal cancer.

    Mark Schmitt;Florian R. Greten;Florian R. Greten

Frequent Co-Authors

Michael Karin
Michael Karin University of California, San Diego
Roland M. Schmid
Roland M. Schmid Technical University of Munich
Lars Eckmann
Lars Eckmann University of California, San Diego
Guido Adler
Guido Adler University of Ulm
Jürgen Ruland
Jürgen Ruland Technical University of Munich
Matthias Ernst
Matthias Ernst La Trobe University
Markus F. Neurath
Markus F. Neurath University of Erlangen-Nuremberg
Tim F. Greten
Tim F. Greten National Institutes of Health
Makoto Mark Taketo
Makoto Mark Taketo Kyoto University
Stefan Rose-John
Stefan Rose-John Kiel University

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