D-Index & Metrics Best Publications
Biology and Biochemistry
UK
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 114 Citations 63,461 535 World Ranking 2676 National Ranking 276
Biology and Biochemistry D-index 117 Citations 65,959 543 World Ranking 485 National Ranking 27

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award

2005 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • DNA

Virology, Scrapie, Bovine spongiform encephalopathy, Genetics and PrPSc Proteins are his primary areas of study. His Virology research incorporates themes from Phenotype, Genetically modified mouse, Gene and Transgene. The Scrapie study combines topics in areas such as Spleen, Immunology, Hamster and Cell biology.

John Collinge has included themes like Creutzfeldt-Jakob Syndrome, Kuru, Genotype and Fatal familial insomnia in his Bovine spongiform encephalopathy study. His Genetics research focuses on subjects like Dementia, which are linked to Amyotrophic lateral sclerosis. His PrPSc Proteins research is multidisciplinary, relying on both Transmissible spongiform encephalopathy and In vitro.

His most cited work include:

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2614 citations)
  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (2556 citations)
  • TREM2 Variants in Alzheimer's Disease (1646 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Disease, Virology, Genetics, Scrapie and PRNP. His Disease research is multidisciplinary, incorporating elements of Transmission and Immunology. His work carried out in the field of Virology brings together such families of science as Creutzfeldt-Jakob Syndrome, Bovine spongiform encephalopathy, Prion protein, Fatal familial insomnia and PrPSc Proteins.

John Collinge has researched Bovine spongiform encephalopathy in several fields, including Transmissible spongiform encephalopathy, Genetically modified mouse and Kuru. His research is interdisciplinary, bridging the disciplines of Alzheimer's disease and Genetics. The concepts of his Scrapie study are interwoven with issues in In vitro, Incubation period and Antibody, Monoclonal antibody.

He most often published in these fields:

  • Disease (35.02%)
  • Virology (33.66%)
  • Genetics (26.46%)

What were the highlights of his more recent work (between 2015-2021)?

  • Disease (35.02%)
  • PRNP (18.48%)
  • Genetics (26.46%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Disease, PRNP, Genetics, Internal medicine and Prion protein. His Disease study is related to the wider topic of Pathology. John Collinge usually deals with PRNP and limits it to topics linked to Kuru and Bovine spongiform encephalopathy.

Much of his study explores Genetics relationship to Family history. His studies in Prion protein integrate themes in fields like Biophysics and Virology. His Virology study integrates concerns from other disciplines, such as Genetically modified mouse, Variant cjd and Amyloid.

Between 2015 and 2021, his most popular works were:

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (429 citations)
  • Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes (275 citations)
  • Mammalian prions and their wider relevance in neurodegenerative diseases (114 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • DNA

His primary scientific interests are in Disease, Neurodegeneration, Cell biology, Neurology and Creutzfeldt-Jakob Syndrome. His Disease research includes elements of Genome-wide association study and Bioinformatics. His Bovine spongiform encephalopathy study combines topics in areas such as Scrapie, Chronic wasting disease, Kuru, Cellular protein and Mutation.

His studies deal with areas such as Neurotoxicity, Neuroscience and Virology as well as Cellular protein. His Virology research integrates issues from Cell culture and Prion infectivity. His PRNP research is included under the broader classification of Genetics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj.
Nature Genetics (2013)

3630 Citations

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims.
Nature Genetics (2009)

2992 Citations

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

D Harold;R Abraham;P Hollingworth;R Sims.
Nature Genetics (2013)

2857 Citations

TREM2 Variants in Alzheimer's Disease

Rita Guerreiro;Rita Guerreiro;Aleksandra Wojtas;Jose Bras;Minerva Carrasquillo.
The New England Journal of Medicine (2013)

2446 Citations

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD

John Collinge;John Collinge;Katie C. L. Sidle;Julie Meads;James Ironside.
Nature (1996)

2260 Citations

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish.
Nature Genetics (2011)

1904 Citations

The same prion strain causes vCJD and BSE

Andrew F. Hill;Melanie Desbruslais;Susan Joiner;Katie C. L. Sidle.
Nature (1997)

1805 Citations

Prion Diseases of Humans and Animals: Their Causes and Molecular Basis

John Collinge.
Annual Review of Neuroscience (2001)

1768 Citations

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi.
PLOS ONE (2014)

1380 Citations

A General Model of Prion Strains and Their Pathogenicity

John Collinge;Anthony R. Clarke.
Science (2007)

1303 Citations

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