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Molecular Biology
Canada
2026

D-Index & Metrics

Molecular Biology

D-Index
120
Citations
66421
World Ranking
256
National Ranking
6

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Canada Leader Award
  • 2025 - Research.com Molecular Biology in Canada Leader Award
  • 2023 - Research.com Molecular Biology in Canada Leader Award
  • 2020 - Fellow of the Royal Society, United Kingdom
  • 2006 - Fellow of the Royal Society of Canada Academy of Science

Overview

Michael A. Rudnicki is affiliated with the Ottawa Hospital Research Institute in Canada and specializes in the field of Biochemistry, Genetics, and Molecular Biology. Their research primarily focuses on molecular biology, genetics, surgery, aging, and biomedical engineering, with an emphasis on muscle physiology and related disorders.

Themes prominent in their work include muscle physiology and disorders, extracellular vesicles in disease, tissue engineering and regenerative medicine, genetics, aging and longevity in model organisms, RNA interference and gene delivery, pluripotent stem cells research, as well as genetic and kidney cyst diseases.

Recent publications authored or co-authored by Rudnicki include:

  • "Satellite cells in ageing: use it or lose it," 2020, Open Biology
  • "The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells," 2022, Cell stem cell
  • "Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice," 2021, Nature Communications
  • "GLI3 regulates muscle stem cell entry into GAlert and self-renewal," 2022, Nature Communications
  • "Satellite cell contribution to disease pathology in Duchenne muscular dystrophy," 2023, Frontiers in Physiology

Michael A. Rudnicki has collaborated frequently with several co-authors, including David Datzkiw, Peter Feige, Alexander Y. Lin, Uxía Gurriarán-Rodríguez, and Marie E. Esper. Each of these collaborators has appeared six times alongside Rudnicki in published research.

Key venues for their publications include Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Skeletal Muscle, and Methods in Molecular Biology. Their output spans over 70 published works in biochemistry, genetics, and molecular biology, with 52 focusing on molecular biology specifically.

Michael A. Rudnicki has been recognized by prestigious scientific communities, being named a Fellow of the Royal Society in the United Kingdom in 2020, and a Fellow of the Royal Society of Canada in 2006, with the latter citing the Academy of Science.

Best Publications

  • Cellular and Molecular Regulation of Muscle Regeneration

    Sophie B. P. Chargé;Michael A. Rudnicki

  • PRDM16 controls a brown fat/skeletal muscle switch

    Patrick Seale;Bryan Bjork;Wenli Yang;Shingo Kajimura

  • Pax7 is required for the specification of myogenic satellite cells.

    Patrick Seale;Luc A Sabourin;Adele Girgis-Gabardo;Ahmed Mansouri

  • MyoD or Myf-5 is required for the formation of skeletal muscle

    Michael A. Rudnicki;Patrick N.J. Schnegelsberg;Ronald H. Stead;Thomas Braun

  • Satellite Cells and the Muscle Stem Cell Niche

    Hang Yin;Feodor Price;Michael A. Rudnicki

  • Simplified mammalian DNA isolation procedure.

    Peter W. Laird;Alice Zijderveld;Koert Linders;Michael A. Rudnicki

  • Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

    Aaron W. B. Joe;Lin Yi;Anuradha Natarajan;Fabien Le Grand

  • Asymmetric Self-Renewal and Commitment of Satellite Stem Cells in Muscle

    Shihuan Kuang;Kazuki Kuroda;Fabien Le Grand;Michael A. Rudnicki

  • Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

    Peter Mombaerts;Alan R. Clarke;Michael A. Rudnicki;John Iacomini

  • Building Muscle: Molecular Regulation of Myogenesis

    C. Florian Bentzinger;Yu Xin Wang;Michael A. Rudnicki

  • Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development.

    Michael A. Rudnicki;Thomas Braun;Shuji Hinuma;Rudolf Jaenisch

  • Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation

    Atsushi Asakura;Motohiro Komaki;Michael A. Rudnicki

  • A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal

    Robin J. Parks;Liane Chen;Martina Anton;Uma Sankar

  • The molecular regulation of myogenesis.

    Luc A Sabourin;Michael A Rudnicki

  • Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death.

    Thomas Braun;Michael A. Rudnicki;Hans-Henning Arnold;Rudolf Jaenisch

  • MyoD is required for myogenic stem cell function in adult skeletal muscle.

    L A Megeney;B Kablar;K Garrett;J E Anderson

  • Myogenic specification of side population cells in skeletal muscle.

    Atsushi Asakura;Patrick Seale;Adele Girgis-Gabardo;Michael A. Rudnicki

  • A new look at the origin, function, and "stem-cell" status of muscle satellite cells.

    Patrick Seale;Michael A. Rudnicki

  • Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

    Zhoutao Chen;Andrew C. Karaplis;Susan L. Ackerman;Igor P. Pogribny

  • Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration.

    Anna Polesskaya;Patrick Seale;Michael A Rudnicki

Frequent Co-Authors

Hang Yin
Hang Yin Tsinghua University
Shihuan Kuang
Shihuan Kuang Purdue University West Lafayette
Miguel A. Andrade-Navarro
Miguel A. Andrade-Navarro Johannes Gutenberg University of Mainz
Michael W. McBurney
Michael W. McBurney University of Ottawa
Frank L. Graham
Frank L. Graham McMaster University
F. Jeffrey Dilworth
F. Jeffrey Dilworth University of Wisconsin–Madison
Bernd Mayer
Bernd Mayer University of Graz
Thomas Braun
Thomas Braun Max Planck Society
Zoltán Prohászka
Zoltán Prohászka Semmelweis University

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