Douglas S. Robinson

Overview

Best Publications

• Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

  D. S. Robinson;Q. Hamid;Sun Ying;A. Tsicopoulos

  3669
  Citations

• Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease.

  Eleanor M Ling;Eleanor M Ling;Trevor Smith;X Dao Nguyen;Carol Pridgeon

  1082
  Citations

• Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity.

  Sun Ying;Brian O’Connor;Jonathan Ratoff;Qiu Meng

  1035
  Citations

• Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

  Patrick Flood-Page;Andrew Menzies-Gow;Simon Phipps;Sun Ying

  1014
  Citations

• Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway

  Patrick T. Flood-Page;Andrew N. Menzies-Gow;A. Barry Kay;Douglas S. Robinson

  980
  Citations

• IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB

  Douglas Robinson;Kazuko Shibuya;Alice Mui;Francesca Zonin

  925
  Citations

• A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.

  Patrick Flood-Page;Cheri Swenson;Isidore Faiferman;John Matthews

  904
  Citations

• Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma

  D. Robinson;Qutayba Hamid;A. Bentley;Sun Ying

  894
  Citations

• The role of T lymphocytes in the pathogenesis of asthma

  Mark Larché;Douglas S. Robinson;A.Barry Kay

  886
  Citations

• Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients.

  Emmanuel Xystrakis;Siddharth Kusumakar;Sandra Boswell;Emma Peek

  783
  Citations

• Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent.

  Jennifer Kearley;Jane E. Barker;Douglas S. Robinson;Clare M. Lloyd

  700
  Citations

• Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells.

  Sun Ying;Douglas S. Robinson;Qiu Meng;James Rottman

  632
  Citations

• Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics

  Sun Ying;Qiu Meng;K. Zeibecoglou;D. S. Robinson

  602
  Citations

• Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.

  S Ying;M Humbert;J Barkans;C J Corrigan

  591
  Citations

• IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity.

  M Humbert;S R Durham;S Ying;P Kimmitt

  589
  Citations

• Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness.

  A. M. Bentley;G. Menz;Chr. Storz;D. S. Robinson

  576
  Citations

• The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences.

  Marc Humbert;Günter Menz;Sun Ying;Christopher J Corrigan

  496
  Citations

• The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

  Unknown

  481
  Citations

• Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics

  A. M. Bentley;Qiu Meng;D. S. Robinson;Q. Hamid

  467
  Citations

• A role for eosinophils in airway remodelling in asthma

  A. Barry Kay;Simon Phipps;Simon Phipps;Douglas S. Robinson;Douglas S. Robinson

  453
  Citations

• Tregs and allergic disease

  Douglas S. Robinson;Mark Larché;Stephen R. Durham

  445
  Citations

• Prednisolone Treatment in Asthma Is Associated with Modulation of Bronchoalveolar Lavage Cell Interleukin-4, Interleukin-5, and Interferon-γ Cytokine Gene Expression

  D. Robinson;Q. Hamid;Sun Ying;A. Bentley

  435
  Citations