What is she best known for?
The fields of study she is best known for:
Her main research concerns Cell biology, Cancer research, Notch signaling pathway, Signal transduction and Hedgehog.
Her Cell biology study integrates concerns from other disciplines, such as Molecular biology, Transcription factor and T cell, Thymocyte.
Her Cancer research research is multidisciplinary, incorporating perspectives in Carcinogenesis, Cancer, Chromatin immunoprecipitation, RNA interference and Gene silencing.
Isabella Screpanti has researched Notch signaling pathway in several fields, including Interleukin 21, Lymphatic system and Genetically modified mouse.
Her Signal transduction research integrates issues from Tumor progression, Angiogenesis and Alternative splicing.
Many of her research projects under Hedgehog are closely connected to Rex1 with Rex1, tying the diverse disciplines of science together.
Her most cited work include:
- Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice. (380 citations)
- Constitutive activation of NF‐κB and T‐cell leukemia/lymphoma in Notch3 transgenic mice (376 citations)
- Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells (265 citations)
What are the main themes of her work throughout her whole career to date?
The scientist’s investigation covers issues in Cell biology, Cancer research, Signal transduction, Notch signaling pathway and Molecular biology.
The concepts of her Cell biology study are interwoven with issues in Receptor, Cellular differentiation and Immunology.
Her study in Cancer research is interdisciplinary in nature, drawing from both Carcinogenesis, Cancer, T cell, microRNA and Neuroblastoma.
Her work deals with themes such as NUMB, Transcription factor, Neoplastic transformation, HEK 293 cells and T-cell receptor, which intersect with Signal transduction.
Her Molecular biology study incorporates themes from Jurkat cells, Regulation of gene expression and Gene expression, Transcriptional regulation.
Her Hedgehog study combines topics from a wide range of disciplines, such as Medulloblastoma and Hedgehog signaling pathway.
She most often published in these fields:
- Cell biology (54.69%)
- Cancer research (41.41%)
- Signal transduction (29.69%)
What were the highlights of her more recent work (between 2013-2021)?
- Cell biology (54.69%)
- Cancer research (41.41%)
- Notch signaling pathway (21.88%)
In recent papers she was focusing on the following fields of study:
Her primary areas of study are Cell biology, Cancer research, Notch signaling pathway, Signal transduction and Hedgehog.
Particularly relevant to Hedgehog signaling pathway is her body of work in Cell biology.
The various areas that she examines in her Cancer research study include Cancer cell, Cancer, Cancer stem cell, Stem cell and microRNA.
Her Signal transduction study combines topics in areas such as Regulator, Molecular biology and Transcription factor.
She combines subjects such as Medulloblastoma and Crosstalk with her study of Hedgehog.
Her research integrates issues of Sonic hedgehog and Smoothened in her study of GLI1.
Between 2013 and 2021, her most popular works were:
- Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia (106 citations)
- Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia (106 citations)
- Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors (96 citations)
In her most recent research, the most cited papers focused on:
Her primary scientific interests are in Cancer research, Cell biology, Signal transduction, Notch signaling pathway and Hedgehog.
Her Cancer research research includes elements of Histone methyltransferase, Gene knockdown, EZH2, Cell cycle and Gene silencing.
Isabella Screpanti studies Cell biology, focusing on Hedgehog signaling pathway in particular.
Her studies deal with areas such as Molecular biology and Repressor as well as Signal transduction.
The study incorporates disciplines such as Leukemia and Cell signaling in addition to Notch signaling pathway.
Her study in Hedgehog focuses on GLI1 in particular.
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