His research in Air quality index focuses on subjects like Meteorology, which are connected to Atmosphere (unit). His study looks at the intersection of Variable (mathematics) and topics like Mathematical analysis with Distribution (mathematics). Borrowing concepts from Mathematical analysis, Oleg Fedorov weaves in ideas under Distribution (mathematics). While the research belongs to areas of Table (database), Oleg Fedorov spends his time largely on the problem of Data mining, intersecting his research to questions surrounding Measure (data warehouse). As part of his studies on Measure (data warehouse), Oleg Fedorov often connects relevant subjects like Data mining. The Kinase portion of his research involves studies in Kinome and Protein kinase A. His study in Cryptosporidium parvum extends to Genetics with its themes. Cryptosporidium parvum is frequently linked to Genetics in his study. He merges Computational biology with Biophysics in his study.
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Selective inhibition of BET bromodomains.
Panagis Filippakopoulos;Jun Qi;Sarah Picaud;Yao Shen.
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination.
Masoud Vedadi;Frank H. Niesen;Abdellah Allali-Hassani;Oleg Y. Fedorov.
Proceedings of the National Academy of Sciences of the United States of America (2006)
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases
Oleg Fedorov;Brian Marsden;Vanda Pogacic;Peter Rellos.
Proceedings of the National Academy of Sciences of the United States of America (2007)
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain.
Sarah Picaud;Christopher Wells;Ildiko Felletar;Deborah Brotherton.
Proceedings of the National Academy of Sciences of the United States of America (2013)
The (un)targeted cancer kinome
Oleg Fedorov;Susanne Müller;Stefan Knapp;Stefan Knapp.
Nature Chemical Biology (2010)
Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
Pietro Ciceri;Susanne Müller;Alison O'Mahony;Oleg Fedorov.
Nature Chemical Biology (2014)
Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains
Duncan A Hay;Oleg Fedorov;Sarah Martin;Dean C Singleton.
Journal of the American Chemical Society (2014)
PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains
Sarah Picaud;David Da Costa;Angeliki Thanasopoulou;Panagis Filippakopoulos.
Cancer Research (2013)
3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands.
David S. Hewings;Minghua Wang;Martin Philpott;Oleg Fedorov.
Journal of Medicinal Chemistry (2011)
Structural Analysis Identifies Imidazo[1,2-b]Pyridazines as PIM Kinase Inhibitors with In vitro Antileukemic Activity
Vanda Pogacic;Alex N. Bullock;Oleg Fedorov;Panagis Filippakopoulos.
Cancer Research (2007)
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