H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry H-index 186 Citations 118,066 608 World Ranking 20 National Ranking 17

Research.com Recognitions

Awards & Achievements

2009 - US President's National Medal of Science "For his discovery of prions, the causative agent of bovine spongiform encephalopathy and other related neurodegenerative diseases, and his continuing efforts to develop effective methods for detecting and treating prion diseases. ", Presented by President Barack H. Obama in the East Room of the White House on November 17, 2010.

1998 - Benjamin Franklin Medal, Franklin Institute

1997 - Fellow of the American Association for the Advancement of Science (AAAS)

1997 - Fellow of the Royal Society, United Kingdom

1997 - Louisa Gross Horwitz Prize, Columbia University

1997 - Nobel Prize for his discovery of Prions - a new biological principle of infection

1996 - Keio Medical Science Prize, Keio University, Tokyo, Japan

1995 - Paul Ehrlich and Ludwig Darmstaedter Prize

1995 - Robert J. and Claire Pasarow Foundation Medical Research Award

1994 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

1993 - Canada Gairdner International Award

1993 - Fellow of the American Academy of Arts and Sciences

1992 - Member of the National Academy of Medicine (NAM)

1992 - Member of the National Academy of Sciences

1991 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

1991 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology

1991 - Sedgwick Memorial Medal, American Public Health Association

1976 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Scrapie, Virology, Molecular biology, Biochemistry and PrPSc Proteins. The Scrapie study combines topics in areas such as Transgene, Proteinase K, Hamster and Gene isoform. His Virology research includes themes of Pathogenesis, Bovine spongiform encephalopathy, Neurodegeneration, Disease and Genetically modified mouse.

His Molecular biology study combines topics from a wide range of disciplines, such as Complementary DNA, Messenger RNA, Gene, Blot and Epitope. Biochemistry and Amyloid are commonly linked in his work. His work carried out in the field of PrPSc Proteins brings together such families of science as Cell culture, Cell, Phospholipase C, Transmissible mink encephalopathy and Cell biology.

His most cited work include:

  • Nobel Lecture: Prions (4075 citations)
  • Novel proteinaceous infectious particles cause scrapie (4009 citations)
  • Molecular biology of prion diseases (1717 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Scrapie, Virology, Biochemistry, Molecular biology and Gene isoform. His work is dedicated to discovering how Scrapie, Infectivity are connected with Nucleic acid and other disciplines. His Virology research includes elements of Genetically modified mouse, Gene, Transgene, Bovine spongiform encephalopathy and Disease.

His study connects Prion protein and Biochemistry. His work carried out in the field of Molecular biology brings together such families of science as Amino acid, Recombinant DNA, Proteinase K and Epitope, Antibody. His PrPSc Proteins study typically links adjacent topics like Cell culture.

He most often published in these fields:

  • Scrapie (41.07%)
  • Virology (34.96%)
  • Biochemistry (25.97%)

What were the highlights of his more recent work (between 2006-2021)?

  • Virology (34.96%)
  • Biochemistry (25.97%)
  • Genetically modified mouse (11.11%)

In recent papers he was focusing on the following fields of study:

His main research concerns Virology, Biochemistry, Genetically modified mouse, Molecular biology and Scrapie. His biological study spans a wide range of topics, including Cell culture, PrPSc Proteins, Neurodegeneration, Chronic wasting disease and Gene isoform. Stanley B. Prusiner has included themes like Infectivity, Prion protein and Amyloid in his Biochemistry study.

His Genetically modified mouse research is multidisciplinary, incorporating perspectives in Phenotype, Bovine spongiform encephalopathy, Neuroscience and Alpha-synuclein. His Molecular biology study combines topics from a wide range of disciplines, such as Monoclonal antibody, In vivo and PRNP. His Scrapie research is multidisciplinary, relying on both Pathogen, Microbiology, Proteinase K and Incubation.

Between 2006 and 2021, his most popular works were:

  • Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism (377 citations)
  • A Unifying Role for Prions in Neurodegenerative Diseases (362 citations)
  • Biology and genetics of prions causing neurodegeneration. (294 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Stanley B. Prusiner spends much of his time researching Virology, Biochemistry, Molecular biology, Amyloid and Genetically modified mouse. His research integrates issues of Scrapie, Chronic wasting disease, Alpha-synuclein, Neurodegeneration and Gene isoform in his study of Virology. The Scrapie study combines topics in areas such as Transport protein and Endosome.

In his work, Drug resistance is strongly intertwined with Cell culture, which is a subfield of Biochemistry. His Molecular biology study incorporates themes from In vitro, Transgene, Prion infectivity, Neural crest and Bank vole. His Amyloid study integrates concerns from other disciplines, such as Fungal protein, Saccharomyces cerevisiae and Recombinant DNA.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Novel proteinaceous infectious particles cause scrapie

Stanley B. Prusiner.
Science (1982)

7066 Citations

Nobel Lecture: Prions

S. B. Prusiner.
Proceedings of the National Academy of Sciences of the United States of America (1998)

6977 Citations

Molecular biology of prion diseases

Stanley B. Prusiner.
Science (1991)

2790 Citations

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

Hansruedi Büeler;Marek Fischer;Yolande Lang;Yolande Lang;Horst Bluethmann;Horst Bluethmann.
Nature (1992)

2012 Citations

A cellular gene encodes scrapie PrP 27-30 protein

Bruno Oesch;Bruno Oesch;David Westaway;Monika Wälchli;Monika Wälchli;Michael P. McKinley.
Cell (1985)

1903 Citations

Identification of a protein that purifies with the scrapie prion.

David C. Bolton;Michael P. McKinley;Stanley B. Prusiner.
Science (1982)

1743 Citations

Scrapie prion protein contains a phosphatidylinositol glycolipid

Neil Stahl;David R. Borchelt;Karen Hsiao;Stanley B. Prusiner.
Cell (1987)

1482 Citations

Scrapie prions aggregate to form amyloid-like birefringent rods

Stanley B. Prusiner;Michael P. McKinley;Karen A. Bowman;David C. Bolton.
Cell (1983)

1430 Citations

Eight prion strains have PrP Sc molecules with different conformations

Jiri Safar;Holger Wille;Vincenza Itri;Darlene Groth.
Nature Medicine (1998)

1419 Citations

Prion Diseases and the BSE Crisis

Stanley B. Prusiner.
Science (1997)

1263 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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