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Chemistry

D-Index
56
Citations
9331
World Ranking
11836
National Ranking
3185

Overview

Suse Broyde is affiliated with New York University in the United States and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Molecular Biology, with additional work in Cancer Research, Materials Chemistry, Genetics, and Infectious Diseases. The scientist has published 41 works in these fields, including 36 publications specifically in Molecular Biology.

The main topics covered in their research include DNA and Nucleic Acid Chemistry, DNA Repair Mechanisms, Advanced Biosensing and Bioanalysis Techniques, Genomics and Chromatin Dynamics, Carcinogens and Genotoxicity Assessment, CRISPR and Genetic Engineering, and Epigenetics and DNA Methylation.

Suse Broyde has frequently published in several scientific venues. Key journals include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 4 publications
  • DNA repair with 3 publications
  • Nucleic Acids Research with 3 publications
  • International Journal of Molecular Sciences with 2 publications
  • Biochemistry with 1 publication

Notable recent papers authored or co-authored by Suse Broyde cover various aspects of DNA repair and molecular mechanisms, including:

  • "Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote DNA exposure for lesion sensing," 2021, DNA repair
  • "Tethering-facilitated DNA 'opening' and complementary roles of β-hairpin motifs in the Rad4/XPC DNA damage sensor protein," 2020, Nucleic Acids Research
  • "Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair," 2022, Nucleic Acids Research
  • "Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex," 2021, DNA repair
  • "Translesion Synthesis Past 5-Formylcytosine-Mediated DNA-Peptide Cross-Links by hPolη Is Dependent on the Local DNA Sequence," 2021, Biochemistry

The scientist collaborates frequently with several fellow researchers. Among the most frequent co-authors are:

  • Hong Mu
  • Nicholas E. Geacintov
  • Iwen Fu
  • Debamita Paul
  • Amirrasoul Tavakoli

Best Publications

  • NMR SOLUTION STRUCTURES OF STEREOISOMERIC COVALENT POLYCYCLIC AROMATIC CARCINOGEN-DNA ADDUCTS : PRINCIPLES, PATTERNS, AND DIVERSITY

    Nicholas E. Geacintov;Monique Cosman;Brian E. Hingerty;Shantu Amin

  • Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.

    Monique Cosman;Carlos de los Santos;Radovan Fiala;Brian E. Hingerty

  • Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer.

    Carlos De Los Santos;Monique Cosman;Brian E. Hingerty;Victor Ibanez

  • Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics.

    Suzanne F. O'Handley;David G. Sanford;Rong Xu;Cathy C. Lester

  • Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

    Monique Cosman;Carlos de los Santos;Radovan Fiala;Brian E. Hingerty

  • Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery.

    Nicholas E. Geacintov;Suse Broyde;Tonko Buterin;Hanspeter Naegeli

  • Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion

    Olga Rechkoblit;Lucy Malinina;Yuan Cheng;Vitaly Kuryavyi

  • NMR and computational characterization of the N-(deoxyguanosin-8-yl)aminofluorene adduct [(AF)G] opposite adenosine in DNA: (AF)G[syn].A[anti] pair formation and its pH dependence.

    David Norman;Perlet Abuaf;Brian E. Hingerty;David Live

  • Nuclear Magnetic Resonance Solution Structures of Covalent Aromatic Amine−DNA Adducts and Their Mutagenic Relevance

    Dinshaw J. Patel;Bing Mao;Zhengtian Gu;Brian E. Hingerty

  • A Water-Mediated and Substrate-Assisted Catalytic Mechanism for Sulfolobus solfataricus DNA Polymerase IV

    Lihua Wang;Xinyun Yu;Po Hu;Suse Broyde

  • The human DNA repair factor XPC‐HR23B distinguishes stereoisomeric benzo[ a ]pyrenyl‐DNA lesions

    Vincent Mocquet;Konstantin Kropachev;Marina Kolbanovskiy;Alexander Kolbanovskiy

  • Polymerase β simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions Per Se

    Linjing Yang;William A. Beard;Samuel H. Wilson;Suse Broyde

  • Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.

    Monique Cosman;Brian E. Hingerty;Natalia Luneva;Shantu Amin

  • Prediction of DNA structure from sequence: a build-up technique.

    Brian E. Hingerty;Samuel Figueroa;Thomas L. Hayden;Suse Broyde

  • NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).d(T-A-C-G-T-A) duplex.

    David Norman;David Live;Mallika Sastry;Roselyn Lipman

  • Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.

    Chin H Lin;Xuanwei Huang;Alexander Kolbanovskii;Brian E Hingerty

  • Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex

    Bing Mao;Brian E. Hingerty;Suse Broyde;Dinshaw J. Patel

  • DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner

    Rebecca A Perlow;Alexander Kolbanovskii;Brian E Hingerty;Nicholas E Geacintov

  • The Chemical Biology of DNA Damage

    Nicholas E. Geacintov;Suse Broyde

  • Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies

    Hong Mu;Konstantin Kropachev;Lihua Wang;Lu Zhang

  • Solution Conformation of the (-)-trans-anti-Benzo[c]phenanthrene-dA ([BPh]dA) Adduct opposite dT in a DNA Duplex: Intercalation of the Covalently Attached Benzo[c]phenanthrenyl Ring to the 3'-Side of the Adduct Site and Comparison with the (+)-trans-anti-[BPh]dA opposite dT Stereoisomer

    Monique Cosman;Alfred Laryea;Radovan Fiala;Brian E. Hingerty

Frequent Co-Authors

Nicholas E. Geacintov
Nicholas E. Geacintov New York University
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Robert Shapiro
Robert Shapiro New York University
Shantu Amin
Shantu Amin Pennsylvania State University
Yingkai Zhang
Yingkai Zhang New York University
Steven D. Stellman
Steven D. Stellman Columbia University
Tamar Schlick
Tamar Schlick New York University
Chuan He
Chuan He University of Chicago
William A. Beard
William A. Beard National Institutes of Health
Samuel H. Wilson
Samuel H. Wilson National Institutes of Health

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