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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
26869
World Ranking
2579
National Ranking
78

Aled M. Edwards publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Aled M. Edwards sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 2,964 publications — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Aled M. Edwards D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Aled M. Edwards sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 89 D-Index — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His main research concerns Biochemistry, Genetics, Protein structure, Cell biology and Molecular biology. In most of his Biochemistry studies, his work intersects topics such as Biophysics. In general Genetics study, his work on CRISPR, Sequence alignment, DNA repair and Protein subunit often relates to the realm of CRISPR Loci, thereby connecting several areas of interest.

The various areas that he examines in his Protein structure study include Crystallization, Protein crystallization, Genomics, Structural biology and Thermotoga maritima. His studies examine the connections between Cell biology and genetics, as well as such issues in HMG-box, with regards to Origin recognition complex, Replication protein A and SeqA protein domain. His Molecular biology research is multidisciplinary, incorporating elements of Proteome, Structural proteomics, Regulator, Computational biology and Structural genomics.

His most cited work include:

  • Protein production and purification. (655 citations)
  • Architecture of RNA polymerase II and implications for the transcription mechanism. (510 citations)
  • Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. (477 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Crystal structure, Crystallography, Biochemistry, Stereochemistry and Deposition. His Crystal structure research includes themes of Phosphatase, Biophysics, Bromodomain and Cell biology. His work is connected to Protein structure, Structural genomics, Enzyme and Escherichia coli, as a part of Biochemistry.

His research is interdisciplinary, bridging the disciplines of Ligand and Stereochemistry. He merges Deposition with Group in his study. He incorporates Group and FERM domain in his research.

He most often published in these fields:

  • Crystal structure (58.27%)
  • Crystallography (35.56%)
  • Biochemistry (24.49%)

What were the highlights of his more recent work (between 2017-2021)?

  • Crystal structure (58.27%)
  • Crystallography (35.56%)
  • Deposition (11.85%)

In recent papers he was focusing on the following fields of study:

Aled M. Edwards spends much of his time researching Crystal structure, Crystallography, Deposition, Group and Phosphatase. His studies in Crystal structure integrate themes in fields like Stereochemistry, Bromodomain, Peptide and Kinase. Aled M. Edwards studies Bromodomain, focusing on BRD4 in particular.

Aled M. Edwards integrates Crystallography and Domain in his studies. His Group research spans across into fields like FERM domain and Chemical engineering. His Pleckstrin homology domain research focuses on Space and how it relates to Group.

Between 2017 and 2021, his most popular works were:

  • Target 2035: probing the human proteome (38 citations)
  • Donated chemical probes for open science. (31 citations)
  • The RESOLUTE consortium: unlocking SLC transporters for drug discovery. (15 citations)

Best Publications

  • Protein production and purification.

    S Gräslund

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • Architecture of RNA polymerase II and implications for the transcription mechanism.

    Patrick Cramer;David A. Bushnell;Jianhua Fu;Averell L. Gnatt

  • Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.

    Masoud Vedadi;Frank H. Niesen;Abdellah Allali-Hassani;Oleg Y. Fedorov

  • Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA

    Alexey Bochkarev;Richard A. Pfuetzner;Aled M. Edwards;Lori Frappier

  • A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

    Masoud Vedadi;Dalia Barsyte-Lovejoy;Feng Liu;Sylvie Rival-Gervier

  • Hepatic Gene Expression Discriminates Responders and Nonresponders in Treatment of Chronic Hepatitis C Viral Infection

    Limin Chen;Ivan Borozan;Jordan Feld;Jing Sun

  • A Call for Systematic Research on Solute Carriers

    Adrián César-Razquin;Berend Snijder;Tristan Frappier-Brinton;Ruth Isserlin

  • A proposal for validation of antibodies

    Mathias Uhlen;Anita Bandrowski;Steven Carr;Aled Edwards

  • Too many roads not taken

    Aled M Edwards;Ruth Isserlin;Gary D Bader;Stephen V Frye

  • Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.

    Vivian Saridakis;Yi Sheng;Feroz Sarkari;Melissa N. Holowaty

  • Structural proteomics of an archaeon.

    Dinesh Christendat;Adelinda Yee;Akil Dharamsi;Yuval Kluger

  • Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.

    Ekaterina Kuznetsova;Michael Proudfoot;Claudio F. Gonzalez;Greg Brown

  • Bridging structural biology and genomics: assessing protein interaction data with known complexes.

    Aled M Edwards;Bart Kus;Ronald Jansen;Dov Greenbaum

  • The human genome and drug discovery after a decade. Roads (still) not taken

    Ruth Isserlin;Gary D. Bader;Aled Edwards;Stephen Frye

  • A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

    Mohan Babu;Natalia Beloglazova;Robert Flick;Chris Graham

  • Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response

    Karen L. Mossman;Pascale F. Macgregor;Jacob J. Rozmus;Andrew B. Goryachev

  • Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro.

    A M Edwards;C M Kane;R A Young;R D Kornberg

  • Structure and biochemical functions of SIRT6.

    Patricia W. Pan;Jessica L. Feldman;Mark K. Devries;Aiping Dong

  • Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.

    Masoud Vedadi;Jocelyne Lew;Jennifer Artz;Mehrnaz Amani

Frequent Co-Authors

Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Opher Gileadi
Opher Gileadi Karolinska Institute
Udo Oppermann
Udo Oppermann University of Oxford
Panagis Filippakopoulos
Panagis Filippakopoulos Structural Genomics Consortium
Alex N. Bullock
Alex N. Bullock University of Oxford
Oleg Fedorov
Oleg Fedorov University of Oxford
Alexei Savchenko
Alexei Savchenko University of Calgary
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Masoud Vedadi
Masoud Vedadi Structural Genomics Consortium

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