Rab K. Prinjha

Overview

Best Publications

• Suppression of inflammation by a synthetic histone mimic

  Edwige Nicodeme;Kate L. Jeffrey;Uwe Schaefer;Soren Beinke

  1729
  Citations

• Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

  Mark A. Dawson;Rab K. Prinjha;Antje Dittmann;George Giotopoulos

  1669
  Citations

• Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

  John P. Cogswell;James Ward;Ian A. Taylor;Michelle Waters

  1089
  Citations

• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

  Huw D Lewis;John Liddle;Jim E Coote;Stephen J Atkinson

  768
  Citations

• Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription

  Minna U. Kaikkonen;Nathanael J. Spann;Sven Heinz;Casey E. Romanoski

  677
  Citations

• Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

  Hao Li;Sally Wetten;Li Li;Pamela L. St. Jean

  595
  Citations

• Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

  Sergio E. Baranzini;Joanne Wang;Rachel A. Gibson;Nicholas Galwey

  591
  Citations

• Neuropilin-2 Is Required In Vivo for Selective Axon Guidance Responses to Secreted Semaphorins

  Roman J. Giger;Jean François Cloutier;Amar Sahay;Rabinder K. Prinjha

  523
  Citations

• BET inhibitor resistance emerges from leukaemia stem cells

  Chun Yew Fong;Omer Gilan;Omer Gilan;Enid Y N Lam;Alan Rubin

  520
  Citations

• An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

  Marian L. Burr;Marian L. Burr;Marian L. Burr;Christina E. Sparbier;Christina E. Sparbier;Kah Lok Chan;Kah Lok Chan;Yih-Chih Chan

  475
  Citations

• Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice

  Ariel Halper-Stromberg;Ching-Lan Lu;Florian Klein;Joshua A. Horwitz

  434
  Citations

• Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation

  Omer Gilan;Omer Gilan;Inmaculada Rioja;Kathy Knezevic;Matthew J. Bell

  402
  Citations

• Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.

  Chun-wa Chung;Hervé Coste;Julia H. White;Olivier Mirguet

  388
  Citations

• Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

  Philip Hayes;Helen J Meadows;Martin J Gunthorpe;Mark H Harries

  386
  Citations

• Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

  Panagiotis Ntziachristos;Panagiotis Ntziachristos;Aristotelis Tsirigos;G. Grant Welstead;Thomas Trimarchi

  373
  Citations

• Suppression of the antiviral response by an influenza histone mimic

  Ivan Marazzi;Jessica S. Y. Ho;Jaehoon Kim;Balaji Manicassamy

  358
  Citations

• Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains

  Olivier Mirguet;Romain Gosmini;Jérôme Toum;Catherine A. Clément

  337
  Citations

• Identification of a Novel Series of Bet Family Bromodomain Inhibitors: Binding Mode and Profile of I-Bet151 (Gsk1210151A).

  Jonathan Seal;Yann Lamotte;Frédéric Donche;Anne Bouillot

  323
  Citations

• Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

  Dan Levy;Alex J Kuo;Yanqi Chang;Uwe Schaefer

  294
  Citations

• Place your BETs: the therapeutic potential of bromodomains

  R.K. Prinjha;J. Witherington;K. Lee

  259
  Citations