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Chris C. A. Spencer

Chris C. A. Spencer

D-Index & Metrics

Genetics

D-Index
75
Citations
65077
World Ranking
1855
National Ranking
230

Overview

Chris C. A. Spencer is affiliated with Genomics plc in the United Kingdom. Their research focus spans multiple areas within medicine and the biological sciences. The main fields of study covered in their publications include Medicine and Biochemistry, Genetics and Molecular Biology.

The subfields of study where their work is concentrated are Genetics, Surgery, Epidemiology, Molecular Biology, and Pulmonary and Respiratory Medicine. The scientist's research topics encompass Genetic Associations and Epidemiology, Lipoproteins and Cardiovascular Health, Winter Sports Injuries and Performance, Agriculture and Farm Safety, Injury Epidemiology and Prevention, Radiomics and Machine Learning in Medical Imaging, and AI in cancer detection.

Recent notable papers include:

  • "Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review," 2023, published in Annals of Oncology
  • "Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction," 2021, published in Circulation Genomic and Precision Medicine
  • "Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure," 2021, published in Nature Communications
  • "An integrated polygenic and clinical risk tool enhances coronary artery disease prediction," 2020, published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Bayesian model comparison for rare-variant association studies," 2021, published in The American Journal of Human Genetics

Frequent coauthors collaborating with Chris C. A. Spencer include Fernando Riveros-Mckay, Michael E. Weale, Rachel Moore, Saskia Selzam, and Eva Krapohl.

The scientist's publications have appeared in various venues, most commonly Poster presentations, Zenodo (CERN European Organization for Nuclear Research), Abstracts with programs - Geological Society of America, Free Radical Biology and Medicine, and Annals of Oncology.

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • A haplotype map of the human genome

    John W. Belmont;Andrew Boudreau;Suzanne M. Leal;Paul Hardenbol

  • A second generation human haplotype map of over 3.1 million SNPs

    Kelly A. Frazer;Dennis G. Ballinger;David R. Cox;David A. Hinds

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genome-wide detection and characterization of positive selection in human populations

    Pardis C. Sabeti;Pardis C. Sabeti;Patrick Varilly;Patrick Varilly;Ben Fry;Jason Lohmueller

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Identification of loci associated with schizophrenia by genome-wide association and follow-up

    Michael C. O'Donovan;Nicholas Craddock;Nadine Norton;Hywel Williams

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

    Chris C. A. Spencer;Zhan Su;Peter Donnelly;Jonathan Marchini

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • FINEMAP: efficient variable selection using summary data from genome-wide association studies

    Christian Benner;Chris C.A. Spencer;Aki S. Havulinna;Veikko Salomaa

Frequent Co-Authors

Peter Donnelly
Peter Donnelly University of Oxford
Aiden Corvin
Aiden Corvin Trinity College Dublin
Elvira Bramon
Elvira Bramon University College London
Sarah Hunt
Sarah Hunt European Bioinformatics Institute
Matti Pirinen
Matti Pirinen University of Helsinki
Matthew A. Brown
Matthew A. Brown Guy's and St Thomas' NHS Foundation Trust
Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Stephen Sawcer
Stephen Sawcer University of Cambridge
Aarno Palotie
Aarno Palotie University of Helsinki
Jenefer M. Blackwell
Jenefer M. Blackwell Telethon Kids Institute

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