What is he best known for?
The fields of study he is best known for:
Matthieu Schapira mostly deals with Biochemistry, Methyltransferase, Computational biology, Histone and Histone methyltransferase.
His Methyltransferase research is multidisciplinary, incorporating elements of Structure–activity relationship and Transferase.
Matthieu Schapira focuses mostly in the field of Structure–activity relationship, narrowing it down to matters related to DOT1L and, in some cases, Drug discovery and Chemical biology.
His work is dedicated to discovering how Computational biology, Genetics are connected with Binding selectivity and other disciplines.
His Histone research incorporates elements of Multiprotein complex and Active site.
In his research on the topic of Histone methyltransferase, Epigenetics, Epigenomics, Cancer epigenetics, Epigenetic regulation of neurogenesis and Epigenetics in learning and memory is strongly related with Histone methylation.
His most cited work include:
- Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells (2453 citations)
- Epigenetic protein families: a new frontier for drug discovery (956 citations)
- Epigenetic protein families: a new frontier for drug discovery (956 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Biochemistry, Methyltransferase, Computational biology, Histone and Stereochemistry.
His work on Transferase, Small molecule, Binding site and Structure–activity relationship as part of general Biochemistry research is frequently linked to Arginine, bridging the gap between disciplines.
His work deals with themes such as Allosteric regulation, Cofactor, Enzyme and EZH2, which intersect with Methyltransferase.
His Computational biology research is multidisciplinary, incorporating perspectives in Genetics, Protein family, Epigenetics, Structural genomics and Drug discovery.
His research in Histone focuses on subjects like Cell biology, which are connected to Protein domain.
His Histone methyltransferase study also includes fields such as
- Histone H3 together with Molecular biology and Histone methylation,
- Histone H2A which is related to area like Histone code.
He most often published in these fields:
- Biochemistry (50.65%)
- Methyltransferase (44.16%)
- Computational biology (37.23%)
What were the highlights of his more recent work (between 2018-2021)?
- Crystallography (12.12%)
- Computational biology (37.23%)
- X-ray crystallography (7.36%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Crystallography, Computational biology, X-ray crystallography, Methyltransferase and Histone.
His Crystallography study combines topics from a wide range of disciplines, such as Viral replication and Sequence.
His Computational biology research is multidisciplinary, relying on both Druggability, Methylation, Gene, Protein family and Protein degradation.
His Methyltransferase research is within the category of Biochemistry.
His Binding site study in the realm of Biochemistry connects with subjects such as Genetic variability and Severe acute respiratory syndrome coronavirus 2.
His Histone study combines topics in areas such as Chromatin, HEK 293 cells and Cell biology.
Between 2018 and 2021, his most popular works were:
- Targeted protein degradation: expanding the toolbox. (162 citations)
- Targeted protein degradation: expanding the toolbox. (162 citations)
- A chemical biology toolbox to study protein methyltransferases and epigenetic signaling (60 citations)
In his most recent research, the most cited papers focused on:
Matthieu Schapira mainly investigates Computational biology, Methyltransferase, Histone, Chemical biology and Small molecule.
The various areas that Matthieu Schapira examines in his Computational biology study include Ubiquitin, Methylation, Protein degradation, Protein arginine methyltransferase 5 and Protein family.
His Methylation study integrates concerns from other disciplines, such as Structural biology, Jurkat cells, Epigenetics and Cellular differentiation.
Methyltransferase is a subfield of Biochemistry that he tackles.
His Histone study incorporates themes from HEK 293 cells and Genome instability.
His Small molecule research incorporates themes from Chromatin and Tudor domain.
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