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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
26625
World Ranking
8945
National Ranking
685

Overview

Marcus Bantscheff is affiliated with GlaxoSmithKline in the United Kingdom, focusing on research at the intersection of biochemistry, medicine, and chemistry. Their work spans multiple fields and subfields within the life sciences, emphasizing molecular biology and advanced analytical methods.

The main fields of study associated with Bantscheff's research include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Chemistry

More specific subfields within these areas cover:

  • Molecular Biology
  • Spectroscopy
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • Cell Biology

The scientist's research topics are detailed as follows:

  • Advanced Proteomics Techniques and Applications
  • Protein Degradation and Inhibitors
  • Mass Spectrometry Techniques and Applications
  • Ubiquitin and proteasome pathways
  • RNA and protein synthesis mechanisms
  • Computational Drug Discovery Methods
  • Protein Structure and Dynamics

Bantscheff has contributed to scholarly works published in prominent venues, frequently appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Nature Methods
  • Communications Biology
  • Science Advances

Recent publications include:

  • "Mass-spectrometry-based draft of the Arabidopsis proteome," 2020, Nature
  • "Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation," 2020, Science
  • "The emerging role of mass spectrometry-based proteomics in drug discovery," 2022, Nature Reviews Drug Discovery
  • "Meltome atlas-thermal proteome stability across the tree of life," 2020, Nature Methods
  • "Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia," 2021, Nature Cancer

Bantscheff often collaborates with the following coauthors:

  • Thilo Werner
  • H. Christian Eberl
  • Sonja Ghidelli-Disse
  • Nico Zinn
  • Gerard Drewes

Best Publications

  • Quantitative mass spectrometry in proteomics: a critical review

    Marcus Bantscheff;Markus Schirle;Gavain Sweetman;Jens Rick

  • Mass-spectrometry-based draft of the human proteome

    Mathias Wilhelm;Judith Schlegl;Hannes Hahne;Amin Moghaddas Gholami

  • Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

    Mark A. Dawson;Rab K. Prinjha;Antje Dittmann;George Giotopoulos

  • Tracking cancer drugs in living cells by thermal profiling of the proteome

    Mikhail M. Savitski;Friedrich B. M. Reinhard;Holger Franken;Thilo Werner

  • Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

    Marcus Bantscheff;Dirk Eberhard;Yann Abraham;Sonja Bastuck

  • Catalytic in vivo protein knockdown by small-molecule PROTACs

    Daniel P Bondeson;Alina Mares;Ian E D Smith;Eunhwa Ko

  • A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

    Laurens Kruidenier;Chun-wa Chung;Zhongjun Cheng;John Liddle

  • Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present

    Marcus Bantscheff;Simone Lemeer;Mikhail M. Savitski;Bernhard Kuster;Bernhard Kuster

  • Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

    Marcus Bantscheff;Carsten Hopf;Mikhail M Savitski;Antje Dittmann

  • Design of amidobenzimidazole STING receptor agonists with systemic activity

    J.M. Ramanjulu;G.S. Pesiridis;J. Yang;N. Concha

  • Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

    Holger Franken;Toby Mathieson;Dorothee Childs;Gavain M A Sweetman

  • Mass-spectrometry-based draft of the Arabidopsis proteome.

    Julia Mergner;Martin Frejno;Markus List;Michael Papacek

  • Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

    J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  • A scalable approach for protein false discovery rate estimation in large proteomic data sets

    Mikhail M. Savitski;Mathias Wilhelm;Hannes Hahne;Bernhard Kuster;Bernhard Kuster

  • Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation

    Omer Gilan;Omer Gilan;Inmaculada Rioja;Kathy Knezevic;Matthew J. Bell

  • Systematic analysis of protein turnover in primary cells

    Toby Mathieson;Holger Franken;Jan Kosinski;Nils Kurzawa

  • Confident Phosphorylation Site Localization Using the Mascot Delta Score

    Mikhail M. Savitski;Simone Lemeer;Markus Boesche;Manja Lang

  • Measuring and managing ratio compression for accurate iTRAQ/TMT quantification.

    Mikhail M. Savitski;Toby Mathieson;Nico Zinn;Gavain Sweetman

  • Ion coalescence of neutron encoded TMT 10-plex reporter ions.

    Thilo Werner;Gavain Sweetman;Maria Fälth Savitski;Toby Mathieson

  • Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

    Friedrich B M Reinhard;Dirk Eberhard;Thilo Werner;Holger Franken

Frequent Co-Authors

Gerard Drewes
Gerard Drewes GlaxoSmithKline (United Kingdom)
Mikhail M. Savitski
Mikhail M. Savitski European Bioinformatics Institute
Bernhard Kuster
Bernhard Kuster Technical University of Munich
Wolfgang Huber
Wolfgang Huber European Bioinformatics Institute
Rab K. Prinjha
Rab K. Prinjha GlaxoSmithKline (United Kingdom)
Chun-wa Chung
Chun-wa Chung GlaxoSmithKline (United Kingdom)
Mark A. Dawson
Mark A. Dawson Peter MacCallum Cancer Centre
Udo Oppermann
Udo Oppermann University of Oxford
Markus Schirle
Markus Schirle Novartis (Switzerland)
Michael J. Blackman
Michael J. Blackman London School of Hygiene & Tropical Medicine

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