His scientific interests lie mostly in Micronucleus test, Micronucleus, Molecular biology, Genetics and Genotoxicity. His Micronucleus test research incorporates themes from Andrology, Pharmacology and In vivo. His Micronucleus study combines topics from a wide range of disciplines, such as Proliferation index, Mutagen, Immunology, Bone marrow and Mitomycin C.
His Molecular biology research is multidisciplinary, relying on both Mutation, Gene mutation, Mutant, DNA and Chromosome aberration. The concepts of his Genetics study are interwoven with issues in Poisson distribution and Analysis of variance. Toshio Sofuni works mostly in the field of Clastogen, limiting it down to topics relating to Chinese hamster and, in certain cases, Hamster, as a part of the same area of interest.
His primary areas of investigation include Molecular biology, Genetics, Micronucleus test, Mutant and Biochemistry. The various areas that he examines in his Molecular biology study include Clastogen, Gene, Genetically modified mouse, In vivo and Chinese hamster. His studies in In vivo integrate themes in fields like In vitro and Pharmacology.
His Micronucleus test research includes themes of Immunology, Bone marrow and Genotoxicity. His Mutant study integrates concerns from other disciplines, such as Mutation, Gene mutation and Transgene. His research in the fields of Enzyme, Carcinogen and Mutagenesis overlaps with other disciplines such as Strain.
His main research concerns Molecular biology, Micronucleus test, Genetics, Mutagen and Genotoxicity. His Molecular biology research is multidisciplinary, incorporating perspectives in Karyotype, Mutant, DNA damage and Gene mutation. His Micronucleus test research incorporates elements of Analysis of variance and Immunology.
His work on Chromosome aberration, Chromosomal translocation and DNA as part of his general Genetics study is frequently connected to Poisson regression, thereby bridging the divide between different branches of science. His study in Mutagen is interdisciplinary in nature, drawing from both Methyl methanesulfonate and Ethylnitrosourea. The study incorporates disciplines such as Bone marrow and Carcinogen in addition to Genotoxicity.
His primary areas of study are Micronucleus test, Genetics, Micronucleus, Molecular biology and Genotoxicity. His Micronucleus test study deals with the bigger picture of Toxicity. His Toxicity research integrates issues from Immunology, Pharmacology and In vivo.
His work carried out in the field of Genetics brings together such families of science as Poisson distribution and Analysis of variance. His Micronucleus study combines topics from a wide range of disciplines, such as Proliferation index, Coefficient of variation and Clastogen. Toshio Sofuni interconnects Mutation, Mutagen and Chromosome aberration in the investigation of issues within Molecular biology.
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Primary mutagenicity screening of food additives currently used in Japan
M. Ishidate;T. Sofuni;K. Yoshikawa;M. Hayashi.
Food and Chemical Toxicology (1984)
Report from the in vitro micronucleus assay working group
Micheline Kirsch-Volders;Toshio Sofuni;Marilyn Aardema;Silvio Albertini.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2003)
Multiple pathways for SOS-induced mutagenesis in Escherichia coli: An overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA
Su-Ryang Kim;Geneviéve Maenhaut-Michel;Masami Yamada;Yoshihiro Yamamoto.
Proceedings of the National Academy of Sciences of the United States of America (1997)
A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures
M. Ishidate;M.C. Harnois;T. Sofuni.
Mutation Research (1988)
Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group.
Takeshi Morita;Norihide Asano;Takumi Awogi;Yu F Sasaki.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (1997)
Report from the in vitro micronucleus assay working group
M. Kirsch-Volders;T. Sofuni;M. Aardema;S. Albertini.
Environmental and Molecular Mutagenesis (2000)
A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections.
T. Nohmi;M. Katoh;H. Suzuki;M. Matsui.
Environmental and Molecular Mutagenesis (1996)
Development of genotoxicity assay systems that use aquatic organisms
M Hayashi;T Ueda;K Uyeno;K Wada.
Mutation Research (1998)
Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project
Michael Fenech;Stefano Bonassi;Julie Turner;Cecilia Lando.
Mutation Research-genetic Toxicology and Environmental Mutagenesis (2003)
Specificity and sensitivity of Salmonella typhimurium YG1041 and YG1042 strains possessing elevated levels of both nitroreductase and acetyltransferase activity
Yuji Hagiwara;Masahiko Watanabe;Yoshimitsu Oda;Toshio Sofuni.
Mutation Research/environmental Mutagenesis and Related Subjects (1993)
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