What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cancer
Jürgen Ruland focuses on Cell biology, Signal transduction, Cancer research, Innate immune system and Immunology.
His work deals with themes such as T cell, T-cell receptor and Transcription factor, which intersect with Cell biology.
Jürgen Ruland focuses mostly in the field of T cell, narrowing it down to matters related to Paracaspase and, in some cases, MALT1.
His study in Signal transduction is interdisciplinary in nature, drawing from both Pyrin domain and Inflammasome.
His studies in Cancer research integrate themes in fields like B cell, Phosphatidylinositol, Phosphorylation, BCL10 and PTEN.
His work carried out in the field of Immunology brings together such families of science as Mutation, Disease gene identification and Genetics.
His most cited work include:
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN (2101 citations)
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN (2101 citations)
- DNA damage-induced activation of p53 by the checkpoint kinase Chk2. (1119 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Cancer research, Immunology, Signal transduction and Immune system are his primary areas of study.
His Cell biology research incorporates themes from Receptor and Transcription factor.
His studies in Cancer research integrate themes in fields like MALT1, T cell, B cell and BCL10, Lymphoma.
His study explores the link between MALT1 and topics such as Paracaspase that cross with problems in Regulator.
Innate immune system, Inflammasome, Immunity, Inflammation and Acquired immune system are among the areas of Immunology where Jürgen Ruland concentrates his study.
His study in Innate immune system is interdisciplinary in nature, drawing from both Chemokine, Microbiology and Virology.
He most often published in these fields:
- Cell biology (42.42%)
- Cancer research (47.98%)
- Immunology (34.34%)
What were the highlights of his more recent work (between 2018-2021)?
- Cancer research (47.98%)
- Cell biology (42.42%)
- Immune system (23.23%)
In recent papers he was focusing on the following fields of study:
Jürgen Ruland spends much of his time researching Cancer research, Cell biology, Immune system, Receptor and Immunology.
His studies deal with areas such as Protein kinase B, Tumor microenvironment, B cell, Metastasis and Colorectal cancer as well as Cancer research.
His biological study spans a wide range of topics, including Suppressor, PI3K/AKT/mTOR pathway and Lymphoma.
His Cell biology research is multidisciplinary, incorporating perspectives in T cell, Oxidative phosphorylation, RNA interference, Metabolic pathway and Interactome.
When carried out as part of a general Immune system research project, his work on Acquired immune system is frequently linked to work in Volumetric imaging, therefore connecting diverse disciplines of study.
In general Receptor study, his work on Innate immune system often relates to the realm of Fusion protein, thereby connecting several areas of interest.
Between 2018 and 2021, his most popular works were:
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
- CARD-BCL-10-MALT1 signalling in protective and pathological immunity. (33 citations)
- RIG-I activation is critical for responsiveness to checkpoint blockade. (30 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cancer
- Immune system
His scientific interests lie mostly in Immune system, Cell biology, T-cell receptor, Innate immune system and Antigen.
Jürgen Ruland works mostly in the field of Immune system, limiting it down to topics relating to Tissue homeostasis and, in certain cases, Syk, Interferon, Proto-oncogene tyrosine-protein kinase Src, MAPK/ERK pathway and Function, as a part of the same area of interest.
His work blends Cell biology and Genome editing studies together.
His T-cell receptor study integrates concerns from other disciplines, such as MALT1, Adoptive cell transfer, Melanoma, Gene and Immunotherapy.
In the field of Receptor and Immunology Jürgen Ruland studies Innate immune system.
His research integrates issues of Tumor microenvironment, RIG-I, Cancer research and Blockade in his study of Antigen.
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