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Molecular Biology

D-Index
67
Citations
24731
World Ranking
1547
National Ranking
120

Research.com Recognitions

  • 2018 - Fellow of the Royal Society of Edinburgh
  • 2014 - Member of Academia Europaea
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Elaine Dzierzak is affiliated with the University of Edinburgh in the United Kingdom. Their research is primarily situated within the domains of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology, reflecting a multidisciplinary approach to biomedical science.

Their work spans specific subfields including Immunology, Cell Biology, Molecular Biology, Hematology, and Epidemiology. The scientist's main topics of research cover Zebrafish Biomedical Research Applications, Immune Cells in Cancer, Single-cell and Spatial Transcriptomics, Acute Myeloid Leukemia Research, T-cell and B-cell Immunology, Hematopoietic Stem Cell Transplantation, and Pluripotent Stem Cells Research.

Elaine Dzierzak has contributed to a number of recent papers, with notable publications including:

  • "Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells" (2020, Cell Reports)
  • "Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation" (2020, The EMBO Journal)
  • "E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates" (2021, Science Immunology)
  • "Bioengineering Self-Organizing Signaling Centers to Control Embryoid Body Pattern Elaboration" (2021, ACS Synthetic Biology)
  • "Embryonic Origins of the Hematopoietic System: Hierarchies and Heterogeneity" (2022, HemaSphere)

Frequent co-authors collaborating with Elaine Dzierzak include:

  • Chris S. Vink
  • Samanta A. Mariani
  • Antonio Maglitto
  • Anna Popravko
  • Emma de Pater

Their publications mainly appear in venues such as:

  • Experimental Hematology
  • HemaSphere
  • Blood Advances
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The EMBO Journal

Elaine Dzierzak's academic recognition includes several distinctions:

  • Fellow of the Royal Society of Edinburgh (2018)
  • Member of Academia Europaea (2014)
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Definitive Hematopoiesis Is Autonomously Initiated by the AGM Region

    Alexander Medvinsky;Elaine Dzierzak

  • Development of hematopoietic stem cell activity in the mouse embryo

    Albrecht Müller;A. Medvinsky;John Strouboulis;Frank Grosveld

  • Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

    Michael J. Chen;Tomomasa Yokomizo;Brandon M. Zeigler;Elaine Dzierzak

  • In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

    Jean-Charles Boisset;Wiggert van Cappellen;Charlotte Andrieu-Soler;Niels Galjart

  • Of lineage and legacy: the development of mammalian hematopoietic stem cells

    Elaine Dzierzak;Nancy A Speck

  • Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo

    Marella F.T.R. de Bruijn;Nancy A. Speck;Marian C.E. Peeters;Elaine Dzierzak

  • Combinatorial transcriptional control in blood stem/progenitor cells: Genome-wide analysis of ten major transcriptional regulators

    Nicola K. Wilson;Samuel D. Foster;Xiaonan Wang;Kathy Knezevic

  • Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis.

    Pier Paolo Pandolfi;Pier Paolo Pandolfi;Matthew E. Roth;Alar Karis;Alar Karis;Mark W. Leonard

  • An early pre-liver intraembryonic source of CFU-S in the developing mouse

    Alexander L. Medvinsky;Nina L. Samoylina;Albrecht M. Müller;Elaine A. Dzierzak

  • Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo

    Trista E North;Marella F.T.R de Bruijn;Terryl Stacy;Laleh Talebian

  • The Murine Placenta Contains Hematopoietic Stem Cells within the Vascular Labyrinth Region

    Katrin Ottersbach;Elaine Dzierzak

  • Hematopoietic Stem Cells Localize to the Endothelial Cell Layer in the Midgestation Mouse Aorta

    Marella F.T.R de Bruijn;Xiaoqian Ma;Catherine Robin;Katrin Ottersbach

  • Hematopoietic Stem Cell Development Is Dependent on Blood Flow

    Trista E. North;Wolfram Goessling;Marian Peeters;Pulin Li

  • Lineage-specific expression of a human β -globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells

    Elaine A. Dzierzak;Thalia Papayannopoulou;Richard C. Mulligan

  • Characterization of the First Definitive Hematopoietic Stem Cells in the AGM and Liver of the Mouse Embryo

    María José Sánchez;Alan Holmes;Colin Miles;Elaine Dzierzak

  • Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

    Serge A. van de Pavert;Manuela Ferreira;Rita G. Domingues;Hélder Ribeiro

  • Erythropoiesis: Development and Differentiation

    Elaine Dzierzak;Sjaak Philipsen

  • GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.

    Kam-Wing Ling;Katrin Ottersbach;Jan Piet van Hamburg;Aneta Oziemlak

  • Efficient Hematopoietic Differentiation of Human Embryonic Stem Cells on Stromal Cells Derived from Hematopoietic Niches

    Maria H. Ledran;Anna Krassowska;Lyle Armstrong;Ian Dimmick

  • Mouse embryonic hematopoiesis

    Elaine Dzierzak;Alexander Medvinsky

Frequent Co-Authors

Nancy A. Speck
Nancy A. Speck University of Pennsylvania
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Trista E. North
Trista E. North Boston Children's Hospital
María José Sánchez
María José Sánchez University of Granada
Berthold Göttgens
Berthold Göttgens University of Cambridge
Pierre Charbord
Pierre Charbord Université Paris Cité
Leonard I. Zon
Leonard I. Zon Harvard University
Pier Paolo Pandolfi
Pier Paolo Pandolfi Beth Israel Deaconess Medical Center
Dies Meijer
Dies Meijer University of Edinburgh

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