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Immunology

D-Index
54
Citations
11865
World Ranking
3876
National Ranking
98

Overview

Mark Larché is affiliated with McMaster University in Canada and has a research focus primarily in the field of Medicine, with an emphasis on Immunology and Allergy. Their work spans several subfields including Physiology, Hematology, Dermatology, and Infectious Diseases.

The scientist's prolific output includes research on a variety of topics related to allergic and immune system disorders. Their main topics of study include:

  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Food Allergy and Anaphylaxis Research
  • Dermatology and Skin Diseases
  • Platelet Disorders and Treatments
  • Blood groups and transfusion
  • Long-Term Effects of COVID-19

Mark Larché has published extensively in venues that are well recognized within allergy and immunology fields. Frequent publication venues include:

  • Allergy
  • Journal of Allergy and Clinical Immunology
  • European Journal Of Haematology
  • Viruses
  • Nature

Some of their recent papers include:

  • One hundred and ten years of Allergen Immunotherapy: A journey from empiric observation to evidence, 2021, Allergy
  • Comparison of house dust mite sensitization profiles in allergic adults from Canada, Europe, South Africa and USA, 2021, Allergy
  • Technical standards in allergen exposure chambers worldwide - an EAACI Task Force Report, 2021, Allergy
  • Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen, 2020, Journal of Allergy and Clinical Immunology
  • T cell-mediated autoimmunity in immune thrombocytopenia, 2021, European Journal Of Haematology

Collaboration forms a notable aspect of Larché's work, with frequent co-authors including:

  • Ishac Nazy
  • Stephen R. Durham
  • Pascal Hickey
  • Elena Tonti
  • Allison Kennedy

Best Publications

  • Immunological mechanisms of allergen-specific immunotherapy

    Mark Larché;Mark Larché;Cezmi A. Akdis;Rudolf Valenta

  • The role of T lymphocytes in the pathogenesis of asthma

    Mark Larché;Douglas S. Robinson;A.Barry Kay

  • Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.

    S Ying;M Humbert;J Barkans;C J Corrigan

  • Tregs and allergic disease

    Douglas S. Robinson;Mark Larché;Stephen R. Durham

  • Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial.

    W L G Oldfield;M Larché;A B Kay

  • Peptide-based therapeutic vaccines for allergic and autoimmune diseases.

    Mark Larché;David C Wraith

  • Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions.

    Brigitte M. Haselden;A. Barry Kay;Mark Larché

  • Functional rather than immunoreactive levels of IgG4 correlate closely with clinical response to grass pollen immunotherapy

    M. H. Shamji;C. Ljørring;J. N. Francis;M. A Calderon

  • Regulatory T Cells in Allergy and Asthma

    Mark Larché

  • Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression

    John D M Campbell;Karen F. Buckland;Sarah J. McMillan;Jennifer Kearley

  • Development of Primary and Secondary Immune Responses to Mouse Monoclonal Antibodies Used in the Diagnosis and Therapy of Malignant Neoplasms

    Nigel S. Courtenay-Luck;Agamemnon A. Epenetos;Richard Moore;Mark Larche

  • Fel d 1–derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: A randomized, placebo-controlled study

    Deepen Patel;Peter Couroux;Pascal Hickey;Anne Marie Salapatek

  • Development and preliminary clinical evaluation of a peptide immunotherapy vaccine for cat allergy.

    Margitta Worm;Hae-Hyuk Lee;Jörg Kleine-Tebbe;Roderick P. Hafner

  • Allergen-Derived T Cell Peptide-Induced Late Asthmatic Reactions Precede the Induction of Antigen-Specific Hyporesponsiveness in Atopic Allergic Asthmatic Subjects

    William L. G. Oldfield;A. Barry Kay;Mark Larché

  • T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity.

    Adrienne Verhoef;Clare Alexander;A. Barry Kay;Mark Larché

  • The effect of rituximab on vaccine responses in patients with immune thrombocytopenia.

    Ishac Nazi;John G. Kelton;Mark Larché;Denis P. Snider

  • Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy.

    M. Tarzi;S. Klunker;C. Texier;A. Verhoef

  • The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses.

    Mohamed H. Shamji;Louisa K. Wilcock;Petra A. Wachholz;Rebecca J. Dearman

  • Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement

    Marek L. Kowalski;Ignacio Ansotegui;Werner Aberer;Mona Al-Ahmad

  • Costimulation Through CD86 Is Involved in Airway Antigen-Presenting Cell and T Cell Responses to Allergen in Atopic Asthmatics

    M Larché;S J Till;B M Haselden;J North

  • Changing of the guard

    Andy Wardlaw;Robyn O'Hehir;Qutayba A Hamid;Chris Corrigan

Frequent Co-Authors

A. B. Kay
A. B. Kay Imperial College London
Mark D. Inman
Mark D. Inman McMaster University
Paul M. O'Byrne
Paul M. O'Byrne McMaster University
Judah A. Denburg
Judah A. Denburg McMaster University
Douglas S. Robinson
Douglas S. Robinson University College Hospital
Gail M. Gauvreau
Gail M. Gauvreau McMaster University
Rudolf Valenta
Rudolf Valenta Medical University of Vienna
Christopher Corrigan
Christopher Corrigan King's College London
Ruby Pawankar
Ruby Pawankar Nippon Medical School
Jeffrey R. Brook
Jeffrey R. Brook University of Toronto

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