George A. Carlson

Overview

Best Publications

• Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

  Martin Citron;David Westaway;Weiming Xia;George Carlson

  1800
  Citations

• Propagation of Tau Pathology in a Model of Early Alzheimer’s Disease

  Alix de Calignon;Manuela Polydoro;Marc Suárez-Calvet;Marc Suárez-Calvet;Christopher William

  1595
  Citations

• Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

  M. Azhar Chishti;Dun-Shen Yang;Christopher Janus;Amie L. Phinney

  1186
  Citations

• Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

  Stanley B. Prusiner;Michael Scott;Dallas Foster;Keh-Ming Pan

  1128
  Citations

• Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

  Brian R. Hoover;Miranda N. Reed;Jianjun Su;Rachel D. Penrod

  1092
  Citations

• Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques

  Michael Scott;Dallas Foster;Carol Mirenda;Dan Serban

  939
  Citations

• The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

  Marcus A. Westerman;Deirdre Cooper-Blacketer;Ami Mariash;Linda Kotilinek

  900
  Citations

• Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)

  Martin Ramsden;Linda Kotilinek;Colleen Forster;Jennifer Paulson

  735
  Citations

• Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.

  R. C. Moore;I. Y. Lee;G. L. Silverman;P. M. Harrison

  700
  Citations

• Age-Related CNS Disorder and Early Death in Transgenic FVB/N Mice Overexpressing Alzheimer Amyloid Precursor Proteins

  Karen K. Hsiao;David R. Borchelt;Kristine Olson;Rosa Johannsdottir

  663
  Citations

• Caspase activation precedes and leads to tangles

  Alix de Calignon;Leora M. Fox;Rose Pitstick;George A. Carlson

  640
  Citations

• Distinct prion proteins in short and long scrapie incubation period mice

  David Westaway;Patricia A. Goodman;Carol A. Mirenda;Michael P. McKinley

  616
  Citations

• Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains.

  Paul Markel;Pei Shu;Chris Ebeling;George A. Carlson

  497
  Citations

• Linkage of prion protein and scrapie incubation time genes

  George A. Carlson;David T. Kingsbury;Patricia A. Goodman;Sherrie Coleman

  493
  Citations

• SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein.

  Costantino Iadecola;Fangyi Zhang;Kiyoshi Niwa;Chris Eckman

  482
  Citations

• Identification and Characterization of the Mouse Obesity Gene tubby: A Member of a Novel Gene Family

  Patrick W Kleyn;Wei Fan;Steve G Kovats;John J Lee

  470
  Citations

• Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.

  Tara L. Spires;Jennifer D. Orne;Karen SantaCruz;Rose Pitstick

  454
  Citations

• Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo

  Marc Aurel Busche;Susanne Wegmann;Susanne Wegmann;Simon Dujardin;Caitlin Commins

  441
  Citations

• Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins.

  David Westaway;Stephen J. DeArmond;Juliana Cayetano-Canlas;Darlene Groth

  418
  Citations

• Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein.

  Laibaik Park;Ping Zhou;Rose Pitstick;Carmen Capone

  357
  Citations