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Biology and Biochemistry

D-Index
67
Citations
32387
World Ranking
8037
National Ranking
58

Overview

Matti Pirinen is affiliated with the University of Helsinki in Finland and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research output spans a broad range of topics with a particular focus on genetics, molecular biology, and related medical applications.

Within their main fields of study, Matti Pirinen has predominantly worked on:

  • Medicine (127 publications)
  • Biochemistry, Genetics and Molecular Biology (109 publications)

More specifically, their work includes contributions to the following subfields:

  • Genetics (79 publications)
  • Molecular Biology (21 publications)
  • Psychiatry and Mental health (17 publications)
  • Surgery (15 publications)
  • Immunology (9 publications)

The main research topics covered by their publications include:

  • Genetic Associations and Epidemiology (72 publications)
  • Migraine and Headache Studies (22 publications)
  • Genetic Mapping and Diversity in Plants and Animals (16 publications)
  • Bioinformatics and Genomic Networks (14 publications)
  • Neuroscience of respiration and sleep (14 publications)
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (14 publications)
  • Birth, Development, and Health (14 publications)

Matti Pirinen has published research in several scholarly venues, predominantly in the following journals and platforms:

  • bioRxiv (Cold Spring Harbor Laboratory), 26 publications
  • Nature Genetics, 4 publications
  • Nature Communications, 4 publications
  • Nature, 4 publications
  • Atherosclerosis, 4 publications

Some recent papers authored or coauthored by Matti Pirinen include:

  • "Functionally informed fine-mapping and polygenic localization of complex trait heritability" (2020, Nature Genetics)
  • "Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles" (2022, Nature Genetics)
  • "Genome-wide association analysis of plasma lipidome identifies 495 genetic associations" (2023, Nature Communications)
  • "A first update on mapping the human genetic architecture of COVID-19" (2022, Nature)
  • "The role of polygenic risk and susceptibility genes in breast cancer over the course of life" (2020, Nature Communications)

Frequent collaborators of Matti Pirinen include:

  • Samuli Ripatti (38 joint publications)
  • Aarno Palotie (30 joint publications)
  • Mark J. Daly (24 joint publications)
  • Nina Mars (19 joint publications)
  • Taru Tukiainen (19 joint publications)

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

    Andrew I R Maas;David K Menon;P David Adelson;Nada Andelic

  • Transcriptome and genome sequencing uncovers functional variation in humans

    Tuuli Lappalainen;Michael Sammeth;Marc R. Friedländer;Peter A. C. ‘t Hoen

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D M Evans;Spencer Cca.;J J Pointon;Z Su

  • Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

    Johannes Kettunen;Ayşe Demirkan;Ayşe Demirkan;Peter Würtz;Harmen H M Draisma

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • FINEMAP: efficient variable selection using summary data from genome-wide association studies

    Christian Benner;Chris C.A. Spencer;Aki S. Havulinna;Veikko Salomaa

  • The fine-scale genetic structure of the British population

    Stephen Leslie;Stephen Leslie;Bruce Winney;Garrett Hellenthal;Dan Davison

  • Bayesian refinement of association signals for 14 loci in 3 common diseases.

    Julian B. Maller;Gilean McVean;Gilean McVean;Jake Byrnes;Damjan Vukcevic

  • Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study

    Ewout W. Steyerberg;Ewout W. Steyerberg;Eveline Wiegers;Charlie Sewalt;Andras Buki

  • Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

    C Bellenguez;S Bevan;A Gschwendtner;Spencer Cca.

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D.M. Evans;C.C.A. Spencer;J.J. Pointon;Z. Su

  • A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease

    V. Plagnol;M.A. Nalls;J.M. Bras;D.G. Hernandez;D.G. Hernandez

  • The impact of low-frequency and rare variants on lipid levels.

    Ida Surakka;Ida Surakka;Momoko Horikoshi;Reedik Mägi;Antti-Pekka Sarin;Antti-Pekka Sarin

  • A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1

    A. Strange;F. Capon;C. C. A. Spencer;J. Knight

  • Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

    C. Bellenguez;S. Bevan;A. Gschwendtner;C. C. A. Spencer

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    L. C. Tsoi;S. L. Spain;J. Knight;E. Ellinghaus

Frequent Co-Authors

Samuli Ripatti
Samuli Ripatti University of Helsinki
Aarno Palotie
Aarno Palotie University of Helsinki
Aki S. Havulinna
Aki S. Havulinna Finnish Institute for Health and Welfare
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Peter Donnelly
Peter Donnelly University of Oxford
Veikko Salomaa
Veikko Salomaa Finnish Institute for Health and Welfare
Jenefer M. Blackwell
Jenefer M. Blackwell Telethon Kids Institute
Elvira Bramon
Elvira Bramon University College London
Janusz Jankowski
Janusz Jankowski University College of Osteopathy

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