Jürgen Ruland

Overview

Best Publications

• Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

  Vuk Stambolic;Vuk Stambolic;Akira Suzuki;Akira Suzuki;José Luis de la Pompa;José Luis de la Pompa

  3274
  Citations

• DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

  Atsushi Hirao;Young-Yun Kong;Shuhei Matsuoka;Andrew Wakeham

  1721
  Citations

• Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

  Salomé LeibundGut-Landmann;Olaf Groß;Matthew J Robinson;Fabiola Osorio

  1419
  Citations

• The SYK tyrosine kinase: a crucial player in diverse biological functions.

  Attila Mócsai;Jürgen Ruland;Victor L. J. Tybulewicz

  1402
  Citations

• Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.

  Olaf Gross;Olaf Gross;Hendrik Poeck;Michael Bscheider;Catherine Dostert

  1085
  Citations

• Guidelines for the use of flow cytometry and cell sorting in immunological studies

  Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  1078
  Citations

• Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

  Olaf Gross;Andreas Gewies;Katrin Finger;Martin Schäfer

  1021
  Citations

• Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

  Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  914
  Citations

• A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections

  Erik-Oliver Glocker;Andre Hennigs;Mohammad Nabavi;Alejandro A. Schäffer

  909
  Citations

• The target landscape of clinical kinase drugs

  Susan Klaeger;Susan Klaeger;Stephanie Heinzlmeir;Stephanie Heinzlmeir;Mathias Wilhelm;Harald Polzer;Harald Polzer

  775
  Citations

• Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

  Jürgen Ruland;Jürgen Ruland;Gordon S Duncan;Gordon S Duncan;Andrew Elia;Andrew Elia;Ivan del Barco Barrantes;Ivan del Barco Barrantes

  687
  Citations

• Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1|[beta]| production

  Hendrik Poeck;Michael Bscheider;Olaf Gross;Olaf Gross;Katrin Finger

  646
  Citations

• Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

  Matthew J. Robinson;Fabiola Osorio;Marcela Rosas;Rui P. Freitas

  571
  Citations

• Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications.

  Philipp J. Jost;Jürgen Ruland

  559
  Citations

• Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.

  Hanne Schoenen;Barbara Bodendorfer;Kelly Hitchens;Silvia Manzanero

  553
  Citations

• 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

  Poeck H;Besch R;Maihoefer C;Maihoefer C;Renn M

  463
  Citations

• Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

  Jürgen Ruland;Jürgen Ruland;Gordon S Duncan;Andrew Wakeham;Tak W Mak

  449
  Citations

• K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

  Christina J. Groß;Ritu Mishra;Katharina S. Schneider;Guillaume Médard

  446
  Citations

• Return to homeostasis: downregulation of NF-κB responses

  Jürgen Ruland

  410
  Citations

• The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

  Rune Busk Damgaard;Ueli Nachbur;Ueli Nachbur;Ueli Nachbur;Monica Yabal;Wendy Wei-Lynn Wong;Wendy Wei-Lynn Wong

  396
  Citations