His primary scientific interests are in Genetics, Gene, Molecular biology, Chromatin and Transcription. His Genetics research is multidisciplinary, relying on both Fetal hemoglobin and Computational biology. His Molecular biology research incorporates themes from Tsix, Gene expression profiling, Enhancer, E-box and KLF1.
His Chromatin study integrates concerns from other disciplines, such as Protein subunit, CTCF and Mitosis. The Transcription study combines topics in areas such as DNA damage, RNA interference, DNA repair, Cell biology and RNA polymerase II. His study in Cell biology is interdisciplinary in nature, drawing from both Cell culture, microRNA and Cellular differentiation.
Wilfred F. J. van IJcken mostly deals with Genetics, Cell biology, Gene, Chromatin and Molecular biology. As part of the same scientific family, Wilfred F. J. van IJcken usually focuses on Genetics, concentrating on Computational biology and intersecting with Genomic organization. His Cell biology study deals with Transcription intersecting with RNA polymerase II.
His studies in Chromatin integrate themes in fields like Enhancer, Promoter and Histone. His Gene expression profiling research integrates issues from Microarray, Internal medicine and Immunology. Wilfred F. J. van IJcken has included themes like Cancer research and Oncology in his Internal medicine study.
His scientific interests lie mostly in Cell biology, Gene, Genetics, Chromatin and Transcription factor. Wilfred F. J. van IJcken has researched Cell biology in several fields, including RNA, Apoptosis and Germline. His Gene study combines topics in areas such as T cell and Molecular biology.
The various areas that he examines in his Molecular biology study include HBG1, Fetal hemoglobin, HBG2, Hereditary persistence of fetal hemoglobin and Gene expression profiling. Wilfred F. J. van IJcken combines subjects such as Enhancer, Regulation of gene expression, Gene duplication and Cornelia de Lange Syndrome with his study of Chromatin. His research integrates issues of Embryonic stem cell, Cellular differentiation, Immunoprecipitation, Erythropoiesis and Chromatin immunoprecipitation in his study of Transcription factor.
Wilfred F. J. van IJcken spends much of his time researching Chromatin, Cell biology, Regulation of gene expression, Gene and Enhancer. His biological study spans a wide range of topics, including Centromere, Wnt signaling pathway and Embryonic stem cell. His studies deal with areas such as Histone deacetylase, Immunoglobulin E and Mast cell as well as Cell biology.
The study incorporates disciplines such as Establishment of sister chromatid cohesion, Cohesin, Cohesin complex, Protein subunit and Transcriptional regulation in addition to Regulation of gene expression. His Gene research is under the purview of Genetics. The concepts of his Enhancer study are interwoven with issues in Gene dosage, Promoter and Computational biology.
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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Marjolein P. Baar;Renata M.C. Brandt;Diana A. Putavet;Julian D.D. Klein.
Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells.
Jessica Zuin;Jesse R. Dixon;Michael I. J. A. van der Reijden;Zhen Ye;Zhen Ye.
Proceedings of the National Academy of Sciences of the United States of America (2014)
Gene expression-based classification of non-small cell lung carcinomas and survival prediction.
Jun Hou;Joachim Aerts;Bianca den Hamer;Wilfred van IJcken.
PLOS ONE (2010)
Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin
Joseph Borg;Joseph Borg;Petros Papadopoulos;Marianthi Georgitsi;Laura Gutiérrez.
Nature Genetics (2010)
The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
Erik Splinter;Elzo de Wit;Elphège P. Nora;Petra Klous.
Genes & Development (2011)
Exacerbated innate host response to SARS-CoV in aged non-human primates
Saskia L. Smits;Anna de Lang;Judith M A van den Brand;Lonneke M Leijten.
PLOS Pathogens (2010)
Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene
Manfred Kayser;Fan Liu;A. Cecile J.W. Janssens;Fernando Rivadeneira.
American Journal of Human Genetics (2008)
The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation
Eric Soler;Charlotte Andrieu-Soler;Ernie de Boer;Jan Christian Bryne.
Genes & Development (2010)
Ovarian cancer cell line panel (OCCP): Clinical importance of in vitro morphological subtypes
Corine M. Beaufort;Jean C. A. Helmijr;Anna M. Piskorz;Marlous Hoogstraat.
PLOS ONE (2014)
MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16
Hang Yin;Alessandra Pasut;Vahab D. Soleimani;C. Florian Bentzinger.
Cell Metabolism (2013)
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