D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 110 Citations 58,660 304 World Ranking 427 National Ranking 281
Medicine D-index 104 Citations 47,519 240 World Ranking 3063 National Ranking 1762

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary areas of investigation include Notch signaling pathway, Cancer research, Signal transduction, Immunology and Cell biology. His Notch signaling pathway research incorporates themes from Molecular biology, Cell signaling and Transcription factor. His studies in Cancer research integrate themes in fields like Cancer, T cell, Lymphoma, Leukemia and Bone marrow.

His Signal transduction research is multidisciplinary, incorporating perspectives in Cell growth, Extracellular, Protein folding and Chromatin, Chromatin remodeling. His Immunology study combines topics from a wide range of disciplines, such as Mutation, Lineage and Stem cell. His Cell biology research is multidisciplinary, relying on both Genetics and Cellular differentiation.

His most cited work include:

  • Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia (2273 citations)
  • Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning (2088 citations)
  • An immunogenic personal neoantigen vaccine for patients with melanoma (1092 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cancer research, Notch signaling pathway, Cell biology, Immunology and Signal transduction. His Cancer research research is multidisciplinary, incorporating elements of T cell, Leukemia, Bone marrow and Lymphoma. Jon C. Aster has researched Notch signaling pathway in several fields, including Molecular biology and Transcription factor.

His Molecular biology study combines topics in areas such as Reporter gene and Binding site. His Cell biology research integrates issues from Genetics, Transcription and Cellular differentiation. His work in the fields of Immunology, such as Immune system, intersects with other areas such as Population.

He most often published in these fields:

  • Cancer research (41.89%)
  • Notch signaling pathway (33.41%)
  • Cell biology (26.39%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (41.89%)
  • Gene (9.93%)
  • Notch signaling pathway (33.41%)

In recent papers he was focusing on the following fields of study:

Jon C. Aster mainly focuses on Cancer research, Gene, Notch signaling pathway, Cell biology and Myeloid. His Cancer research research includes elements of Malignancy, Phagocytosis, T cell, Lymphoma and Bone marrow. He interconnects Immunohistochemistry, Kinase, Neoplasm and Monoclonal in the investigation of issues within Gene.

Jon C. Aster is investigating Signal transduction and Receptor as part of his examination of Notch signaling pathway. The study incorporates disciplines such as Enhancer, Transcription factor, Transcription and Cellular differentiation in addition to Cell biology. He has included themes like Gastroenterology, Not Otherwise Specified, Pathology and Myeloid leukemia in his Myeloid study.

Between 2018 and 2021, his most popular works were:

  • Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. (215 citations)
  • Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. (215 citations)
  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Jon C. Aster mostly deals with Cancer research, Gene, Antibody, Cell type and Myeloid. Jon C. Aster combines subjects such as T cell, Macrophage, Bone marrow and Combination therapy with his study of Cancer research. His research combines Cell biology and Gene.

His Antibody study incorporates themes from Phagocytosis and Antigen. In his research on the topic of Antigen, Cancer is strongly related with Computational biology. His studies deal with areas such as Arsenic trioxide, Myeloid leukemia, Experimental pathology and DNA Methyltransferase Inhibitor as well as Myeloid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia

Andrew P. Weng;Adolfo A. Ferrando;Woojoong Lee;John P. Morris.
Science (2004)

2922 Citations

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

Margaret A. Shipp;Ken N. Ross;Pablo Tamayo;Andrew P. Weng.
Nature Medicine (2002)

2876 Citations

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

John C Pui;David Allman;Lanwei Xu;Susan DeRocco.
Immunity (1999)

1151 Citations

An immunogenic personal neoantigen vaccine for patients with melanoma

Patrick A. Ott;Zhuting Hu;Derin B. Keskin;Derin B. Keskin;Sachet A. Shukla;Sachet A. Shukla.
Nature (2017)

1054 Citations

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

Annapoorni Rangarajan;Annapoorni Rangarajan;Claudio Talora;Ryuhei Okuyama;Michael Nicolas.
The EMBO Journal (2001)

973 Citations

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma

Kerry J. Savage;Stefano Monti;Jeffery L. Kutok;Giorgio Cattoretti.
Blood (2003)

934 Citations

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

Andrew P. Weng;John M. Millholland;Yumi Yashiro-Ohtani;Marie Laure Arcangeli.
Genes & Development (2006)

917 Citations

Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone Marrow

Warren S. Pear;Juli P. Miller;Lanwei Xu;John C. Pui.
Blood (1998)

904 Citations

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

Teresa Palomero;Wei Keat Lim;Duncan T. Odom;Maria Luisa Sulis.
Proceedings of the National Academy of Sciences of the United States of America (2006)

874 Citations

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

Warren S. Pear;Jon C. Aster;Martin L. Scott;Robert P. Hasserjian.
Journal of Experimental Medicine (1996)

829 Citations

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