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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
127
Citations
80624
World Ranking
460
National Ranking
25

Medicine

D-Index
128
Citations
81149
World Ranking
2656
National Ranking
275

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2005 - Fellow of the Royal Society, United Kingdom

Overview

John Collinge is affiliated with University College London in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in the fields of medicine and molecular biology. Within these fields, Collinge has explored subfields such as molecular biology, neurology, physiology, nutrition and dietetics, and ecology.

The scientist's research addresses a range of topics, including:

  • Prion diseases and protein misfolding
  • Neurological diseases and metabolism
  • Alzheimer's disease research and treatments
  • Trace elements in health
  • RNA regulation and disease
  • Amyotrophic lateral sclerosis research
  • RNA research and splicing

Collinge has published extensively in various venues. The most frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Brain
  • Journal of Molecular Biology
  • Journal of Neurology Neurosurgery & Psychiatry

Recent papers authored or co-authored by Collinge include:

  • 2.7 Å cryo-EM structure of ex vivo RML prion fibrils, 2022, Nature Communications
  • Iatrogenic cerebral amyloid angiopathy: an emerging clinical phenomenon, 2022, Journal of Neurology Neurosurgery & Psychiatry
  • Iatrogenic Alzheimer's disease in recipients of cadaveric pituitary-derived growth hormone, 2024, Nature Medicine
  • A structural basis for prion strain diversity, 2023, Nature Chemical Biology
  • Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study, 2020, The Lancet Neurology

Frequent collaborators include Simon Mead, Akın Nihat, Sebastian Brandner, Peter Rudge, and Tracy Campbell, reflecting ongoing partnerships in their research endeavors.

John Collinge was named Fellow of the Royal Society, United Kingdom in 2005, recognizing contributions to their field.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • TREM2 Variants in Alzheimer's Disease

    Rita Guerreiro;Rita Guerreiro;Aleksandra Wojtas;Jose Bras;Minerva Carrasquillo

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD

    John Collinge;John Collinge;Katie C. L. Sidle;Julie Meads;James Ironside

  • The same prion strain causes vCJD and BSE

    Andrew F. Hill;Melanie Desbruslais;Susan Joiner;Katie C. L. Sidle

  • Prion Diseases of Humans and Animals: Their Causes and Molecular Basis

    John Collinge

  • A General Model of Prion Strains and Their Pathogenicity

    John Collinge;Anthony R. Clarke

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • HOMOZYGOUS PRION PROTEIN GENOTYPE PREDISPOSES TO SPORADIC CREUTZFELDT-JAKOB DISEASE

    M S Palmer;A J Dryden;J T Hughes;J Collinge

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Prion protein is necessary for normal synaptic function

    John Collinge;Miles A. Whittington;Katie C. L. Sidle;Corinne J. Smith

  • Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

    Gaia Skibinski;Nicholas J Parkinson;Jeremy M Brown;Lisa Chakrabarti;Lisa Chakrabarti

  • Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples

    AF Hill;RJ Butterworth;S Joiner;G Jackson

  • Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay.

    J.D.F. Wadsworth;S. Joiner;A.F. Hill;T.A. Campbell

  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Lesley Jones;Peter A. Holmans;Marian L. Hamshere;Denise Harold

  • Depleting Neuronal PrP in Prion Infection Prevents Disease and Reverses Spongiosis

    Giovanna Mallucci;Andrew Dickinson;Jacqueline Linehan;Peter-Christian Klöhn

  • Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease.

    J. Collinge;M.S. Palmer;A.J. Dryden

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

Frequent Co-Authors

Simon Mead
Simon Mead University College London Hospitals NHS Foundation Trust
Sebastian Brandner
Sebastian Brandner University College London
Martin N. Rossor
Martin N. Rossor University College London
Nick C. Fox
Nick C. Fox University College London
Andrew F. Hill
Andrew F. Hill Victoria University
John Hardy
John Hardy University College London
Elizabeth M. C. Fisher
Elizabeth M. C. Fisher University College London
Jonathan D. Rohrer
Jonathan D. Rohrer University College London
Michael P. Alpers
Michael P. Alpers Curtin University
Jason D. Warren
Jason D. Warren University College London

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