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Biology and Biochemistry

D-Index
54
Citations
12924
World Ranking
15486
National Ranking
373

Overview

Gerald de Haan is affiliated with the University Medical Center Groningen in the Netherlands, where their research focuses primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several specific subfields including Molecular Biology, Hematology, Immunology, Physiology, and Genetics.

Their scientific contributions cover a range of main topics such as Epigenetics and DNA Methylation, Hematopoietic Stem Cell Transplantation, Single-cell and Spatial Transcriptomics, Immune cells in cancer, Mesenchymal Stem Cell Research, Immune Cell Function and Interaction, and Cancer-related Gene Regulation.

Gerald de Haan has coauthored extensively with several researchers, frequently collaborating with Arthur Flohr Svendsen, Ellen Weersing, Natalia Skinder, Leonid Bystrykh, and Daozheng Yang.

Their publications appear most often in the venues Experimental Hematology, bioRxiv (Cold Spring Harbor Laboratory), Nature Aging, Nature Communications, and Blood.

Notable recent papers include:

  • A comprehensive transcriptome signature of murine hematopoietic stem cell aging, 2021, Blood
  • Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1, 2021, Nature Communications
  • Targeted methods for epigenetic age predictions in mice, 2020, Scientific Reports
  • Inflammation and Aging of Hematopoietic Stem Cells in Their Niche, 2021, Cells
  • Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response, 2020, Oral Diseases

Best Publications

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • The ageing haematopoietic stem cell compartment

    Hartmut Geiger;Hartmut Geiger;Gerald de Haan;M. Carolina Florian

  • The nature and identification of quantitative trait loci: a community's view.

    Oduola Abiola;Joe M. Angel;Philip Avner;Alexander A. Bachmanov

  • Rescue of salivary gland function after stem cell transplantation in irradiated glands.

    Isabelle M. A. Lombaert;Jeanette F. Brunsting;Pieter K. Wierenga;Hette Faber

  • Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells

    Brad Dykstra;Sandra Olthof;Jaring Schreuder;Martha Ritsema

  • Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.

    Leonid Bystrykh;Ellen Weersing;Bert Dontje;Sue Sutton

  • Mouse Strain-Dependent Changes in Frequency and Proliferation of Hematopoietic Stem Cells During Aging: Correlation Between Lifespan and Cycling Activity

    Gerald de Haan;Gerald de Haan;Willem Nijhof;Willem Nijhof;Gary Van Zant;Gary Van Zant

  • The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

    Leonie M. Kamminga;Leonid V. Bystrykh;Aletta de Boer;Sita Houwer

  • Aging of hematopoietic stem cells

    Gerald de Haan;Seka Simone Lazare

  • Cellular barcoding tool for clonal analysis in the hematopoietic system

    Alice Gerrits;Brad Dykstra;Olga J. Kalmykowa;Karin Klauke

  • Hematopoietic stem cell expansion: challenges and opportunities

    Marta A. Walasek;Ronald van Os;Gerald de Haan

  • Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation

    Karin Klauke;Višnja Radulović;Mathilde Broekhuis;Ellen Weersing

  • Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

    Martti Maimets;Cecilia Rocchi;Reinier Bron;Sarah Pringle

  • Genetical genomics: spotlight on QTL hotspots.

    Rainer Breitling;Yang Li;Bruno M. Tesson;Jingyuan Fu

  • Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands

    Sarah Pringle;Martti Maimets;Marianne van der Zwaag;Monique A. Stokman

  • Intrinsic and Extrinsic Control of Hemopoietic Stem Cell Numbers: Mapping of a Stem Cell Gene

    Gerald de Haan;Gary Van Zant

  • Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding

    Evgenia Verovskaya;Mathilde J. C. Broekhuis;Erik Zwart;Martha Ritsema

  • Purification and ex vivo expansion of fully functional salivary gland stem cells.

    Lalitha S Y Nanduri;Mirjam Baanstra;Hette Faber;Cecilia Rocchi

  • In Vitro Generation of Long-Term Repopulating Hematopoietic Stem Cells by Fibroblast Growth Factor-1

    Gerald de Haan;Ellen Weersing;Bert Dontje;Ronald van Os

  • Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool.

    Isabelle M.A. Lombaert;Jeanette F. Brunsting;Pieter K. Wierenga;Harm H. Kampinga

Frequent Co-Authors

Edo Vellenga
Edo Vellenga University Medical Center Groningen
Hartmut Geiger
Hartmut Geiger University of Ulm
Jan Jacob Schuringa
Jan Jacob Schuringa University Medical Center Groningen
Ritsert C. Jansen
Ritsert C. Jansen University of Groningen
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center
Elissa J. Chesler
Elissa J. Chesler University of Tennessee at Knoxville
Markus Loeffler
Markus Loeffler Leipzig University
Bart J. L. Eggen
Bart J. L. Eggen University Medical Center Groningen
Harm H. Kampinga
Harm H. Kampinga University Medical Center Groningen
Lu Lu
Lu Lu University of Tennessee Health Science Center

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