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Immunology

D-Index
83
Citations
21605
World Ranking
1467
National Ranking
6

Overview

Gerhard Walzl is affiliated with Stellenbosch University in South Africa and has a prominent research profile in the field of Medicine, focusing extensively on Infectious Diseases, Epidemiology, Immunology, Surgery, and Molecular Biology. Their work centers primarily on tuberculosis and related infectious diseases, with a substantial volume of publications contributing to these areas.

The main topics covered in their research include:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Infectious Diseases and Tuberculosis
  • Diagnosis and treatment of tuberculosis
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Pneumonia and Respiratory Infections
  • Immune cells in cancer

Walzl has published in a variety of scientific journals, with frequent appearances in these venues:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Tuberculosis
  • SSRN Electronic Journal
  • Clinical Infectious Diseases

Significant recent publications by Walzl include:

  • RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response (2020) - Scientific Reports
  • Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial (2021) - The Lancet Infectious Diseases
  • S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis (2020) - Journal of Clinical Investigation
  • Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise (2024) - The Lancet Respiratory Medicine
  • Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results (2021) - Clinical Infectious Diseases

Frequent coauthors collaborating with Walzl include:

  • Stephanus T. Malherbe
  • Novel N. Chegou
  • Thomas J. Scriba
  • Nelita du Plessis
  • Mark Hatherill

Their contributions mainly focus on research that advances understanding of host-pathogen interactions in tuberculosis, identification of biomarkers for disease risk and treatment response, as well as clinical trials examining tuberculosis preventive therapies.

Best Publications

  • A blood RNA signature for tuberculosis disease risk: a prospective cohort study.

    Daniel E Zak;Adam Penn-Nicholson;Thomas J Scriba;Ethan Thompson

  • Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice

    Robert S Wallis;Madhukar Pai;Madhukar Pai;Dick Menzies;Dick Menzies;T Mark Doherty

  • Immunological biomarkers of tuberculosis.

    Gerhard Walzl;Katharina Ronacher;Willem Hanekom;Thomas J. Scriba

  • Distinct, Specific IL-17- and IL-22-Producing CD4+ T Cell Subsets Contribute to the Human Anti-Mycobacterial Immune Response

    Thomas J. Scriba;Barbara Kalsdorf;Deborah-Ann Abrahams;Fatima Isaacs

  • Genital Inflammation and the Risk of HIV Acquisition in Women

    Lindi Masson;Lindi Masson;Jo Ann S. Passmore;Jo Ann S. Passmore;Lenine J. Liebenberg;Lise Werner

  • Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies

    Simon Tiberi;Nelita du Plessis;Gerhard Walzl;Michael J Vjecha

  • Human gene expression profiles of susceptibility and resistance in tuberculosis

    Jeroen Maertzdorf;D. Repsilber;Shreemanta K. Parida;K. Stanley

  • Tuberculosis: advances and challenges in development of new diagnostics and biomarkers

    Gerhard Walzl;Gerhard Walzl;Ruth McNerney;Nelita du Plessis;Nelita du Plessis;Matthew Bates;Matthew Bates

  • Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis

    Sara Suliman;Ethan G. Thompson;Jayne Sutherland;January Weiner rd

  • Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response.

    Jacqueline M. Cliff;Ji-Sook Lee;Nicholas Constantinou;Jang-Eun Cho

  • Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression.

    Lindi Roberts;Jo-Ann S Passmore;Carolyn Williamson;Francesca Little

  • Biomarkers of Inflammation, Immunosuppression and Stress with Active Disease Are Revealed by Metabolomic Profiling of Tuberculosis Patients

    January Weiner;Shreemanta K Parida;Jeroen Maertzdorf;Gillian F Black

  • A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes

    Roshni Roy Chowdhury;Francesco Vallania;Qianting Yang;Cesar Joel Lopez Angel

  • Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study

    Lindi Masson;Koleka Mlisana;Francesca Little;Lise Werner

  • Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: Preliminary report

    Novel N Chegou;Gillian F Black;Martin Kidd;Paul D van Helden

  • Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection.

    Graham R. Stewart;Valerie A. Snewin;Gerhard Walzl;Tracy Hussell

  • Host blood RNA signatures predict the outcome of tuberculosis treatment

    Ethan G Thompson;Ying Du;Stephanus T Malherbe;Smitha Shankar

  • An evaluation of commercial fluorescent bead-based luminex cytokine assays.

    Joel Fleury Djoba Siawaya;Teri Roberts;Chantal Babb;Gillian Black

  • Increased Frequency of Myeloid-derived Suppressor Cells during Active Tuberculosis and after Recent Mycobacterium tuberculosis Infection Suppresses T-Cell Function

    Nelita du Plessis;Laurianne Loebenberg;Magdalena Kriel;Florian von Groote-Bidlingmaier

  • Beyond the IFN-γ horizon: biomarkers for immunodiagnosis of infection with Mycobacterium tuberculosis

    Novel N Chegou;Jan Heyckendorf;Gerhard Walzl;Christoph Lange;Christoph Lange

  • Influenza Virus Lung Infection Protects from Respiratory Syncytial Virus–Induced Immunopathology

    Gerhard Walzl;Sabrina Tafuro;Paul Moss;Peter J.M. Openshaw

  • Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[ 18 F]fluoro- D -glucose positron emission and computed tomography

    Hanif Esmail;Hanif Esmail;Hanif Esmail;Rachel P Lai;Maia Lesosky;Katalin A Wilkinson;Katalin A Wilkinson

Frequent Co-Authors

Thomas J. Scriba
Thomas J. Scriba University of Cape Town
Hazel M. Dockrell
Hazel M. Dockrell London School of Hygiene & Tropical Medicine
Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
Tom H. M. Ottenhoff
Tom H. M. Ottenhoff Leiden University Medical Center
Paul D. van Helden
Paul D. van Helden Stellenbosch University
Willem A. Hanekom
Willem A. Hanekom University College London
Laura E. Via
Laura E. Via National Institutes of Health
Gerard Tromp
Gerard Tromp Stellenbosch University
Clifton E. Barry
Clifton E. Barry National Institute of Allergy and Infectious Diseases

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