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Takehiko Nohmi

Takehiko Nohmi

D-Index & Metrics

Molecular Biology

D-Index
67
Citations
16813
World Ranking
1568
National Ranking
131

Overview

Takehiko Nohmi is affiliated with Gifu University in Japan and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology and Cancer Research. Their research encompasses several specialized subfields including Oncology and Pathology and Forensic Medicine.

The scientist's work prominently addresses various topics such as DNA Repair Mechanisms, Carcinogens and Genotoxicity Assessment, and CRISPR and Genetic Engineering. They have also explored areas related to Genetically Modified Organisms Research, Genomics, phytochemicals, and oxidative stress, as well as genetic factors in colorectal cancer and Cancer Genomics and Diagnostics.

Frequent coauthors collaborate with Takehiko Nohmi on research projects; these include Kenichi Masumura, Shinji Takasu, Yuji Ishii, Takashi Umemura, and Mizuki Ohno. Their publications appear regularly in specific scientific venues, most notably the journal Genes and Environment, where they have published eight papers. Other notable venues include Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Archives of Toxicology, Food and Chemical Toxicology, and Genome Research.

Recent papers by Takehiko Nohmi include research on mutagenicity and oxidative stress with details as follows:

  • Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta (2021, Genes and Environment)
  • Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate (2020, Mutation Research/Genetic Toxicology and Environmental Mutagenesis)
  • Chromosome aberrations induced by the non-mutagenic carcinogen acetamide involve in rat hepatocarcinogenesis through micronucleus formation in hepatocytes (2021, Archives of Toxicology)
  • Oxidative stress accelerates intestinal tumorigenesis by enhancing 8-oxoguanine-mediated mutagenesis in MUTYH-deficient mice (2024, Genome Research)
  • Lack of In Vivo Mutagenicity of Acetamide in a 13-Week Comprehensive Toxicity Study Using F344 gpt Delta Rats (2020, Toxicological Sciences)

Best Publications

  • The Y-Family of DNA Polymerases

    Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman

  • Primary mutagenicity screening of food additives currently used in Japan

    M. Ishidate;T. Sofuni;K. Yoshikawa;M. Hayashi

  • The dinB Gene Encodes a Novel E. coli DNA Polymerase, DNA Pol IV, Involved in Mutagenesis

    Jérôme Wagner;Petr Gruz;Su-Ryang Kim;Masami Yamada

  • Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA

    Takashi Kohno;Kazuya Shinmura;Kazuya Shinmura;Masahiko Tosaka;Masachika Tani

  • Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

    Osamu Minowa;Tsuyoshi Arai;Masanori Hirano;Yoshiaki Monden

  • Multiple pathways for SOS-induced mutagenesis in Escherichia coli: An overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA

    Su-Ryang Kim;Geneviéve Maenhaut-Michel;Masami Yamada;Yoshihiro Yamamoto

  • RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation

    Takehiko Nohmi;John R. Battista;Lori A. Dodson;Graham C. Walker

  • Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivatives of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels

    Masahiko Watanabe;Motoi Ishidate;Takehiko Nohmi

  • Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

    Kiyomitsu Arai;Kiyomitsu Arai;Kazuhiro Morishita;Kazuya Shinmura;Takashi Kohno

  • A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections.

    T. Nohmi;M. Katoh;H. Suzuki;M. Matsui

  • Recent advances in the protocols of transgenic mouse mutation assays.

    Takehiko Nohmi;Takayoshi Suzuki;Ken-ichi Masumura

  • Recommendations for the performance of bacterial mutation assays.

    D. Gatehouse;S. Haworth;T. Cebula;E. Gocke

  • Mutagenicity of 30 chemicals in Salmonella typhimurium strains possessing different nitroreductase or O-acetyltransferase activities.

    Pirkko Einistö;Masahiko Watanabe;Jr. Motoi Ishidate;Takehiko Nohmi

  • Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme.

    David A. Eastmond;Andrea Hartwig;Diana Anderson;Wagida A. Anwar

  • A sensitive method for the detection of mutagenic nitroarenes: construction of nitroreductase-overproducing derivatives of Salmonella typhimurium strains TA98 and TA100.

    Masahiko Watanabe;Motoi Ishidate;Takehiko Nohmi

  • The β clamp targets DNA polymerase IV to DNA and strongly increases its processivity

    Jérôme Wagner;Shingo Fujii;Petr Gruz;Takehiko Nohmi

  • Specificity and sensitivity of Salmonella typhimurium YG1041 and YG1042 strains possessing elevated levels of both nitroreductase and acetyltransferase activity

    Yuji Hagiwara;Masahiko Watanabe;Yoshimitsu Oda;Toshio Sofuni

  • Escherichia coli DNA Polymerase IV Mutator Activity: Genetic Requirements and Mutational Specificity

    Jérôme Wagner;Takehiko Nohmi

  • Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair

    Xue Zhang;Katsuyoshi Horibata;Masafumi Saijo;Chie Ishigami

  • Environmental Stress and Lesion-Bypass DNA Polymerases

    Takehiko Nohmi

Frequent Co-Authors

Toshio Sofuni
Toshio Sofuni National Institutes of Health
Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Hiroshi Suzuki
Hiroshi Suzuki Obihiro University of Agriculture and Veterinary Medicine
Fumio Hanaoka
Fumio Hanaoka National Institute of Genetics
Makoto Hayashi
Makoto Hayashi makoto international consulting
Hitoshi Nakagama
Hitoshi Nakagama National Cancer Research Institute, UK
Tetsuya Kamataki
Tetsuya Kamataki Hokkaido University
Takashi Sugimura
Takashi Sugimura National Cancer Centre
Keiji Wakabayashi
Keiji Wakabayashi University of Shizuoka
Chikahide Masutani
Chikahide Masutani Nagoya University

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