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Ruedi Aebersold

Ruedi Aebersold

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Best Scientists
2025
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Biology and Biochemistry
Switzerland
2026

D-Index & Metrics

Best Scientists

D-Index
220
Citations
208038
World Ranking
140
National Ranking
2

Biology and Biochemistry

D-Index
224
Citations
215883
World Ranking
17
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2014 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ruedi Aebersold is affiliated with ETH Zurich in Switzerland and is active in the fields of Biochemistry, Genetics and Molecular Biology. Their research output includes notable contributions across molecular biology, spectroscopy, cancer research, oncology, and cell biology.

The primary research topics covered by this scientist include:

  • Advanced Proteomics Techniques and Applications
  • Bioinformatics and Genomic Networks
  • Metabolomics and Mass Spectrometry Studies
  • Mass Spectrometry Techniques and Applications
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Microbial Metabolic Engineering and Bioproduction

Selected recent papers authored by Ruedi Aebersold include:

  • "diaPASEF: parallel accumulation-serial fragmentation combined with data-independent acquisition," 2020, Nature Methods
  • "Proteomic and interactomic insights into the molecular basis of cell functional diversity," 2020, Nature Reviews Molecular Cell Biology
  • "JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications," 2021, Science
  • "A high-stringency blueprint of the human proteome," 2020, Nature Communications
  • "ChromID identifies the protein interactome at chromatin marks," 2020, Nature Biotechnology

The frequent co-authors collaborating with this scientist are:

  • Tiannan Guo
  • Ben C. Collins
  • Anthony W. Purcell
  • Yu-Ju Chen
  • Henning Hermjakob

Ruedi Aebersold's work has been published extensively in several venues, particularly:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PROTEOMICS
  • Nature Communications
  • Journal of Proteome Research
  • Molecular Systems Biology

The scientist has received recognition including membership in the European Molecular Biology Organization (EMBO) and election to the German National Academy of Sciences Leopoldina in 2014 for contributions in Biochemistry and Biophysics.

Best Publications

  • Mass spectrometry-based proteomics

    Ruedi Aebersold;Matthias Mann

  • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

    Steven P. Gygi;Beate Rist;Scott A. Gerber;Frantisek Turecek

  • Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search.

    Andrew Keller;Alexey I. Nesvizhskii;Eugene Kolker;Ruedi Aebersold

  • A statistical model for identifying proteins by tandem mass spectrometry.

    Alexey I. Nesvizhskii;Andrew Keller;Eugene Kolker;Ruedi Aebersold

  • Molecular characterization of mitochondrial apoptosis-inducing factor

    Santos A. Susin;Hans K. Lorenzo;Naoufal Zamzami;Isabel Marzo

  • Correlation between Protein and mRNA Abundance in Yeast

    Steven P. Gygi;Yvan Rochon;B. Robert Franza;Ruedi Aebersold

  • Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis

    Ludovic C. Gillet;Pedro Navarro;Stephen Tate;Hannes Röst

  • On the Dependency of Cellular Protein Levels on mRNA Abundance.

    Yansheng Liu;Andreas Beyer;Ruedi Aebersold;Ruedi Aebersold

  • Mass spectrometry and protein analysis.

    Bruno Domon;Ruedi Aebersold;Ruedi Aebersold

  • Integrated genomic and proteomic analyses of a systematically perturbed metabolic network.

    Trey Ideker;Vesteinn Thorsson;Jeffrey A. Ranish;Rowan Christmas

  • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

    Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron

  • A cellular gene encodes scrapie PrP 27-30 protein

    Bruno Oesch;Bruno Oesch;David Westaway;Monika Wälchli;Monika Wälchli;Michael P. McKinley

  • Mass-spectrometric exploration of proteome structure and function

    Ruedi Aebersold;Ruedi Aebersold;Matthias Mann

  • Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology

    Steven P. Gygi;Garry L. Corthals;Yanni Zhang;Yvan Rochon

  • The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

    Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert

  • Mass Spectrometry in Proteomics

    Ruedi Aebersold;David R. Goodlett

  • SELECTED REACTION MONITORING FOR QUANTITATIVE PROTEOMICS: A TUTORIAL

    Vinzenz Lange;Paola Picotti;Bruno Domon;Ruedi Aebersold

  • Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

    Hui Zhang;Xiao jun Li;Daniel B. Martin;Ruedi Aebersold

  • Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

    Anne-Claude Gingras;Steven P. Gygi;Brian Raught;Roberto D. Polakiewicz

  • Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions

    Paola Picotti;Ruedi Aebersold;Ruedi Aebersold

Frequent Co-Authors

Eric W. Deutsch
Eric W. Deutsch University of Washington
Jimmy K. Eng
Jimmy K. Eng University of Washington
David R. Goodlett
David R. Goodlett University of Victoria
Alexey I. Nesvizhskii
Alexey I. Nesvizhskii University of Michigan–Ann Arbor
Eugene C. Yi
Eugene C. Yi Seoul National University
Alexander Schmidt
Alexander Schmidt University of Basel
Robert L. Moritz
Robert L. Moritz Institute for Systems Biology
Paola Picotti
Paola Picotti ETH Zurich

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