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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
15135
World Ranking
1524
National Ranking
47

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award

Overview

Robert P. P. Fuchs is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions to molecular biology and genetics. Among the subfields within their research scope are cancer research, pathology and forensic medicine, as well as cellular and molecular neuroscience.

The scientist's work covers several main topics, prominently featuring DNA repair mechanisms. Additional areas of focus include bacterial genetics and biotechnology, genomics and chromatin dynamics, CRISPR and genetic engineering, DNA and nucleic acid chemistry, cancer therapeutics and mechanisms, and carcinogens and genotoxicity assessment.

They have published extensively on the following topics:

  • DNA Repair Mechanisms
  • Bacterial Genetics and Biotechnology
  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • DNA and Nucleic Acid Chemistry
  • Cancer therapeutics and mechanisms
  • Carcinogens and Genotoxicity Assessment

Frequent co-authors collaborating with Robert P. P. Fuchs include:

  • Shingo Fujii
  • Asako Isogawa
  • João A. Paulo
  • Kazumitsu Onizuka
  • Tatsuro Takahashi

The scientist's recent papers illustrate a focus on DNA repair and related molecular processes:

  • "A Comprehensive View of Translesion Synthesis in Escherichia coli," 2020, Microbiology and Molecular Biology Reviews
  • "Double-strand breaks: When DNA repair events accidentally meet," 2022, DNA repair
  • "Chromatin Pull-Down Methodology Based on DNA Triple Helix Formation," 2020, Methods in molecular biology
  • "Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide," 2021, eLife
  • "Accidental Encounter of Repair Intermediates in Alkylated DNA May Lead to Double-Strand Breaks in Resting Cells," 2024, International Journal of Molecular Sciences

These publications are distributed across various scientific journals, including:

  • Microbiology and Molecular Biology Reviews
  • DNA repair
  • Methods in molecular biology
  • eLife
  • International Journal of Molecular Sciences

Best Publications

  • The Y-Family of DNA Polymerases

    Haruo Ohmori;Errol C. Friedberg;Robert P.P. Fuchs;Myron F. Goodman

  • The dinB Gene Encodes a Novel E. coli DNA Polymerase, DNA Pol IV, Involved in Mutagenesis

    Jérôme Wagner;Petr Gruz;Su-Ryang Kim;Masami Yamada

  • All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis.

    R. Napolitano;R. Janel‐Bintz;J. Wagner;R. P. P. Fuchs

  • Trading places: how do DNA polymerases switch during translesion DNA synthesis?

    Errol C. Friedberg;Alan R. Lehmann;Robert P.P. Fuchs

  • Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

    Samira Fekairi;Sarah Scaglione;Charly Chahwan;Ewan R. Taylor

  • How DNA lesions are turned into mutations within cells

    Vincent Pagès;Robert P P Fuchs

  • Co-localization in replication foci and interaction of human Y-family members, DNA polymerase polη and REVl protein

    Agnès Tissier;Patricia Kannouche;Marie-Pierre Reck;Alan R. Lehmann

  • Chemically modified nucleic acids as immunodetectable probes in hybridization experiments.

    Paul Tchen;Robert P. P. Fuchs;Evelyne Sage;Marc Leng

  • Uncoupling of Leading- and Lagging-Strand DNA Replication During Lesion Bypass in Vivo

    Vincent Pagès;Robert P. Fuchs

  • Physical studies on deoxyribonucleic acid after covalent binding of a carcinogen.

    Robert Fuchs;Michel Daune

  • The β clamp targets DNA polymerase IV to DNA and strongly increases its processivity

    Jérôme Wagner;Shingo Fujii;Petr Gruz;Takehiko Nohmi

  • Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli. Strain specificity and mutation-prone sequences.

    Nicole Koffel-Schwartz;Jean-Michel Verdier;Marc Bichara;Anne-Marie Freund

  • Gaps and forks in DNA replication: Rediscovering old models.

    Alan R. Lehmann;Robert P. Fuchs

  • Molecular analysis of mutations in DNA polymerase η in xeroderma pigmentosum-variant patients

    Bernard C. Broughton;Agnes Cordonnier;Wim J. Kleijer;Nicolaas G. J. Jaspers

  • Hot spots of frameshift mutations induced by the ultimate carcinogen N- acetoxy-N-2-acetylaminofluorene

    Robert P. P. Fuchs;Nicole Schwartz;Michel P. Daune

  • Single adduct mutagenesis: strong effect of the position of a single acetylaminofluorene adduct within a mutation hot spot.

    Dominique Burnouf;Patrice Koehl;Robert P. P. Fuchs

  • DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli: A correlation between the conformation of the premutagenic lesion and the mutation specificity☆

    Marc Bichara;Robert P.P. Fuchs

  • Pivotal role of the β-clamp in translesion DNA synthesis and mutagenesis in E. coli cells

    Olivier J Becherel;Robert P P Fuchs;Jérôme Wagner

  • Defining the position of the switches between replicative and bypass DNA polymerases

    Shingo Fujii;Robert P Fuchs

  • Erratum: Trading places: How do DNA polymerases switch during translesion DNA synthesis? (Molecular Cell (May 27, 2005) 18 (499-505) PII: S1097-2765(05)01276-1 and DOI: 10.1016/j.molcel.2005.03.032)

    Errol C. Friedberg;Alan R. Lehmann;Robert P P Fuchs

Frequent Co-Authors

Alan R. Lehmann
Alan R. Lehmann University of Sussex
Marc Leng
Marc Leng Centre national de la recherche scientifique, CNRS
Takehiko Nohmi
Takehiko Nohmi Gifu University
Errol C. Friedberg
Errol C. Friedberg The University of Texas Southwestern Medical Center
Thomas A. Kunkel
Thomas A. Kunkel National Institutes of Health
Masayuki Takahashi
Masayuki Takahashi Tokyo Institute of Technology
Serge Boiteux
Serge Boiteux Centre national de la recherche scientifique, CNRS
Louise Prakash
Louise Prakash The University of Texas Medical Branch at Galveston
Jacques Laval
Jacques Laval Institut Gustave Roussy
Fumio Hanaoka
Fumio Hanaoka National Institute of Genetics

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