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Biology and Biochemistry

D-Index
77
Citations
23078
World Ranking
4745
National Ranking
164

Overview

Susanne Müller is affiliated with the Structural Genomics Consortium in Canada and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their work primarily focuses on molecular biology, oncology, computational theory and mathematics, cell biology, and organic chemistry.

The scientist's research covers several specialized topics, including:

  • Protein Degradation and Inhibitors
  • Ubiquitin and proteasome pathways
  • Computational Drug Discovery Methods
  • Click Chemistry and Applications
  • Cell Adhesion Molecules Research
  • Protein Kinase Regulation and GTPase Signaling
  • Peptidase Inhibition and Analysis

Susanne Müller has published articles in multiple prominent scientific journals. Frequent venues for their publications include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Medicinal Chemistry
  • Nature Communications
  • ACS Chemical Biology
  • RSC Medicinal Chemistry

They have contributed to a number of research papers, with notable recent publications such as:

  • Development of a potent and selective chemical probe for the pleiotropic kinase CK2, 2021, Cell chemical biology
  • The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification, 2021, International Journal of Molecular Sciences
  • Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses, 2023, Cancer Discovery
  • Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2, 2021, Cell chemical biology
  • Target 2035 - update on the quest for a probe for every protein, 2021, RSC Medicinal Chemistry

Collaboration forms a significant part of Susanne Müller's research activities. Frequent co-authors include:

  • Stefan Knapp
  • Benedict-Tilman Berger
  • Thomas Hanke
  • Andreas Krämer
  • Lewis Elson

Best Publications

  • Histone recognition and large-scale structural analysis of the human bromodomain family.

    Panagis Filippakopoulos;Sarah Picaud;Maria Mangos;Tracy Keates

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • Sp1-mediated transcriptional activation is repressed by Sp3.

    G. Hagen;S. Müller;M. Beato;G. Suske

  • HMGB1 is an endogenous immune adjuvant released by necrotic cells

    Patrizia Rovere-Querini;Annalisa Capobianco;Paola Scaffidi;Barbara Valentinis

  • Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

    Gustav Hagen;Susanne Müller;Miguel Beato;Guntram Suske

  • The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells

    Bernard Degryse;Tiziana Bonaldi;Paola Scaffidi;Susanne Müller

  • The double life of HMGB1 chromatin protein: architectural factor and extracellular signal

    Susanne Müller;Paola Scaffidi;Bernard Degryse;Tiziana Bonaldi

  • Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

    Alastair J. Barr;Emilie Ugochukwu;Wen Hwa Lee;Oliver N.F. King

  • Bromodomains as therapeutic targets.

    Susanne Muller;Panagis Filippakopoulos;Stefan Knapp

  • RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.

    Sarah Picaud;Christopher Wells;Ildiko Felletar;Deborah Brotherton

  • Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function

    S. Müller;L. Ronfani;M. E. Bianchi

  • A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

    Oleg Fedorov;Brian Marsden;Vanda Pogacic;Peter Rellos

  • Exogenous High-Mobility Group Box 1 Protein Induces Myocardial Regeneration After Infarction via Enhanced Cardiac C-Kit+ Cell Proliferation and Differentiation

    Federica Limana;Antonia Germani;Antonella Zacheo;Jan Kajstura

  • Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

    Pietro Ciceri;Susanne Müller;Alison O'Mahony;Oleg Fedorov

  • Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.

    Johannes Bange;Dieter Prechtl;Yuri Cheburkin;Katja Specht

  • Comprehensive characterization of the Published Kinase Inhibitor Set

    Jonathan M. Elkins;Vita Fedele;Marta Szklarz;Kamal R. Abdul Azeez

  • The (un)targeted cancer kinome

    Oleg Fedorov;Susanne Müller;Stefan Knapp;Stefan Knapp

  • Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

    Duncan A Hay;Oleg Fedorov;Sarah Martin;Dean C Singleton

  • Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma

    Zhixiang Cheng;Yuanying Gong;Yufang Ma;Kaihua Lu

  • The ins and outs of selective kinase inhibitor development

    Susanne Müller;Apirat Chaikuad;Nathanael S Gray;Stefan Knapp

Frequent Co-Authors

Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Oleg Fedorov
Oleg Fedorov University of Oxford
Paul Brennan
Paul Brennan International Agency For Research On Cancer
Panagis Filippakopoulos
Panagis Filippakopoulos Structural Genomics Consortium
Timothy M. Willson
Timothy M. Willson University of North Carolina at Chapel Hill
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Christopher J. Schofield
Christopher J. Schofield University of Oxford
Opher Gileadi
Opher Gileadi Karolinska Institute
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Marco Bianchi
Marco Bianchi Vita-Salute San Raffaele University

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