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Biology and Biochemistry

D-Index
63
Citations
21111
World Ranking
10004
National Ranking
766

Overview

Mikhail M. Savitski is affiliated with the European Bioinformatics Institute in the United Kingdom. Their research activity focuses on Biochemistry, Genetics, and Molecular Biology, with an emphasis on Molecular Biology, Spectroscopy, Genetics, Ecology, and Cell Biology as key subfields.

The scientist's work covers several main topics including Advanced Proteomics Techniques and Applications, Mass Spectrometry Techniques and Applications, Bacteriophages and microbial interactions, Protein Structure and Dynamics, RNA and protein synthesis mechanisms, Bacterial Genetics and Biotechnology, and RNA Research and Splicing.

Frequent collaborators in their research include Athanasios Typas, Isabelle Becher, André Mateus, Frank Stein, and Clément M. Potel.

Mikhail M. Savitski's recent publications illustrate a range of scientific contributions:

  • Control of protein stability by post-translational modifications, 2023, Nature Communications
  • A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance, 2020, Cell
  • Bioaccumulation of therapeutic drugs by human gut bacteria, 2021, Nature
  • Meltome atlas-thermal proteome stability across the tree of life, 2020, Nature Methods
  • Thermal proteome profiling for interrogating protein interactions, 2020, Molecular Systems Biology

The most common venues where Mikhail M. Savitski publishes include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Molecular Systems Biology, Zenodo (CERN European Organization for Nuclear Research), and Cell.

Best Publications

  • Mass-spectrometry-based draft of the human proteome

    Mathias Wilhelm;Judith Schlegl;Hannes Hahne;Amin Moghaddas Gholami

  • Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

    Mark A. Dawson;Rab K. Prinjha;Antje Dittmann;George Giotopoulos

  • Tracking cancer drugs in living cells by thermal profiling of the proteome

    Mikhail M. Savitski;Friedrich B. M. Reinhard;Holger Franken;Thilo Werner

  • Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present

    Marcus Bantscheff;Simone Lemeer;Mikhail M. Savitski;Bernhard Kuster;Bernhard Kuster

  • Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

    Marcus Bantscheff;Carsten Hopf;Mikhail M Savitski;Antje Dittmann

  • A new antibiotic selectively kills Gram-negative pathogens

    Yu Imai;Kirsten J. Meyer;Akira Iinishi;Quentin Favre-Godal

  • Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

    Holger Franken;Toby Mathieson;Dorothee Childs;Gavain M A Sweetman

  • The functional landscape of the human phosphoproteome

    David Ochoa;Andrew F. Jarnuczak;Cristina Viéitez;Maja Gehre

  • A scalable approach for protein false discovery rate estimation in large proteomic data sets

    Mikhail M. Savitski;Mathias Wilhelm;Hannes Hahne;Bernhard Kuster;Bernhard Kuster

  • Species-specific activity of antibacterial drug combinations

    Ana Rita Brochado;Anja Telzerow;Jacob Bobonis;Manuel Banzhaf

  • Systematic analysis of protein turnover in primary cells

    Toby Mathieson;Holger Franken;Jan Kosinski;Nils Kurzawa

  • Confident Phosphorylation Site Localization Using the Mascot Delta Score

    Mikhail M. Savitski;Simone Lemeer;Markus Boesche;Manja Lang

  • Measuring and managing ratio compression for accurate iTRAQ/TMT quantification.

    Mikhail M. Savitski;Toby Mathieson;Nico Zinn;Gavain Sweetman

  • Ion coalescence of neutron encoded TMT 10-plex reporter ions.

    Thilo Werner;Gavain Sweetman;Maria Fälth Savitski;Toby Mathieson

  • Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

    Friedrich B M Reinhard;Dirk Eberhard;Thilo Werner;Holger Franken

  • A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance.

    James K. Martin;Joseph P. Sheehan;Benjamin P. Bratton;Gabriel M. Moore

  • De novo peptide sequencing and identification with precision mass spectrometry.

    Ari M. Frank;Mikhail M. Savitski;Michael N. Nielsen;Roman A. Zubarev

  • Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.

    Isabelle Becher;Thilo Werner;Carola Doce;Esther A Zaal

  • Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

    Sindhuja Sridharan;Nils Kurzawa;Thilo Werner;Ina Günthner

  • High-Resolution Enabled TMT 8-plexing

    Thilo Werner;Isabelle Becher;Gavain Sweetman;Carola Doce

Frequent Co-Authors

Marcus Bantscheff
Marcus Bantscheff GlaxoSmithKline (United Kingdom)
Roman A. Zubarev
Roman A. Zubarev Karolinska Institute
Athanasios Typas
Athanasios Typas Molecular Medicine Partnership Unit
Michael L. Nielsen
Michael L. Nielsen University of Copenhagen
Bernhard Kuster
Bernhard Kuster Technical University of Munich
Gerard Drewes
Gerard Drewes GlaxoSmithKline (United Kingdom)
Wolfgang Huber
Wolfgang Huber European Bioinformatics Institute
Pedro Beltrao
Pedro Beltrao European Bioinformatics Institute
Rab K. Prinjha
Rab K. Prinjha GlaxoSmithKline (United Kingdom)
Vladimir Benes
Vladimir Benes European Molecular Biology Laboratory

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