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Best Female Scientists
2025

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Best Female Scientists

D-Index
121
Citations
92510
World Ranking
514
National Ranking
54

Immunology

D-Index
124
Citations
97357
World Ranking
291
National Ranking
26

Medicine

D-Index
124
Citations
97439
World Ranking
3147
National Ranking
316

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2008 - Fellow of the Royal Society, United Kingdom
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Anne O'Garra is affiliated with The Francis Crick Institute in the United Kingdom, focusing on research within the fields of Medicine and Immunology and Microbiology. Their work encompasses multiple subfields including Immunology, Infectious Diseases, Epidemiology, Surgery, and Molecular Biology.

Their research addresses key topics such as Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, IL-33, ST2, and ILC Pathways, Immune Cell Function and Interaction, Immune cells in cancer, Immune Response and Inflammation, and Diagnosis and treatment of tuberculosis.

Recent publications by Anne O'Garra include:

  • Host-directed immunotherapy of viral and bacterial infections: past, present and future, 2022, Nature reviews. Immunology
  • Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis, 2020, Nature Communications
  • Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis, 2020, Nature Immunology
  • Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis, 2021, The Journal of Experimental Medicine
  • Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data, 2021, Nature Communications

Frequent co-authors collaborating with Anne O'Garra include:

  • William J. Branchett (9 collaborations)
  • Probir Chakravarty (6 collaborations)
  • Simon L. Priestnall (4 collaborations)
  • Alejandro Suárez-Bonnet (4 collaborations)
  • Kaori L. Fonseca (4 collaborations)

Their work appears regularly in several publication venues such as:

  • Wellcome Open Research (4 publications)
  • Nature Communications (3 publications)
  • The Journal of Experimental Medicine (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • Nature Immunology (2 publications)

Anne O'Garra's scientific expertise is supported by several honors including being awarded Fellow of the Royal Society, United Kingdom in 2008, Fellow of the American Association for the Advancement of Science (AAAS) in 2006, and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Interleukin-10 and the interleukin-10 receptor.

    Moore Kw;de Waal Malefyt R;Coffman Rl;O'Garra A

  • A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

    Hervé Groux;Anne O'Garra;Mike Bigler;Matthieu Rouleau

  • IL-10 inhibits cytokine production by activated macrophages.

    D F Fiorentino;A Zlotnik;T R Mosmann;M Howard

  • Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

    Chyi Song Hsieh;Steven E. Macatonia;Catherine S. Tripp;Stanley F. Wolf

  • The regulation of IL-10 production by immune cells

    Margarida Saraiva;Anne O'Garra

  • Type I interferons in infectious disease.

    Finlay McNab;Katrin Mayer-Barber;Alan Sher;Andreas Wack

  • IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.

    D F Fiorentino;A Zlotnik;P Vieira;T R Mosmann

  • Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets

    Anne O'Garra

  • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

    Matthew P. R. Berry;Christine M. Graham;Finlay W. McNab;Zhaohui Xu

  • Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

    S. E. Macatonia;N. A. Hosken;M. Litton;P. Vieira

  • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

    Franck J. Barrat;Daniel J. Cua;André Boonstra;David F. Richards

  • The Immune Response in Tuberculosis

    Anne O'Garra;Paul S. Redford;Finlay W. McNab;Chloe I. Bloom

  • 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells.

    André Boonstra;Franck J. Barrat;Chad Crain;Victoria L. Heath

  • Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology.

    Carine Asselin-Paturel;Andre Boonstra;Marc Dalod;Isabelle Durand

  • Regulatory T cells and mechanisms of immune system control.

    Anne O'Garra;Paulo Vieira

  • Biology and therapeutic potential of interleukin-10.

    Margarida Saraiva;Margarida Saraiva;Paulo Vieira;Paulo Vieira;Paulo Vieira;Anne O’Garra;Anne O’Garra

  • BIOLOGICAL PROPERTIES OF INTERLEUKIN-10

    Maureen Howard;Anne O'Garra

  • Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma

    Catherine Hawrylowicz;A O'Garra

  • IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation

    Wenjun Ouyang;Anne O’Garra

  • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system.

    Chyi-Song Hsieh;Amy B. Heimberger;Jennifer S. Gold;Anne O'Garra

  • The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.

    Nancy A. Hosken;Kazuko Shibuya;Andrew W. Heath;Kenneth M. Murphy

  • IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB

    Douglas Robinson;Kazuko Shibuya;Alice Mui;Francesca Zonin

  • Interleukin-10.

    Unknown

Frequent Co-Authors

Robert J. Wilkinson
Robert J. Wilkinson The Francis Crick Institute
Maureen Howard
Maureen Howard Stanford University
Damien Chaussabel
Damien Chaussabel Sidra Medical and Research Center
Katalin A. Wilkinson
Katalin A. Wilkinson The Francis Crick Institute
Kenneth M. Murphy
Kenneth M. Murphy Washington University in St. Louis
Marc Lipman
Marc Lipman Royal Free London NHS Foundation Trust
Virginia Pascual
Virginia Pascual Cornell University
Giorgio Trinchieri
Giorgio Trinchieri National Institutes of Health
Douglas S. Robinson
Douglas S. Robinson University College Hospital

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